[{"newsid":246,"title":"Turkey vacation in Corona times: The country is no longer a high incidence area","newsContent":"

Turkey is one of the most popular travel destinations for Germans. The country on the Bosporus is still considered a corona risk area, but is no longer classified as a high-incidence area from June 6th. These special features are to be expected when traveling to Istanbul, Bodrum, Antalya or Side.

\r\n\r\n

Turkey no longer a high incidence area from June 6th
Facilitation of the entry of vaccinated and convalescent people
Negative corona test when entering and leaving the country is compulsory
Current incidence: 59.0 infected per 100,000 population in the last seven days

\r\n\r\n

The current situation in Turkey

\r\n\r\n

Turkey is one of the countries in Europe most affected by the corona pandemic. Most recently, the reported numbers have fallen again. Currently, the incidence value of 59.0 infected people per 100,000 population in the last seven days (as of June 4, source: Johns Hopkins University) is just above the critical mark of 50 and also higher than currently in Germany.

\r\n\r\n

The Robert Koch Institute (RKI) lists all of Turkey as a corona risk area. The Foreign Office warns against unnecessary tourist trips to Turkey.

\r\n\r\n

Important for entering Turkey

\r\n\r\n

Foreign Office travel warning: YES
Corona risk area: YES
Corona test upon entry: YES (PCR test max. 72 hours old, antigen rapid test max. 48 hours old)
Entry form required: YES (Download *)
Quarantine after entry: NO

\r\n\r\n

\r\nEntry form and corona test

\r\n\r\n

$\"antalya$

\r\n\r\n

You have to register online 72 hours before entering Turkey. The form is available on the website of the Turkish Ministry of Health *, also in German. After registration, travelers receive an authorization code ("HES code") which must be shown during controls in the country. The code can also be obtained in Turkey via SMS or a smartphone app.

\r\n\r\n

Upon entry, you have to present a negative Covid-19-PCR test, which must not be older than 72 hours at the time of entry. Alternatively, a rapid antigen test that is not more than 48 hours old can be shown. The compulsory test does not apply to children under six years of age.

\r\n\r\n

Vaccinated and convalescents are exempt from the test requirement. You need official proof of a complete vaccination from at least 14 days ago, or medical documentation of recovery from a corona infection no more than six months ago.

\r\n\r\n

When traveling by air, the test must be presented at check-in at the departure airport in Turkey.

\r\n\r\n

On arrival, temperature measurements are carried out at the airport and additional health examinations are arranged in the event of increased body temperature or other corona symptoms.

\r\n","createDate":"2021-06-05T15:54:00","status":1,"picture":"https://cdn.clinicways.com//news/603c832d-37d8-4e9e-88d1-681d2b748201/Main.JPEG","guid":"603c832d-37d8-4e9e-88d1-681d2b748201","newsType":1,"seoUrl":"turkey-vacation-in-corona-times-the-country-is-no-longer-a-high-incidence-area","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Turkey is one of the most popular travel destinations for Germans. The country on the Bosporus is still considered a corona risk area, but is no longer classified as a high incidence area from June 6th.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.adac.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":243,"title":"R-value increases, but less active cases: The current figures on the corona situation","newsContent":"

How many new infections does the RKI report today? How many cases are still active, how many people recovered or died? How many others does an infected person infect on average? FOCUS Online provides you with the most important data on the development of the pandemic in Germany on Monday.

\r\n\r\n

Monday, December 7th: The Covid-19 situation in the morning

\r\n\r\n

\r\n1. New infections

\r\n\r\n

\r\nThe Robert Koch Institute (RKI) reported 12,332 new infections with Sars-CoV-2 on Monday morning. According to the RKI, a total of 1,183,655 people in Germany have been infected with the new corona virus since the pandemic began.

\r\n\r\n

2. Dead, recovered, active cases

\r\n\r\n

\r\nThe RKI reported 147 new deaths related to Covid-19 on Monday morning. A total of 18,919 people in Germany have died in connection with the disease caused by the new coronavirus.

\r\n\r\n

According to the RKI, around 863,300 people have recovered. This means that 301,500 cases are currently active. That is almost 4,700 less than the day before (306,200).

\r\n\r\n

3. 7 day incidence

\r\n\r\n

\r\nAccording to the RKI dashboard, the 7-day incidence on Monday morning is again highest in the state of Saxony at 321.9. Compared to the previous day (301) it has risen again. The second most affected is Berlin (184.2), where the incidence has recently fallen slightly (previous day: 182). In Bavaria the incidence has increased slightly compared to Sunday (175) and is now 176.3.

\r\n\r\n

According to the RKI situation report on Sunday, 15 districts exceeded an incidence of more than 345 cases per 100,000 inhabitants, five of them even exceeded 400. The district of Regen has an incidence value of 581.3, the district of Saxon Switzerland-Eastern Ore Mountains 534.6. In the Bautzen district the incidence is 470, in Hildburghausen 452.6 and in the urban district of Passau 439.4.

\r\n\r\n

This is followed by the districts of Zwickau (395.2), Meißen (393) and Görlitz (385.4). Then also the districts of Altenburger Land (379.2), Erzgebirgskreis (375), Freyung-Grafenau (371.4), the city district of Ludwigshafen (366.9), the Saale-Orla district (366.1) and the city of Nuremberg (350.7) and the district of central Saxony (345.3).

\r\n\r\n

4. R value

\r\n\r\n

\r\nThe R value indicates how many people an infected person usually infects. According to the RKI situation report from Sunday, it is 1.21 in Germany and has thus increased slightly compared to the previous day (1.13). This means that 100 infected people now infect an average of 121 more people. From a value of 0.7 or lower, it is assumed that the infection process becomes more controllable.

\r\n\r\n

The 7-day R, which is less volatile, was 1.10 on Sunday evening. It has not changed compared to the previous day.

\r\n\r\n

5. Intensive care bed occupancy in Germany

\r\n\r\n

\r\nThe Divi intensive care register reported 4,117 Covid-19 patients in intensive care beds on Monday morning. That's 9 more than on Sunday (4,108). Of the 4,117 patients, 2,466 are connected to ventilators, up from 2,457 the day before.

\r\n\r\n

According to the intensive care register, a total of 21,642 of 27,175 operable intensive care beds are currently occupied - this corresponds to around 80 percent. In addition, 11,768 beds are available as an emergency reserve, which could be set up within seven days.

\r\n","createDate":"2021-01-13T01:14:00","status":1,"picture":"https://cdn.clinicways.com/news/503055df-9a72-4694-aedb-7d2fb28526f8/Main.JPEG","guid":"503055df-9a72-4694-aedb-7d2fb28526f8","newsType":1,"seoUrl":"r-value-increases-but-less-active-cases-the-current-figures-on-the-corona-situ","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"How many new infections does the RKI report today? How many cases are still active, how many people recovered or died? How many others does an infected person infect on average? FOCUS Online provides you with the most important data on the development of the pandemic in Germany on Monday.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.focus.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":240,"title":"Terrifying balance: the past three days there were more corona deaths than cancer","newsContent":"

All the important numbers, data and facts about the Covid 19 pandemic: In the months of the virus crisis, the corona pandemic has also developed into a real jungle of information. FOCUS Online wants to give you orientation - and shows you the most important, current trends on Covid-19 every day.

\r\n\r\n

December 21, 2020: Sweden and Japan took the Corona special route - and are now paying the price for it
\r\nMore than 1.5 million people in Germany have been proven to be infected with Sars-CoV-2. The RKI reported 16,643 new cases on Monday morning alone - about 300 more than on the Monday of the previous week. In order to get the numbers under control, the Federal Republic of Germany has recently tightened its corona measures: A “lockdown light”, which was in effect from November 2nd to December 15th, was followed by the second hard lockdown after spring on December 16th .

\r\n\r\n

Germany is thus following a similar path in the crisis as most western countries. But there are also nations that don't believe in a lockdown: In April, the Swedish state epidemiologist Anders Tegnell even called the lockdowns in neighboring countries “ridiculous”. Sweden relied on "recommendations" instead of rules and thus took a Europe-wide unique, but also controversial path in the fight against the virus.

\r\n\r\n

Japan relied on citizens' sense of responsibility

\r\n\r\n

\r\nJapan has taken a similar path: instead of a lockdown, the country has relied solely on the sense of responsibility of its citizens since the beginning of the pandemic. In general, however, in Japan it was already the case before the pandemic that people often wear face masks in public - so nobody had to get used to it again. The strategy of relying only on masks and strict contact tracking seemed to work, at least in the first wave.

\r\n\r\n

New infections reported daily skyrocketed

\r\n\r\n

\r\nJapan got through the first Corona wave comparatively lightly and was even considered a "model country". At its peak in mid-April, there were 545 new infections with Sars-CoV-2 every day on a 7-day average. Then the numbers ebbed and the first wave was over in early May.

\r\n\r\n

In July, however, the infection curve rose again, this time significantly steeper. The second wave peaked in mid-August with around 1,360 new infections a day on a 7-day average. This infection process also seemed to be under control until the beginning of September.

\r\n\r\n

In order to stimulate the economic situation in the country, Japan started a subsidy campaign for domestic tourism during the second wave in July. With “Go To Travel”, up to 50 percent of tourism expenditures such as accommodation and transport costs are subsidized by the state. Critics see the funding campaign as one reason for the recent significant increase in the number of infections.

\r\n\r\n

Experts warn of overloading the health system

\r\n\r\n

\r\nExperts are now talking of a third wave of infections that threatens to overload Japan's health system: the infection curve has skyrocketed again since the beginning of November, and on December 20 it will not only reach a new high of around 2,660 new infections every day, but also the number of infections seems to continue unbroken. In total, almost 200,000 people have been infected with Sars-CoV-2 since the epidemic began in Japan.

\r\n","createDate":"2021-01-13T01:11:00","status":1,"picture":"https://cdn.clinicways.com/news/0f7a07c3-84e4-4138-8c5e-2786a9e86667/Main.JPEG","guid":"0f7a07c3-84e4-4138-8c5e-2786a9e86667","newsType":1,"seoUrl":"terrifying-balance-the-past-three-days-there-were-more-corona-deaths-than-cance","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"All the important numbers, data and facts about the Covid 19 pandemic: In the months of the virus crisis, the corona pandemic has also developed into a real jungle of information. FOCUS Online wants to give you orientation - and shows you the most important, current trends on Covid-19 every day.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.focus.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":237,"title":"Day 1 to 5 are required: When corona infected people are most infectious","newsContent":"

A Scottish research team has evaluated 79 studies on Sars-CoV-2 to find out when infected people are most contagious. On the basis of their results, they suggest a shorter isolation period - so that more people stick to the rules.

\r\n\r\n

Stricter corona measures have been in place in Germany since December 1 - this also includes stricter contact restrictions to break chains of infection. Anyone who tested positive for Sars-CoV-2 must isolate themselves at home until the responsible health department cancels the measure. People who have had contact with the infected person from the second day before the onset of symptoms up to at least 10 days after the onset of symptoms must go into quarantine.

\r\n\r\n

But when exactly does the sick person pose the greatest risk of infection? This is what a research team around the infectious agent and virologist Muge Cevik from the University of St. Andrew wanted to find out. Their results suggest that infected people may have to stay at home less than before - and the spread of the virus could still be prevented.

\r\n\r\n

Previously: Infectious up to ten days after the onset of symptoms

\r\n\r\n

\r\nAccording to the Robert Koch Institute (RKI), the exact period in which the contagiousness exists has not yet been clearly defined; the information on this varied. It was considered certain, however, that the contagion is greatest around the onset of symptoms and that a significant proportion of the transmission occurs before the first clinical symptoms appear.

\r\n\r\n

“In addition, it is certain that the contagiousness decreases in the course of the disease and that seriously ill patients sometimes excrete the infectious virus longer than patients with mild to moderate disease,” reports the RKI.

\r\n\r\n

According to the current state of knowledge, in the case of mild to moderate illness, the contagion significantly decreases ten days after the onset of symptoms; In the case of severe illnesses, however, patients could be contagious for considerably longer than ten days after the onset of symptoms.

\r\n\r\n

Researchers report a shorter risk of infection
\r\nIn their systematic review and meta-analysis, the Scottish research team around Cevik have now come to different results, which they have published in the renowned specialist journal “The Lancet”.

\r\n\r\n

Covid 19 patients had the highest viral load in the upper respiratory tract up to two days before their symptoms broke out and up to five days afterwards - then the risk of infection is greatest. Cevik emphasizes that it does not depend on the severity of the symptoms. “Anyone who notices signs of illness, no matter how mild, should isolate themselves immediately. Because by the time we get the test result, they could be past their most infectious phase. ”The earlier those affected isolated themselves, the better.

\r\n\r\n

Asymptomatic infected people also seem to have about the same amount of virus in them as patients with symptoms. With them, however, the virus apparently disappears from the body more quickly, explains the researcher.

\r\n\r\n

From day 9 no living virus was detected

\r\n\r\n

\r\nIn addition to the studies on Sars-CoV-2, the scientists also evaluated eight studies on Sars-CoV-1 and eleven on Mers-CoV. Compared to Sars-CoV-2, the first Sars virus and Mers-CoV only multiply slowly in the upper airways - with Sars-CoV-1, virus excretion via the upper airways is highest after 12 to 14 days of infection, at Mers-CoV patients after 7 to 10 days. There is practically no transmission by asymptomatic or presymptomatic persons.

\r\n\r\n

Cevik's team also came to the result that with a Sars-CoV-2 infection from day 9 onwards, there were no longer enough viable viruses detectable in the upper respiratory tract that could cause an infection: “In none of the studies was it higher despite persistently Viral load of a live virus detected after the 9th day of illness ”. However, the virus genes were still present for a long time in the upper and lower airways, in the blood and in the stool. But even here there is no risk of infection, stated Cevik.

\r\n\r\n

However, this statement should be interpreted with caution, warned the "Ärzteblatt". Because the smears showed only individual virus genes with the polymerase chain reaction - they would not have to come from viruses capable of replication. It could therefore also be the remains of an infection that has already been overcome. Infectiousness cannot be completely ruled out.

\r\n\r\n

Study director suggests shorter isolation periods

\r\n\r\n

According to the evaluated studies, the mean duration of a positive smear was 17.0 days in the upper airways, 14.6 days in the lower airways, 17.2 days in the stool samples and 16.6 days in the serum samples. The longest proven elimination times were 83 days in the upper airways, 59 days in the lower airways, 126 days in the stool and 60 days in the serum.

\r\n\r\n

Based on their results, Cevik suggested reducing the isolation period to five days. This could, so her hope, bring more infected people to actually stick to the isolation, she told the "New York Times". Their reasoning is likely to be based on a survey from August that only 20 percent of respondents in Great Britain actually follow the rules of self-isolation.

\r\n\r\n

Because of the "currently limited test capacities and the frequency of colds in the winter months", which makes it impossible to confirm all Covid-19 diseases in Germany through tests, the RKI also advises "if you have any respiratory symptoms for at least 5 Days to isolate at home and only end the isolation after another 48 hours without symptoms. "

\r\n","createDate":"2021-01-13T01:09:00","status":1,"picture":"https://cdn.clinicways.com/news/80456691-121f-4e0b-9cf5-3fef91de6679/Main.JPEG","guid":"80456691-121f-4e0b-9cf5-3fef91de6679","newsType":1,"seoUrl":"day-1-to-5-are-required-when-corona-infected-people-are-most-infectious","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"A Scottish research team has evaluated 79 studies on Sars-CoV-2 to find out when infected people are most contagious. On the basis of their results, they suggest a shorter isolation period - so that more people stick to the rules.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.focus.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":234,"title":"What a life without taste and smell means","newsContent":"

The importance of our sense of smell and taste is often only recognized when the senses no longer perform their tasks. There are many reasons for a disorder. In most cases, however, it is only temporary and treatable, ”explains Georg Langmayr, specialist group representative for ear, nose and throat diseases at the Medical Association for Upper Austria. “Our nose can perceive several thousand scents. The tongue, on the other hand, only distinguishes five flavors - salty, sweet, sour, bitter and umami. In order to perceive aromas, an air flow to the olfactory cells of the nose, of which humans have around 30 million, is required. "

\r\n\r\n

Social and health problems are inevitable

\r\n\r\n

\r\nIn many cases, sufferers do not notice a disturbance of the sense of smell immediately, as well as the effects on the sense of taste. The result: Malnutrition and malnutrition can occur, for example, as appetite decreases or food is over-seasoned. If you lose your sense of smell, there is also the risk of consuming spoiled food, which in the worst case can lead to food poisoning. It is also dangerous if the smell of burning is no longer perceptible.

\r\n\r\n

“Not being able to smell or taste anything anymore affects the lives of those affected. They often reduce their social life as many activities involve eating. In addition, there is a fear of body odor, which is why perfumes and deodorants are sometimes overdosed. At the same time, the disturbance means that important, unconsciously perceived information is missing in non-verbal communication, ”Georg Langmayr points out to the consequences.

\r\n\r\n

When the food suddenly tastes boring

\r\n\r\n

\r\nA multitude of diseases can lead to an odor or taste disorder or even loss. In autumn and winter, colds and the flu are primarily responsible for the fact that the inhaled air is obstructed on its way to the olfactory mucosa. Disturbances are also possible as a result of skull injuries, for example from a fall or blow to the head. In addition, nasal polyps and other diseases of the paranasal sinuses, a changed hormone balance (e.g. due to pregnancy), a stroke or side effects of medication can impair the sense of smell and taste, as can smoking and alcohol consumption. What is less well known is that olfactory performance diminishes with age, as the ability of the olfactory cells to renew themselves is lost.

\r\n\r\n

Another cause has been keeping the world in suspense since March: the corona virus. Even if research is still in its infancy, studies show that around two thirds of those infected with COVID19 lose their sense of smell and taste. Above all, the perception of bitter or sweet flavors seems to be disturbed. With a view to the coming cold and flu season, this is an important finding for differential diagnostics. There is a good chance that the disorder will reappear, although the sense of taste seems to regenerate faster than the sense of smell, in which the renewal of the sensory cells takes several months.

\r\n\r\n

Early diagnosis is important

\r\n\r\n

\r\n"If smelling and tasting are only limited or not possible at all, an ENT specialist should definitely be consulted for further clarification," recommends Georg Langmayr. Most of the time, however, the sense of taste and smell come back on their own. If this is not the case, depending on the cause, surgery, such as polyps or a crooked nasal septum, can help. Training with sniffing sticks can also improve sensory perception.

\r\n","createDate":"2021-01-05T00:14:00","status":1,"picture":"https://cdn.clinicways.com/news/254f43eb-d790-4c41-af76-fc045a899618/Main.JPEG","guid":"254f43eb-d790-4c41-af76-fc045a899618","newsType":1,"seoUrl":"what-a-life-without-taste-and-smell-means","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"The importance of our sense of smell and taste is often only recognized when the senses no longer perform their tasks. There are many reasons for a disorder. In most cases, however, it is only temporary and treatable, ”explains Georg Langmayr, specialist group representative for ear, nose and throat diseases at the Medical Association for Upper Austria","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.msn.com/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":231,"title":"Mindshine: SOS exercise against corona fear","newsContent":"

Corona is not only a physical, but also a psychological burden and challenge. How do you deal with all the fears and worries in the long run? How do I not die mentally when the pandemic threatens my existence? Almost all people around the world ask themselves these questions. Mindshine, the first Mental Fitness Coaching App, wants to start right here. It helps to successfully master phases of stress, to be able to put away worries better, to counteract the corona low and to become generally more resilient and more balanced. A gym for the mind with lots of simple exercises.

\r\n\r\n

SOS exercise for excessive worry
\r\nStep 1: write it down. Simply put down on paper what is a burden - the fear itself, but also where it comes from and which areas of life it affects.

\r\n\r\n

Step 2: What feelings does the concern trigger? Write down each feeling (“I feel lonely”) and say it three times. Even verbalizing feelings relieves stress.

\r\n\r\n

Step 3: Breathe away the stress: consciously breathe according to the 4-6-8 pattern for 90 seconds. As you inhale, slowly count to four internally. Hold your breath and count to 6. Count silently to 8 while exhaling. It is scientifically proven that 4-6-8 breathing decreases the heart rate and the perceived stress.

\r\n\r\n

Step 4: “Worst Case Scenario” - describe and write down in detail what the worst consequences would be if the concern were to come true.

\r\n\r\n

Step 5: "Best Case Scenario" - note what could become reality in the best possible case.

\r\n\r\n

Step 6: Formulate a positive belief that deals with the part that you can control yourself. Example: "I am experienced and can offer my employer a lot."

\r\n","createDate":"2021-01-05T00:11:00","status":1,"picture":"https://cdn.clinicways.com/news/a3f9a902-f702-4ab5-96dc-2535715ed81b/Main.JPEG","guid":"a3f9a902-f702-4ab5-96dc-2535715ed81b","newsType":1,"seoUrl":"mindshine-sos-exercise-against-corona-fear","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Corona is not only a physical, but also a psychological burden and challenge. How do you deal with all the fears and worries in the long run? How do I not die mentally when the pandemic threatens my existence? Almost all people around the world ask themselves these questions.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.msn.com/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":228,"title":"Age is not a barrier to successful weight loss, according to a new study","newsContent":"

According to a new study by the University of Warwick's NHS Trust and Coventry and Warwickshire University Hospitals (UHCW) that shows that age is not a barrier, obese patients over the age of 60 can lose as much weight as younger people who just make lifestyle changes apply to lose.
\r\n The researchers hope their results will help correct the prevailing societal misconceptions about the effectiveness of weight loss programs in the elderly and dispel myths about the potential benefits of older people trying to lose weight.
\r\n The results are based on an analysis of patient records from a hospital obesity service and are published in the journal Clinical Endocrinology.
\r\n This retrospective study was conducted at the Warwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism (WISDEM) at the UHCW. The researchers randomly selected 242 patients who participated in the WISDEM-based obesity service between 2005 and 2016, and compared two groups (under 60 and between 60 and 78) on the weight loss they achieved during their time within the year Service.
\r\n In all patients, body weight was measured both before and after lifestyle interventions and coordinated as part of the WISDEM-based obesity service, and the percentage reduction in body weight was calculated for both groups. In comparison, the two groups were statistically equivalent, with people 60 years and older reducing their body weight by an average of 7.3%, compared with a 6.9% reduction in body weight for those under 60 years of age. Both groups spent similar time in the obesity service, averaging 33.6 months for those aged 60 and over and 41.5 months for those under 60.

\r\n\r\n

\r\n The hospital program only used lifestyle changes tailored to each individual patient, with an emphasis on dietary changes, psychological support, and encouraging physical activity. Most of the patients referred to the obesity service were morbidly obese with BMIs typically greater than 40 kgm-2.
\r\n There are more than 50 comorbidities of obesity that can be reduced while losing weight, including diabetes, psychiatric conditions like depression and anxiety, osteoarthritis, and other mechanical problems. Obesity is also linked to increased mortality and poor well-being.
\r\n The lead author Dr. Thomas Barber of Warwick Medical School at the University of Warwick said, "Weight loss is important at any age, but as we get older we are more likely to develop the weight-related comorbidities of obesity. Many of them are similar to the effects of aging, therefore one could argue that the relevance of weight loss increases with age and we should take this into account.
\r\n "There are a number of reasons why people may devalue weight loss in the elderly. These include an 'ageistic' perspective that weight loss is not relevant to the elderly and misconceptions about the decreased ability of the elderly to lose weight and gain weight through diet changes may feel that hospital obesity services are not for them. Service providers and policy makers should recognize the importance of weight loss in the obese elderly in maintaining health and wellbeing, as well as facilitating healthy aging contribute to clinical decisions regarding the implementation of lifestyle management for older people.
\r\n "Age should not be an obstacle to lifestyle management for obesity. Instead of imposing obstacles on older people who have access to weight loss programs, we should proactively facilitate this process. Otherwise there is a risk of further and unnecessary neglect of older people through social age-related misunderstandings . ""

\r\n","createDate":"2020-12-30T14:40:00","status":1,"picture":"https://cdn.clinicways.com/news/66d2ccae-82f7-45a4-ba70-2a443c5f8310/Main.JPEG","guid":"66d2ccae-82f7-45a4-ba70-2a443c5f8310","newsType":1,"seoUrl":"age-is-not-a-barrier-to-successful-weight-loss-according-to-a-new-study","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"According to a new study by the University of Warwick's NHS Trust and Coventry and Warwickshire University Hospitals (UHCW) that shows that age is not a barrier, obese patients over the age of 60 can lose as much weight as younger people who just make lifestyle changes apply to lose.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":225,"title":"The study examines the remission of an im immit with obesity in teenagers after bariatric surgery","newsContent":"

Eighty to 90% of adolescents benefit from permanent weight loss after bariatric surgery, and most experience remission from obesity-related complications such as high blood pressure, high cholesterol, type 2 diabetes, and musculoskeletal pain. In a new study published in Obesity, researchers at Children's Colorado Children's Hospital showed that remission from obesity-related complications other than cholesterol and triglyceride levels did not depend on major sustained weight loss. Rather, the majority of adolescents benefited from remission from obesity-related complications, an observation that was independent of whether or not they had lost a significant amount of weight.

\r\n\r\n

"We see the results of this study as very encouraging," said Dr. Sarkis Christopher (Chris) Derderian, Pediatric Surgery Fellow at Children's Colorado. "Because the extent of weight loss does not seem to hamper sustained remission of many obesity-related complications, the study supports the myriad benefits of bariatric surgery for severely obese adolescents. These patients may frequently stop taking drugs for type 2 diabetes high blood pressure after surgery. Not only does this dramatically improve the quality of life, but it can also offset the cost of treating such complications over time if the cost of treating such complications is no longer incurred. "

\r\n\r\n

In the study, Derderian and colleagues compared the remission rates of obesity-related complications in two groups of patients: those who lost less than 20% of total body weight five years after surgery and those who lost all of their body weight 20% or more was the same period. All 192 study participants were part of a multicenter study conducted by researchers from Children's Colorado, known as the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS).

\r\n\r\n

In particular, the researchers found that 40.6% of the study participants had a total body weight loss of <20% and 59.4% had a total body weight loss of> 20% after five years. While the latter group saw greater improvement in their cholesterol levels, remission of other complications appeared to be independent of whether or not participants achieved greater sustained weight loss.

\r\n\r\n

"If you look at the relationship between the extent of weight loss and the health benefits achieved, it is clear that patients' health improves, regardless of whether or not they experience significant weight loss in the long term after the operation," said Thomas H. Inge . MD, Ph.D., Principal Researcher at Teen-LABS and Director of Pediatric Surgery and the Bariatric Center in Children's Colorado. "While this study is incredibly promising, additional research is needed to determine whether the same benefits are achieved in patients who experience only five to 10% weight loss over time. Nonetheless, this study supports the recognition of bariatric surgery as the most effective intervention to promote significant and permanent weight loss in adolescents with severe obesity. "

\r\n","createDate":"2020-12-30T14:38:00","status":1,"picture":"https://cdn.clinicways.com/news/f7f2b4b6-3101-4fb2-a7a7-f8233fd5f5ef/Main.JPEG","guid":"f7f2b4b6-3101-4fb2-a7a7-f8233fd5f5ef","newsType":1,"seoUrl":"the-study-examines-the-remission-of-an-im-immit-with-obesity-in-teenagers-after","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Eighty to 90% of adolescents benefit from permanent weight loss after bariatric surgery, and most experience remission from obesity-related complications such as high blood pressure, high cholesterol, type 2 diabetes, and musculoskeletal pain","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":222,"title":"Hormone that shuts off hunger could help fight obesity","newsContent":"

A hormone that can suppress food intake and increase bloating in mice has shown similar results in humans and non-human primates, according to a new study published today in eLife.

\r\n\r\n

The hormone lipocalin-2 (LCN2) could be used as a potential treatment for people with obesity whose natural signals of fullness are no longer working.

\r\n\r\n

LCN2 is mainly produced by bone cells and occurs naturally in mice and humans. Studies in mice have shown that long-term administration of LCN2 to the animals reduces food intake and prevents weight gain without slowing down the metabolism.

\r\n\r\n

"LCN2 is a post-meal satiety signal and causes mice to limit their food intake. It does so by acting on the hypothalamus in the brain," explains lead author Peristera-Ioanna Petropoulou, a postdoctoral fellow at Columbia University's Irving Medical Center, New York, USA, was in the Helmholtz Diabetes Center of the Helmholtz Zentrum München, Munich when the study was carried out. "We wanted to see if LCN2 had similar effects in humans and if a dose of it could cross the blood-brain barrier."

\r\n\r\n

The team first analyzed data from four different studies involving people in the United States and Europe who were either normal, overweight, or obese. Individuals in each study were given a meal after an overnight fast and the amount of LCN2 in their blood before and after the meal was examined. The researchers found that in subjects of normal weight, LCN2 levels increased after eating, which coincided with post-meal satisfaction.

\r\n\r\n

In contrast, LCN2 levels decreased after a meal in people who were overweight or obese. Based on this post-meal response, the researchers grouped people as non-responders or responders. Non-responders who showed no increase in LCN2 after a meal tended to have larger waist sizes and higher markers of metabolic disorders - including BMI, body fat, increased blood pressure, and increased blood sugar. Notably, however, it was found that people who lost weight after gastric bypass surgery had restored sensitivity to LCN2 - which changed their status from non-responders before surgery to responders after.

\r\n\r\n

Taken together, these results mirror those seen in mice and suggest that this post-meal loss of LCN2 regulation is a novel mechanism that contributes to obesity and could be a potential target for weight loss treatments.

\r\n\r\n

After checking whether LCN2 could get into the brain, the team looked at whether treatment with the hormone could reduce food intake and prevent weight gain. To do this, they treated monkeys with LCN2 for one week. They saw a 28% decrease in food intake compared to pre-treatment within a week, and the monkeys also ate 21% less than their saline-only counterparts. In addition, measurements of body weight, body fat and blood lipid levels showed a downward trend in treated animals after only one week of treatment.

\r\n\r\n

"We have shown that LCN2 reaches the brain, reaches the hypothalamus, and suppresses food intake in non-human primates," concludes senior author Stavroula Kousteni, professor of physiology and cell biophysics at Irving Medical Center, Columbia University. "Our results show that the hormone can curb appetite with negligible toxicity and lay the foundation for the next level of LCN2 testing for clinical use."

\r\n","createDate":"2020-12-28T11:37:00","status":1,"picture":"https://cdn.clinicways.com/news/cba171f2-64c8-45a4-aaaa-c12184b222b7/Main.JPEG","guid":"cba171f2-64c8-45a4-aaaa-c12184b222b7","newsType":1,"seoUrl":"hormone-that-shuts-off-hunger-could-help-fight-obesity","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"A hormone that can suppress food intake and increase bloating in mice has shown similar results in humans and non-human primates, according to a new study published today in eLife.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":219,"title":"Does a healthy diet contradict the negative effects of obesity?","newsContent":"

A healthy quality Mediterranean diet partially alters the relationship between obesity and cardiovascular mortality. That's according to a new study published this week in PLOS Medicine by Karl Michaëlsson of Uppsala University, Sweden and colleagues.
\r\n Higher body mass (BMI) caused 4.0 million deaths worldwide in 2015, and more than two-thirds of those deaths were due to cardiovascular disease (CVD). Studies have shown that other factors, including healthy eating habits, could alter the higher risk of CVD associated with a higher BMI. In the new study, the researchers looked at the BMI, diet and mortality of 79,003 Swedish adults who were included in the Swedish mammography cohort and the cohort of Swedish men. Adherence to a Mediterranean Diet (mMED) was rated on a scale from 0 to 8, taking into account information about intake of fruits and vegetables, legumes, nuts, unrefined or high fiber grains, fish, red and processed meat, and olive oil. Information was also available on the age, physical activity, smoking, and socio-economics of the cohort participants.
\r\n Over 21 years of follow-up, 30,389 (38% of participants) died. Among overweight subjects, those with high mMED (HR 0.94; 95% CI 0.90-0.98 compared to subjects of normal weight and high mMED) were the group with the lowest hazard ratio (HR) for all-cause mortality. Overweight subjects with high mMED did not have a significantly higher mortality than subjects with normal weight and high mMED (HR 1.03; 95% CI 0.96-1.11). Conversely, people with a normal BMI but low mMED had a higher mortality (HR 1.60; 95% CI 1.48-1.74) than people with a normal weight and high mMED. For CVD mortality, which accounted for 12,064 deaths, the results were broadly similar. Although the CVD morale associated with high BMI was lowered by following a Mediterranean diet, it was not completely counteracted. In addition, a lower BMI did not counteract the increased CVD mortality associated with a low mMED.
\r\n "These results suggest that following healthy diets such as a Mediterranean diet may be a more appropriate focus than avoiding obesity to prevent all-cause mortality," say the authors. "Even so, a healthy diet cannot fully counteract the higher CVD mortality associated with obesity."

\r\n","createDate":"2020-12-28T11:35:00","status":1,"picture":"https://cdn.clinicways.com/news/93883d09-ccb3-4984-92ff-026152b0b00a/Main.JPEG","guid":"93883d09-ccb3-4984-92ff-026152b0b00a","newsType":1,"seoUrl":"does-a-healthy-diet-contradict-the-negative-effects-of-obesity","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"A healthy quality Mediterranean diet partially alters the relationship between obesity and cardiovascular mortality.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":216,"title":"Avoiding inflammatory foods can lower heart disease and the risk of stroke","newsContent":"

The study further examines the link between inflammation and heart disease through the effects of inflammatory food consumption
\r\n Diets high in red and processed meats, refined grains, and sugary beverages, which have been linked to increased inflammation of the body, can increase the risk of heart disease and stroke later on compared to diets that include anti-inflammatory foods. This is according to a study published today in the Journal of the American College of Cardiology. A separate JACC study assessed the positive effects of consuming walnuts, an anti-inflammatory food, on reducing the risk of inflammation and heart disease.

\r\n\r\n

\r\n Chronic inflammation has been shown to play an important role in the development of heart disease and stroke. Certain inflammatory biomarkers such as interleukins, chemokines, and adhesion molecules have been linked to early and late stages of atherosclerosis. Previous studies have shown that diet can affect inflammation levels, but few have healthy eating habits, such as the Mediterranean diet (high in olive oil, nuts, whole grains, fruits and vegetables, and eating seafood and lightly dairy and red / processed meats) shown lower levels of some inflammatory biomarkers and a lower risk of heart disease. Fewer research has been done on whether long-term adherence to pro-inflammatory diets is linked to increased rates of heart disease or stroke.
\r\n The researchers used the men and women from Nurses' Health Studies I and II from 1986 and included up to 32 years of follow-up. After excluding participants with missing nutritional information or previously diagnosed heart disease, stroke or cancer, over 210,000 participants were included in the analysis. Participants took part in a survey every four years to determine food intake.
\r\n "Using an empirically developed, food-based nutrition index to assess the level of inflammation associated with ingestion, we found that diet patterns with higher inflammation potential were associated with increased rates of cardiovascular disease," said Dr. Jun Li, PhD. Study lead author and research scientist in the Nutrition Department at Harvard TH Chan School of Public Health. "Our study is among the first to link a food-based index of inflammation via diet to long-term risk of cardiovascular disease."

\r\n\r\n

The food-based pro-inflammatory nutrition index is based on 18 pre-defined food groups, which together have the strongest associations with an increase in inflammatory biomarkers. After checking for other risk factors such as BMI, physical activity, family history of heart disease, and multivitamin use, participants who consumed pro-inflammatory diets had a 46% higher risk of heart disease and a 28% higher risk of stroke than those who took anti-inflammatory diets.
\r\n The researchers suggested consuming foods with higher antioxidant and fiber content to fight inflammation: leafy green vegetables (kale, spinach, cabbage, arugula), yellow vegetables (pumpkin, yellow peppers, beans, carrots), whole grains, coffee , Tea and wine. The researchers also suggested limiting your intake of refined sugars and grains, fried foods, sodas and processed meats, red meats and organ meats. These foods make a significant contribution to the pro-inflammatory nutritional index.
\r\n "A better understanding of the health protection of various foods and diets, mainly their anti-inflammatory properties, should lay the foundation for developing even healthier eating habits to protect against heart disease," said Dr. Ramon Estruch, Senior Consultant at the Internal Medicine Department of the Hospital Clinic in Barcelona, Spain, and author of an accompanying editorial comment. "Indeed, when choosing foods in our diet, we should be wary of their anti-inflammatory and anti-inflammatory potential!"

\r\n\r\n

\r\nIncorporating walnuts into your diet reduces inflammation

\r\n\r\n

\r\n In another study, researchers looked at how including walnuts in a person's usual diet would improve inflammatory biomarkers. Previous studies have shown that consuming nuts regularly is linked to a lower risk of heart disease and lower total cholesterol. However, there is limited research linking nut consumption to less inflammation in the body. A total of 634 participants were assigned either a diet without walnuts or a diet with regularly incorporated walnuts (approx. 30-60 grams per day). After a follow-up period of two years, those who ate a diet containing walnuts showed a significantly reduced rate of inflammation in the body in 6 out of 10 of the inflammatory biomarkers tested.
\r\n "The anti-inflammatory effects of long-term walnut consumption demonstrated in this study provides novel mechanistic insights into the benefits of walnut consumption for risk of heart disease beyond that of lowering cholesterol," said Montserrant Cofán, PhD, lead author of the study and a researcher on August Pi i Sunyer Biomedical Research Institute in Barcelona, Spain.

\r\n","createDate":"2020-12-26T15:05:00","status":1,"picture":"https://cdn.clinicways.com/news/10bb318d-ae47-4e6d-9150-909e455ada8f/Main.JPEG","guid":"10bb318d-ae47-4e6d-9150-909e455ada8f","newsType":1,"seoUrl":"avoiding-inflammatory-foods-can-lower-heart-disease-and-the-risk-of-stroke","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"The study further examines the link between inflammation and heart disease through the effects of inflammatory food consumption Diets high in red and processed meats, refined grains, and sugary beverages, which have been linked to increased inflammation of the body, can increase the risk of heart disease and stroke later on compared to diets that include anti-inflammatory foods.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":213,"title":"How could a hormone aid weight loss in obesity?","newsContent":"

Research in humans and monkeys suggests that lipocalin-2 (LCN2), a hormone that plays a role in feeling full after eating a meal, may help with weight loss.
\r\nPrevious studies have shown that mice given LCN2 for a period of time reduce their appetite and body weight, improve their sugar metabolism, and increase energy expenditure.
\r\nA new paper appearing in eLife magazine suggests that the hormone has similar effects in primates such as monkeys and humans. This may mean that LCN2 can help people with obesity lose weight.
\r\nObesity is an increasingly serious health problem worldwide. According to the World Health Organization (WHO), at least 2.8 million people die each year as a result of being obese or overweight.
\r\nThis condition is also linked to other chronic health problems, such as: B. Type 2 diabetes, coronary artery disease, stroke, cancer and depression.
\r\nDoctors usually classify people as obese when they have a body mass index (BMI) of 25 or greater, and they tend to classify people as obese when they have a BMI of 30 or greater.
\r\nIt is currently difficult to reduce obesity because of the limited understanding of the body's mechanisms by which to maintain a balance between weight, energy intake, and energy expenditure.
\r\nFor example, when people who have been obese for a long time lose weight, their body slows down their metabolism, which can ultimately lead to weight gain.
\r\nIn general, diet and exercise programs for weight loss tend to be short-term, while known pharmacological therapies raise safety concerns and have limited effectiveness.
\r\nThe lead study author Dr. Peristera-Ioanna Petropoulou and colleagues believe that further research on LCN2 may lead to a new way of reducing obesity.
\r\nDuring the study, Dr. Petropoulou is a postdoctoral fellow at Columbia University's Irving Medical Center in New York City, NY. She is now a member of the Helmholtz Diabetes Center in the Helmholtz Center Munich in Germany.
\r\n“LCN2 acts as a signal for feeling full after a meal and causes mice to limit their food intake. It does this by acting on the hypothalamus in the brain. We wanted to find out whether LCN2 has similar effects in humans and whether a dose of it can cross the blood-brain barrier. "
\r\n- Dr. Peristera-Ioanna Petropoulou

\r\n\r\n

\r\n How does LCN2 work?

\r\n\r\n

\r\nLCN2 is a hormone that is produced in the bone cells of mammals, including humans.
\r\nThe study's authors analyzed data from four previous studies that included people of "normal weight", people who were overweight, people who were obese, and people who were severely obese. These showed that the concentration of LCN2 in the blood of people of normal weight increased after eating.
\r\nIt peaks around 45 to 60 minutes after eating, and during the same period, people's hunger tends to decrease.
\r\nSome overweight people had smaller initial increases in LCN2 levels, followed by a decrease, and their feeling of fullness after eating a meal was reduced.
\r\nThe LCN2 levels of people with obesity decreased after eating. As a result, researchers believe that regulating LCN2 may be key to understanding, and possibly reducing, obesity.

\r\n\r\n

LCN2 in mice and monkeys

\r\n\r\n

\r\n Previous research has shown that injection of LCN2 into lean mice and those with obesity decreased their appetite by activating receptors in the hypothalamus. This is a part of the brain that is responsible for feeling hungry and full.
\r\nResearchers have identified mutations in the receptors that LCN2 works on as a common cause of obesity.
\r\nLCN2 works in mice by crossing the blood-brain barrier. This is a barrier created by the unique properties of the smallest blood vessels in the central nervous system. Its job is to regulate which molecules can get into the brain from the bloodstream.
\r\nIt ensures that the brain receives the molecules it needs to function, and it also acts as a barrier that protects the brain from pollutants.
\r\nThe new study suggests that LCN2 is able to cross the blood-brain barrier and bind to the hypothalamus in monkeys. This can mean that it works the same way in humans.
\r\n"We have shown that LCN2 reaches the brain, reaches the hypothalamus and suppresses food intake in non-human primates," says lead study author Prof. Stavroula Kousteni.
\r\nThe study also suggests that like mice, monkeys' appetites decrease when given LCN2.
\r\nIn the study, one group of monkeys received LCN2 and another group received saline for one week. The food consumption of the monkeys treated with LCN2 decreased by 27%, while it decreased by 25% in the monkeys that received the saline solution.
\r\nThe researchers also observed weight loss over a short period of time. However, other observed metabolic parameters did not change significantly.
\r\nHowever, due to the small number of monkeys involved in the study, more research is needed to definitively prove the results.
\r\n Is it safe?
\r\nAn important question of the study was whether or not the administration of LCN2 to primates had dangerous side effects.
\r\nResearchers regularly collected and analyzed blood samples from monkeys and looked for the usual indicators of liver and kidney damage or toxicity. However, they did not find any significant changes in these markers.
\r\nThis suggests that LCN2 is a surefire way to reduce feelings of hunger. As a result, it can have the potential to become a new method for achieving and maintaining weight loss.
\r\nThe study's authors believe that more, more extensive research is needed on how BMI, food composition, and other factors affect the response to LCN2 in humans.
\r\nHowever, these initial results suggest that scientists in the future may develop an LCN2-based intervention to safely reduce overweight and obesity.
\r\n"Our results show that the hormone can curb appetite with negligible toxicity and lay the foundation for the next stage of LCN2 tests for clinical use," concludes Prof. Kousteni

\r\n","createDate":"2020-12-26T14:10:00","status":1,"picture":"https://cdn.clinicways.com/news/c6691ae3-02cd-4a63-aeb6-1170bbc4b373/Main.JPEG","guid":"c6691ae3-02cd-4a63-aeb6-1170bbc4b373","newsType":1,"seoUrl":"how-could-a-hormone-aid-weight-loss-in-obesity","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Research in humans and monkeys suggests that lipocalin-2 (LCN2), a hormone that plays a role in feeling full after eating a meal, may help with weight loss.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":210,"title":"New link between gut bacteria and obesity","newsContent":"

Researchers at Lund University in Sweden have discovered a new link between gut bacteria and obesity. They found that certain amino acids in our blood may be linked to both obesity and the composition of the gut microbiome.

\r\n\r\n

We know less about the importance of our intestinal bacteria than many books and magazines on the subject would suggest. Much of the research on this topic is based on animal testing, which cannot be directly applied to humans. A healthy intestinal flora for one person does not necessarily have to be good for another person.

\r\n\r\n

However, an increasing number of research studies show that our gut microbiota play an important role in our health. It affects our metabolism and can be linked to obesity, cardiovascular disease, and type 2 diabetes.

\r\n\r\n

Previous studies have shown that people with these diseases have different metabolites; H. Small molecules, or metabolic debris, appear differently in the bloodstream. The aim of the new study was therefore to identify metabolites in the blood that can be associated with obesity (high body mass index, BMI) and to investigate whether these metabolites associated with obesity influence the composition of the bacterial flora in stool samples .

\r\n\r\n

The researchers analyzed blood plasma and stool samples from 674 participants in the Malmö Offspring Study, MOS. They found 19 different metabolites that could be linked to the person's BMI. Glutamate and so-called BCAA (branched-chain and aromatic amino acids) had the strongest association with obesity.

\r\n\r\n

They also found that the obesity-related metabolites were linked to four different gut bacteria (Blautia, Dorea, and Ruminococcus in the Lachnospiraceae and SHA98 family).

\r\n\r\n

"The differences in BMI were largely explained by the differences in glutamate and BCAA levels. This shows that the metabolites and gut bacteria interact instead of being independent," says Marju Orho-Melander, professor of genetic epidemiology at Lund University .

\r\n\r\n

By far the strongest risk factor for obesity in the study, glutamate, has been linked to obesity in previous studies, and BCAA was used to predict the future occurrence of type 2 diabetes and cardiovascular disease.

\r\n\r\n

"This means that future studies should focus more on how the makeup of gut bacteria can be changed to reduce the risk of obesity and related metabolic and cardiovascular diseases," says Marju Orho-Melander. "To get there, we first need to understand what a healthy normal gut flora looks like and what factors affect bacterial composition. This requires extensive population studies such as the Malmö Progeny Study and intervention studies," she concludes.

\r\n","createDate":"2020-12-23T21:38:00","status":1,"picture":"https://cdn.clinicways.com/news/093719b5-34ff-44af-b28c-7f1138f41460/Main.JPEG","guid":"093719b5-34ff-44af-b28c-7f1138f41460","newsType":1,"seoUrl":"new-link-between-gut-bacteria-and-obesity","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Researchers at Lund University in Sweden have discovered a new link between gut bacteria and obesity.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":207,"title":"Latest findings on obesity and COVID-19","newsContent":"

A summary of what is known to date suggests that obesity is associated with a higher risk of developing severe symptoms and complications of Coronavirus Disease 19 (COVID-19), regardless of other diseases such as cardiovascular disease.

\r\n\r\n

All data and statistics are based on publicly available data at the time of publication. Some information may be out of date. Visit our Coronavirus Hub and follow our live update page for the latest information on the COVID-19 outbreak.

\r\n\r\n

Early data seems to suggest that people with obesity are more likely to get seriously ill due to COVID-19, the disease caused by the novel coronavirus.

\r\n\r\n

An increasing number of reports have linked obesity to coronavirus mortality, and the Centers for Disease Control and Prevention (CDC) are now listing severe obesity as a risk factor for severe COVID-19. The CDC defines severe obesity as having a body mass index (BMI) of 40 or higher.

\r\n\r\n

However, it is currently unclear why obesity is linked to a more dangerous form of the disease.

\r\n\r\n

To shed light on the situation, a team of experts in Germany, the UK and the US have come together to review the evidence and clarify what we know so far.

\r\n\r\n

Their results are published in Nature Reviews Endocrinology.

\r\n\r\n

Stay up to date with the current COVID-19 outbreak with live updates and visit our Coronavirus Hub for more advice on prevention and treatment.

\r\n\r\n

The evidence so far

\r\n\r\n

The article summarizes the preliminary data on obesity and COVID-19.

\r\n\r\n

In China, where the outbreak began, data from 383 patients showed obesity was linked to a 142% higher risk of developing severe pneumonia-related COVID-19.

\r\n\r\n

A larger study of over 4,000 patients with COVID-19 in New York City found that being severely overweight by age is a major risk factor for hospitalization.

\r\n\r\n

In Seattle, a study of critically ill COVID-19 patients found similar results. This analysis found that 85% of obese patients required mechanical ventilation compared with 64% of patients without the condition. Additionally, 62% of obese patients died from COVID-19 compared to 36% of non-obese patients.

\r\n\r\n

It is important to note, however, that this particular study included only 24 patients, all of whom were critically ill, making it difficult to draw far-reaching conclusions from the data.

\r\n\r\n

The final study included in the analysis, which included 124 patients in Lille, France, also found that obese patients were more likely to require invasive mechanical ventilation.

\r\n\r\n

Taken together, the evidence suggests that obesity can be a significant risk factor for COVID-19.

\r\n\r\n

As the lead author of the study, Dr. Norbert Stefan from the German Center for Diabetes Research Medical News Today:

\r\n\r\n

"We have come to the conclusion that obesity puts people infected with the novel coronavirus (SARS-CoV-2) at a very high risk of more severe COVID-19 disease and potentially a risk of death."

\r\n\r\n

Why is Obesity a Risk Factor?

\r\n\r\n

Importantly, the risk seems to be independent of other diseases such as high blood pressure, which are more common in people with obesity.

\r\n\r\n

According to the study's authors, a possibility that obesity may increase the risk of severe COVID-19 is a breathing disorder.

\r\n\r\n

People with obesity are more likely to have higher resistance in their airways, lower lung volume, and weaker breathing muscles, which are critical to fighting off COVID-19. These factors make a person more likely to develop pneumonia and put additional stress on the heart.

\r\n\r\n

Obesity is also linked to diabetes, heart disease, and kidney disease, which also increase the risk of pneumonia.

\r\n\r\n

Aside from these issues, high blood pressure, high cholesterol, and prediabetes could make people more susceptible to infection, the authors said.

\r\n\r\n

The link between diabetes and COVID-19 appears to be particularly important.

\r\n\r\n

"There is data showing that hyperglycemia [high levels of glucose in the blood] is a strong and independent predictor of severe COVID-19 progression, even in the undiagnosed area," explains Dr. Stefan.

\r\n\r\n

Missing BMI data

\r\n\r\n

While this research strongly suggests that obese people are at higher risk associated with COVID-19, there are limitations to its analysis. First, most studies have not yet been peer-reviewed.

\r\n\r\n

Many also failed to provide measurements of patient weight or height, both of which are required to calculate BMI, a universal measure of obesity. The BMI can also be used to estimate the percentage of body fat.

\r\n\r\n

"Most of the articles published in the past 2 months that included data on comorbid conditions that may be associated with an increased risk of severe COVID-19 did not provide data on body fat mass or metabolic health," says Dr. Stefan. In particular, some studies from China and Lombardy, Italy - two of the hardest hit areas - did not provide any weight or size information.

\r\n\r\n

The authors emphasize that future studies should record not only BMI, but waist circumference as well as glucose levels and the hormone that regulates it, insulin. These measurements can help determine if a person has insulin resistance or prediabetes, which may contribute to a higher risk of COVID-19 in people who are obese.

\r\n","createDate":"2020-12-23T21:28:00","status":1,"picture":"https://cdn.clinicways.com/news/b78ab2be-05c5-4d52-9edb-e6e7801f6ad4/Main.JPEG","guid":"b78ab2be-05c5-4d52-9edb-e6e7801f6ad4","newsType":1,"seoUrl":"latest-findings-on-obesity-and-covid-19","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"A summary of what is known to date suggests that obesity is associated with a higher risk of developing severe symptoms and complications of Coronavirus Disease 19 (COVID-19), regardless of other diseases such as cardiovascular disease.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":204,"title":"What is Obesity and What Causes It?","newsContent":"

Obesity is a disease that occurs when a person carries excess weight or body fat that could affect their health. A doctor will usually suggest that a person is obese if they have a high body mass index.

\r\n\r\n

The Body Mass Index (BMI) is a tool that doctors can use to assess whether a person is of an appropriate weight for their age, gender, and height. The measurement combines height and weight.

\r\n\r\n

A BMI between 25 and 29.9 indicates that a person is overweight. A BMI of 30 or more suggests that a person may have obesity.

\r\n\r\n

Other factors such as the waist to hip ratio (WHR), the waist to height ratio (WtHR), and the amount and distribution of fat on the body also play a role in determining the weight and health of a person's body shape.

\r\n\r\n

When a person is obese and overweight, it can increase their risk of developing a number of health conditions, including metabolic syndrome, arthritis, and some types of cancer.

\r\n\r\n

Metabolic syndrome encompasses a number of issues such as high blood pressure, type 2 diabetes, and cardiovascular disease.

\r\n\r\n

Maintaining a healthy weight or losing weight through diet and exercise is one way to prevent or reduce obesity. In some cases, a person may need surgery.

\r\n\r\n

Now read on to find out why obesity occurs.

\r\n\r\n

1) Consume too many calories

\r\n\r\n

\r\nWhen a person is consuming more calories than they are consuming for energy, their body stores the extra calories as fat. This can lead to overweight and obesity.

\r\n\r\n

Also, some types of foods are more likely to make you gain weight, especially those high in fats and sugars.

\r\n\r\n

Foods that increase your risk of weight gain include:

\r\n\r\n

Fast food
fried foods such as french fries
fatty and processed meat
lots of dairy products
Foods with added sugar such as baked goods, ready-made breakfast cereals, and cookies
Foods that contain hidden sugars, such as ketchup and many other canned and packaged foods
sweetened juices, lemonades and alcoholic beverages
processed, high-carbohydrate foods like bread and bagels
Some processed foods contain high fructose corn syrup as a sweetener, including savory products like ketchup.

\r\n\r\n

Eating too much of these foods and too little exercise can lead to weight gain and obesity.

\r\n\r\n

A person on a diet consisting primarily of fruits, vegetables, whole grains, and water is still at risk of gaining excess weight if they overeat or if, for example, genetic factors increase their risk.

\r\n\r\n

However, they are more likely to have a varied diet while maintaining a healthy weight. Fresh foods and whole grains contain fiber, which makes a person feel full longer and promotes healthy digestion.

\r\n\r\n

2) Lead a sedentary lifestyle

\r\n\r\n

\r\nMany people lead a much more sedentary lifestyle than their parents and grandparents.

\r\n\r\n

Examples of sedentary habits are:

\r\n\r\n

work in an office instead of doing manual labor
Play games on a computer instead of engaging in physical activity outside
drive to places instead of walking or cycling
The less a person moves, the fewer calories they burn.
In addition, physical activity affects how a person's hormones work, and hormones affect how the body processes food.
Several studies have shown that physical activity can help keep insulin levels stable, and that unstable insulin levels can lead to weight gain.

\r\n\r\n

Researchers who published a report in BMJ Open Sport and Exercise Medicine in 2017 found that the designs of some studies make it difficult to draw precise conclusions: "A lifestyle that included regular [physical activity] has become a key factor in maintaining it and improving many aspects of health, including insulin sensitivity. "

\r\n\r\n

Physical activity doesn't have to be done in the gym. Physical work, walking or cycling, climbing stairs, and household chores all contribute to this.

\r\n\r\n

However, the type and intensity of activity can affect the extent to which it benefits the body in the short and long term.

\r\n\r\n

3) Not getting enough sleep

\r\n\r\n

\r\nResearch has shown that a lack of sleep increases the risk of weight gain and developing obesity.

\r\n\r\n

The researchers reviewed evidence from over 28,000 children and 15,000 adults in the UK from 1977 to 2012. In 2012, they concluded that sleep deprivation significantly increased the risk of obesity in both adults and children.

\r\n\r\n

The changes affected children as young as 5 years old.

\r\n\r\n

The team suggested that sleep deprivation can lead to obesity as it can lead to hormonal changes that increase appetite.

\r\n\r\n

When a person doesn't get enough sleep, their body makes ghrelin, a hormone that stimulates appetite. At the same time, a lack of sleep also leads to lower production of leptin, a hormone that suppresses appetite.

\r\n\r\n

4) Endocrine Disruptors

\r\n\r\n

\r\nA team from the University of Barcelona published a study in the World Journal of Gastroenterology that suggests how liquid fructose - a type of sugar - in beverages can alter lipid metabolism and lead to fatty liver and metabolic syndrome.

\r\n\r\n

Metabolic syndrome features include diabetes, cardiovascular disease, and high blood pressure. Obese people are more likely to have metabolic syndrome.

\r\n\r\n

After feeding the rats a 10 percent fructose solution for 14 days, the scientists found that their metabolism gradually changed.

\r\n\r\n

Scientists believe there is a link between high fructose consumption and obesity and metabolic syndrome. Authorities have raised concerns about using high-fructose corn syrup to sweeten beverages and other foods.

\r\n\r\n

Animal studies have shown that obesity due to fructose consumption is also closely related to type 2 diabetes.

\r\n\r\n

In 2018, the researchers published the results of studies on young rats. They too experienced metabolic changes, oxidative stress and inflammation after consuming fructose syrup.

\r\n\r\n

The researchers state that "increased fructose intake may be an important predictor of metabolic risk in young people".

\r\n\r\n

They are calling for changes in young people's diets to prevent these problems.

\r\n\r\n

Avoid high fructose corn syrup

\r\n\r\n

Foods that contain high fructose corn syrup include:

\r\n\r\n

Lemonades, energy drinks and sports drinks
Candy and ice cream
Coffee cream
Sauces and condiments, including salad dressings, ketchup and barbecue sauce
sweetened foods like yogurt, juices, and canned foods
Bread and other ready-made baked goods
Breakfast cereals, granola bars, and energy or nutritional bars
How to reduce your intake of corn syrup and other additives:
Check the labels before buying
If possible, opt for unsweetened or less processed items
Prepare salad dressings and bake other products at home
Some foods contain other sweeteners, but these can also have adverse effects.

\r\n\r\n

5) Medication and weight gain

\r\n\r\n

\r\nSome medications can also cause weight gain.

\r\n\r\n

The results of a review and meta-analysis published in the Journal of Clinical Endocrinology and Metabolism in 2015 found that some drugs caused people to gain weight over a period of months.

\r\n\r\n

atypical antipsychotics, especially olanzapine, quetiapine, and risperidone
Anticonvulsants and mood stabilizers, especially gabapentin
hypoglycemic drugs such as tolbutamide
Glucocorticoids, used to treat rheumatoid arthritis
some antidepressants

\r\n\r\n

However, some drugs can cause weight loss. Anyone taking a new drug and worried about their weight should ask their doctor whether the drug is likely to have an impact on their weight.

\r\n\r\n

6) Is Obesity Self-Persistent?

\r\n\r\n

\r\nThe longer a person is overweight, the more difficult it can be for them to lose weight.

\r\n\r\n

The results of a mouse study published in the journal Nature Communications in 2015 suggest that the more fat a person carries, the less likely the body is to burn fat due to a protein or gene known as sLR11.

\r\n\r\n

It seems that the more fat a person has, the more SLR11 their body will produce. The protein blocks the body's ability to burn fat, making it harder to lose the extra weight.

\r\n\r\n

7) Obesity gene

\r\n\r\n

\r\nA faulty gene known as the fat mass and obesity-associated gene (FTO) is responsible for some cases of obesity.

\r\n\r\n

A study published in 2013 suggests a link between this gene and:

\r\n\r\n

obesity
Behaviors That Lead to Obesity
higher food intake
a preference for high calorie foods
an impaired ability to feel full known as satiety

\r\n\r\n

The hormone ghrelin plays a crucial role in eating behavior. Among other things, ghrelin affects the release of growth hormones and the way the body accumulates fat.

\r\n\r\n

The activity of the FTO gene can affect a person's likelihood of suffering from obesity as it affects the amount of ghrelin a person has.

\r\n\r\n

In a study of 250 people with eating disorders published in Plos One in 2017, the researchers suggested that aspects of the FTO could also play a role in conditions such as binge eating and emotional eating.

\r\n\r\n

\r\n","createDate":"2020-12-23T01:36:00","status":1,"picture":"https://cdn.clinicways.com/news/6330afb5-d9cc-4054-a1f9-8e8f98005afd/Main.JPEG","guid":"6330afb5-d9cc-4054-a1f9-8e8f98005afd","newsType":1,"seoUrl":"what-is-obesity-and-what-causes-it","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Obesity is a disease that occurs when a person carries excess weight or body fat that could affect their health. A doctor will usually suggest that a person is obese if they have a high body mass index.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":201,"title":"Pediatricians: Risk of infection with SARS-CoV-2 in daycare centers and schools is low","newsContent":"

Berlin - According to a current analysis by paediatricians, the risk of corona infection in daycare centers and schools may be lower than assumed. This is shown by data from more than 110,000 children. Pediatricians from hospitals in Passau, Munich and Regensburg had routinely tested children and adolescents for SARS-CoV-2.

\r\n\r\n

The results were available in advance to the Passauer Neue Presse. Accordingly, as of November 18, an average of only 0.53 percent of minors were infected. Since children often did not show any symptoms, the debate so far has often assumed that the infection rate among children and adolescents is significantly higher than the official statistics reflect.

\r\n\r\n

"It is precisely this assumption that you now have to question," said the head physician at the Passau Children's Clinic, Matthias Keller. In the opinion of the doctors, the analysis comes “closest to a random sample”, since the majority of young patients went to a clinic because of other illnesses or injuries.

\r\n\r\n

These figures support a new statement by the German Academy for Pediatric and Adolescent Medicine, the German Society for Hospital Hygiene and others, since it makes sense medically, infectiously and socially to keep the facilities open with the recommended hygiene measures.

\r\n\r\n

"The responsibility rests with parents, carers, teachers and the entire adult population to protect their children and adolescents from infection and to enable them to visit community facilities through their hygiene-conscious behavior", according to the professional associations.

\r\n\r\n

According to the societies, the school and daycare closings in spring have shown that day care centers, kindergartens and schools are of systemic importance for the psychosocial and psychomotor development of children and adolescents as well as their safety and integrity.

\r\n\r\n

They are also important so that parents can do their jobs. Community facilities must therefore be kept functional for as long as possible by consistently adhering to the hygiene rules.

\r\n","createDate":"2020-11-24T11:13:00","status":1,"picture":"https://cdn.clinicways.com/news/3d8cdb19-9afd-4e9c-8349-8de6c26a7762/Main.JPEG","guid":"3d8cdb19-9afd-4e9c-8349-8de6c26a7762","newsType":1,"seoUrl":"pediatricians-risk-of-infection-with-sars-cov-2-in-daycare-centers-and-schools","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Berlin - According to a current analysis by paediatricians, the risk of corona infection in daycare centers and schools may be lower than assumed. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":198,"title":"Digital competence is becoming a daily tool for doctors","newsContent":"

Berlin - Knowledge about the opportunities and risks of digital applications will be just as essential for doctors in the future as knowledge about drugs. This became clear at a conference of the Standing Committee of European Doctors (French: Comite Permanent des Medecins Europeens, CPME).

\r\n\r\n

Unfortunately, the discussion about digital medicine is too often reduced to purely technical aspects. It is at least as important to talk about the ethical limits and the future role of doctors in digital health care, ”said Klaus Reinhardt, President of the German Medical Association, in his opening address

\r\n\r\n

"Digitization is increasingly a reality in health systems across Europe," said CPME President Frank Ulrich Montgomery. It must therefore be ensured that it is "responsible, positive and well thought out".

\r\n\r\n

As with drugs, it is essential that doctors have at least a rough idea of how it works, the expected result and the possible risks of digital applications.

\r\n\r\n

They would need that in order to be able to take responsibility for the treatment with digital aids. Medical associations and associations of statutory health insurance physicians should offer more advanced training courses on digital applications, advised Montgomery.

\r\n\r\n

The correct handling of programs that could support decision-making through artificial intelligence (AI), for example, must also become an integral part of medical training, warned Lina Mosch from the European Medical Students' Association (EMSA).

\r\n\r\n

The patient commissioner of the federal government, Claudia Schmidke (CDU), emphasized how important it is that patients trust the digital innovations. This must always remain voluntary and should not lead to disadvantages in treatment for patients who refuse digital medicine.

\r\n","createDate":"2020-11-23T18:43:00","status":1,"picture":"https://cdn.clinicways.com//news/1fe07b9f-ee13-4453-9102-19574b841416/Main.JPEG","guid":"1fe07b9f-ee13-4453-9102-19574b841416","newsType":1,"seoUrl":"digital-competence-is-becoming-a-daily-tool-for-doctors","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Berlin - Knowledge about the opportunities and risks of digital applications will be just as essential for doctors in the future as knowledge about drugs. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":195,"title":"Countries continue to negotiate on a common corona strategy","newsContent":"

Berlin - The federal states are continuing to discuss a joint and longer-term strategy in the corona crisis. There had already been several rounds on the weekend. The federal states intend to agree on a joint proposal that will be decided with Merkel the day after tomorrow.

\r\n\r\n

The first plans are summarized in a draft resolution that is available to the Deutsches Ärzteblatt. In it, the countries have outlined their further line. Relaxation is therefore currently not foreseeable - on the contrary, stricter rules will apply from December, as can be seen from the draft resolution.

\r\n\r\n

In principle, the currently applicable measures are to be retained until December 20th. This applies to the closure of restaurants, cinemas and fitness studios, for example. Citizens should continue to stay at home if possible and also work there and refrain from traveling and excursions.

\r\n\r\n

With an incidence of less than 35 new infections per week per 100,000 inhabitants, the federal states should be allowed to relax independently. After December 20, the measures are to be extended every two weeks if the situation does not improve. Countries with an incidence below 50 should then be able to decide independently.

\r\n\r\n

From December 1, 2020 to January 17, 2021 - with intermediate rules for Christmas and possibly the turn of the year - private meetings should be limited to two households and a maximum of five people, with the exception of children under 14 years of age.

\r\n\r\n

In publicly accessible buildings, buses and trains as well as in heavily frequented places in the open, where people stay in confined spaces or for longer periods, a general mask requirement should apply.

\r\n\r\n

Over Christmas - from December 21st to at least 27th - people from more than two households should be able to come together. It is still unclear whether there will be five or ten at a time. Children under the age of 14 should not count.

\r\n\r\n

Self-quarantine for several days is recommended for the period after the holidays. Agreements for the upcoming celebrations should be made with the churches. The guideline should be that large church services are to be avoided.

\r\n\r\n

Banning of firecrackers planned
\r\nIt also seems unclear whether New Year's Eve celebrations with five or ten people from more than two households are possible this year. The resolution proposal provides in brackets that the Christmas rules may apply until January 3rd - there is still no agreement on this.

\r\n\r\n

In the submission, employers are asked to check whether business premises can be closed either due to company holidays or generous home office solutions from December 21, 2020 to January 3, 2021 in order to be able to implement the principle of staying at home nationwide.

\r\n\r\n

It is already clearly stated that there should be no fireworks. Selling, buying and even igniting should be prohibited in order to relieve the emergency services, not to burden the health system further and to avoid group formation.

\r\n\r\n

New regulations are also being considered in schools. If the incidence is over 50, it should be mandatory to wear a mask in class from the seventh grade onwards. Infection-free schools should be able to be excluded from this.

\r\n\r\n

The federal states should decide for themselves about homeschooling. In addition, a new test strategy is planned: In the event of an infection in a class, students and teachers should be quarantined for five days and then run rapid tests. The federal government should make the tests available to the federal states.

\r\n\r\n

aerzteblatt.de

\r\n\r\n

Partial lockdown: Countries reportedly want extension to December 20
\r\nCorona measures: Controversial federal-state talks
\r\nCoronademo: Massive attacks on police officers
\r\nAccording to the proposed resolution, state aid for companies, the self-employed and associations affected by the closure should be extended. For areas that are expected to have major restrictions on business operations for months to come, the federal states are calling for the federal government to extend the bridging aid until mid-2021 - for example for the cultural and event industry, self-employed individuals and the travel industry. The federal government should also examine tax subsidies for statutory health insurance.

\r\n\r\n

The goal of the measures was formulated by Berlin's Governing Mayor Michael Müller (SPD) yesterday evening in the ZDF's “heute journal”. "We want to record various steps at least in phases up to Christmas time, then over Christmas and New Year's Eve [...] well into January," said Müller.

\r\n\r\n

They want to avoid having to make new decisions from week to week and always taking new measures. "And there is also a proposal for this that is now much longer-term than what we had before," said Müller, who is currently chairman of the conference of prime ministers.

\r\n","createDate":"2020-11-22T11:28:00","status":1,"picture":"https://cdn.clinicways.com/news/5b72d9a4-292e-452e-8615-8ad897d86537/Main.JPEG","guid":"5b72d9a4-292e-452e-8615-8ad897d86537","newsType":1,"seoUrl":"countries-continue-to-negotiate-on-a-common-corona-strategy","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Berlin - The federal states are continuing to discuss a joint and longer-term strategy in the corona crisis. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":192,"title":"Greens distance themselves from homeopathy","newsContent":"

The Greens have found a solution to their protracted dispute over homeopathy. On Sunday, the party congress approved a formulation according to which only services from the statutory health insurances should be taken over, "which are medically sensible and justified and whose effectiveness has been scientifically proven". In doing so, the Greens distance themselves from homeopathy as a health insurance benefit - even if the controversial healing method is not expressly mentioned in the text.

\r\n\r\n

However, no majority found an even more extensive formulation according to which services whose effectiveness beyond the placebo effect has not been scientifically proven should be explicitly excluded as health insurance benefits.

\r\n\r\n

The delegates also rejected an amendment proposed by the homeopathic proponents, which should enable the costs to be covered. The Greens had been discussing this question intensively and controversially for a long time. Federal Managing Director Michael Kellner spoke of a “not very easy process” before the vote.

\r\n","createDate":"2020-11-21T12:19:00","status":1,"picture":"https://cdn.clinicways.com/news/dc250b86-9915-4bfb-8140-8d149cd3014a/Main.JPEG","guid":"dc250b86-9915-4bfb-8140-8d149cd3014a","newsType":1,"seoUrl":"greens-distance-themselves-from-homeopathy","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"According to the will of the Greens, health insurance companies should only take over services \"whose effectiveness has been scientifically proven\". The homeopathy compromise was preceded by a “not very easy process”.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.faz.net/aktuell/gesellschaft/gesundheit/parteitag-gruene-gehen-auf-distanz-zu-homoeopathie-17065254.html","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":189,"title":"Orange Juice Against High Blood Pressure ","newsContent":"

The Geisenheim University of Applied Sciences is playing a key role in a Franco-German study that aims to research over a period of two years how herbal remedies work against high blood pressure. Specifically, it is about whether the regular consumption of orange juice can help maintain normal blood pressure and strengthen the cardiovascular system, as the university reports. Research partners are the University Clinic in Clermont-Ferrand and the French Institute for Agronomic Research there.

\r\n\r\n

\r\nIn the course of the Franco-German study, healthy but risk-prone adults were given either a small glass of orange juice or one of two placebo drinks developed in Geisenheim for the first time for six weeks. Pure hesperidin from oranges is added to one of the two placebo soft drinks in addition to a sugar content that is the same as that of orange juice. This is to find out whether the observed health effects are causally attributable to this substance. The short and medium-term effects on the cardiovascular system and changes in the composition of colon bacteria are researched.

\r\n\r\n

\r\nThe Geisenheim Institute Director for Analysis and Technology of Plant Foods, Ralf Schweiggert, will accompany the study together with the Geisenheim polyphenol expert Christof Steingaß. According to the information, Schweiggert hopes that, once the study has been completed, he will be able to explain even better why a balanced diet rich in fruit and vegetables is beyond doubt healthy. Precisely because orange juice is often criticized for its high sugar content, there is an urgent need to find out more about the health effects of this complex mixture of vitamins, minerals and polyphenols.

\r\n","createDate":"2020-11-20T14:33:00","status":1,"picture":"https://cdn.clinicways.com/news/d8c0a5fd-95cd-4682-b21f-e15c947612de/Main.JPEG","guid":"d8c0a5fd-95cd-4682-b21f-e15c947612de","newsType":1,"seoUrl":"orange-juice-against-high-blood-pressure","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"The University of Geisenheim is researching in a Franco-German study whether orange juice can help against high blood pressure. Studies to date are promising.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.faz.net/aktuell/gesellschaft/gesundheit/deutsch-franzoesische-studie-mit-orangensaft-gegen-bluthochdruck-17065840.html","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":186,"title":"Scientists are looking for better concepts of care after bariatric surgery","newsContent":"

Hamburg - The innovation fund of the Federal Joint Committee (G-BA) supports a new health care research project for better aftercare for obese patients after bariatric operations.
\r\nThe consortium leader is DAK-Gesundheit. Other partners are the Leibniz Institute for Prevention Research and Epidemiology in Bremen and the Dresden-Neustadt Municipal Clinic. Almost one million euros are available for the project called “Effects after Bariatric Operations” (ABARO).
\r\nIf morbid obesity cannot be contained with conservative measures, surgical intervention is often carried out, usually a gastric band or gastric bypass is placed. According to the DAK, obese patients often do not receive the necessary aftercare after this bariatric operation.
\r\n"Long-term successes and improvements in the quality of life of the patients could therefore not materialize," the health insurance company said. On the one hand, the research project aims to identify the specific problems in postoperative care. On the other hand, it should provide recommendations and solutions for a higher effectiveness of the treatment, which can serve as the basis for a new care concept.
\r\n"When it comes to obesity, we have to make the health system fit for the future, because in Germany there is a clear under-supply and inadequate supply in the treatment of extreme overweight," said Andreas Storm, CEO of DAK-Gesundheit. The promotion of ABARO by the innovation fund is therefore an important step towards better care for affected patients.

\r\n\r\n

\r\nThe scientists are planning, among other things, a survey of those affected to determine the course of treatment, aftercare services and accompanying and secondary illnesses over several years. “What pain and limitations did the patients have?” “How is the use of dietary supplements and how has the quality of life developed?” Are some of the questions that should be addressed.

\r\n","createDate":"2020-08-30T09:50:00","status":1,"picture":"https://cdn.clinicways.com/news/d2585e4b-8f4f-4780-b439-faab1ff81784/Main.JPEG","guid":"d2585e4b-8f4f-4780-b439-faab1ff81784","newsType":1,"seoUrl":"scientists-are-looking-for-better-concepts-of-care-after-bariatric-surgery","author":null,"categoryid":6,"mainCategoryid":0,"categoryName":"Saç Ekimi","shortDescription":"Hamburg - The innovation fund of the Federal Joint Committee (G-BA) supports a new health care research project for better aftercare for obese patients after bariatric operations.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-hair","categorycolor":"d94da6","language":"En","newsList":[],"doctors":[]},{"newsid":183,"title":"Health insurance companies too hesitant","newsContent":"

The reason: Outpatient offers are still only hesitantly supported by health insurance companies. As a result, many providers have already withdrawn from this segment, reports Wiegand. “We need training courses for young children and their families across Germany. The guideline emphasizes that all concerned should be given access to a training program. This also applies to rural areas, where the prevalence of obesity is higher than in the city.

\r\n\r\n

Martin Wabitsch, one of the lead authors of the new guideline, however, points out: “The success rate for adolescents with extreme obesity is significantly lower than for younger children. For this special group of young patients we need new therapy concepts ”.

\r\n\r\n

DGKJ President Ingeborg Krägeloh-Mann added: "The extensive Cochrane analysis [...] now provides decision-makers with well-founded, science-based recommendations." Because the newly published guideline makes it clear: Obesity is the result of our society's lifestyle.

\r\n\r\n

And "the current mechanisms with which overweight and obesity are countered at the population level are [...] still inadequate and in some cases inadequate," the guideline authors concluded. For children to grow up healthily, far-reaching changes are required, for which strong political support is required.

\r\n\r\n

The pediatrician plays an important role in collaboration with other professions. He is the mediator of the recommendations and messages compiled in the guideline: These include, among other things, the reduction of sugary drinks and the observance of portion sizes, the alignment of the food offer in daycare centers and all-day schools to the quality standards of the German Society for Nutrition and the promotion of physical activity in the Childhood and Adolescence.

\r\n\r\n

Therefore, according to the guideline, the prevention of obesity should be given an essential priority in the training and further education of doctors.

\r\n","createDate":"2020-08-30T09:48:00","status":1,"picture":"https://cdn.clinicways.com/news/a66c9477-e5f1-44c5-8f23-fd0f018e00df/Main.JPEG","guid":"a66c9477-e5f1-44c5-8f23-fd0f018e00df","newsType":1,"seoUrl":"health-insurance-companies-too-hesitant","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"The reason: Outpatient offers are still only hesitantly supported by health insurance companies","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":180,"title":"Preventing obesity in children requires healthy living conditions","newsContent":"

Berlin - Behavioral preventive approaches are not enough to do something against obesity in children and adolescents under today's obese living conditions. Successful obesity prevention primarily requires measures to prevent the situation, which must be initiated by society and politics. This is shown by the scientific studies on which the guideline “Therapy and Prevention of Obesity in Children and Adolescents” presented today is based.

\r\n\r\n

The evidence-based S3 guideline was developed by 40 experts from 16 medical-scientific societies, professional associations and other organizations. Leading the way were the Working Group on Obesity in Child and Adolescent Ages (AGA) of the German Obesity Society (DAG) and the German Society for Child and Adolescent Medicine (DGKJ).

\r\n\r\n

The guidance and training of affected children and their families with the aim of changing their personal lifestyle in multimodal obesity therapy can also be promising under certain circumstances. This applies in particular to the education of children of primary school age and especially their families. Nevertheless, the almost 80-page guideline states that the “therapeutic effects achieved are rather low” and “often do not meet the expectations of those affected”.

\r\n\r\n

According to experts, children and young people are most likely to benefit from outpatient services. “That is why the recommendation 'outpatient before inpatient' clearly applies to obesity therapy,” said Susanna Wiegand, former spokeswoman for the AGA and since October Vice President of the German Obesity Society. However, there are too few places for these concepts, according to which the child is cared for in the midst of family, school and friends.

\r\n","createDate":"2020-08-29T12:47:00","status":1,"picture":"https://cdn.clinicways.com/news/b81dea01-9bb3-4443-957e-c7c1e53da646/Main.JPEG","guid":"b81dea01-9bb3-4443-957e-c7c1e53da646","newsType":1,"seoUrl":"preventing-obesity-in-children-requires-healthy-living-conditions","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Berlin - Behavioral preventive approaches are not enough to do something against obesity in children and adolescents under today's obese living conditions.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":177,"title":"More overweight adults","newsContent":"

Berlin - The number of adults who are very overweight continues to increase. While the numbers of children and adolescents have now stagnated, adults are still seeing an increase in those affected by obesity, according to the Federal Government's response to a small question from the FDP parliamentary group.
\r\nAccording to the microcensus, a total of 16.3 percent of adults in 2017 were obese, including 14.6 percent women and 18.1 percent men. The number of those affected increases with age.
\r\nObesity is a risk factor for cardiovascular diseases and type 2 diabetes mellitus. Adults are obese if their body mass index (BMI) is 30 kg / m2 and more.
\r\nThe BMI is calculated from your height and weight. In surveys, body weight is often underestimated, but size is overestimated.

\r\n","createDate":"2020-08-28T08:45:00","status":1,"picture":"https://cdn.clinicways.com/news/1b47ab61-ce8d-4517-ac1d-417991b985bc/Main.JPEG","guid":"1b47ab61-ce8d-4517-ac1d-417991b985bc","newsType":1,"seoUrl":"more-overweight-adults","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Berlin - The number of adults who are very overweight continues to increase. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":174,"title":"Obesity: Students who eat in the canteen are less affected","newsContent":"

Leipzig - Children who eat in the canteen at school and who shop less often in kiosks and grocery stores near the school due to a lack of pocket money tend to be obese less often. This is what scientists from the Integrated Research and Treatment Center (IFB) Obesity Diseases of the Leipzig University Medical Center report.

\r\n\r\n

To this end, the researchers examined 1,215 children at 41 Leipzig schools. Students in grades four, six, seven and eight participated in elementary and secondary schools. "Recognizing changeable influences is important in order to create a health-promoting environment in schools for all children," said Tobias Lipek, head of the Leipzig School Nutrition Study, explaining the background to the study.

\r\n\r\n

The evaluation of the study showed that around twelve percent of children are overweight or obese. According to the IFB, this value corresponds to the findings of other Germany-wide studies. 67 percent of the students go to the school canteen regularly.

\r\n\r\n

“The absolute figures show that among the students who eat regularly in the school canteen, there are fewer overweight children than among those who do not participate,” said Peggy Ober, researcher and coordinator of the project. However, this is only a trend.

\r\n\r\n

With regard to the menu, the researchers found that six out of ten providers meet at least 60 percent of the quality criteria of the German Nutrition Society. Around nine percent of children usually do not eat breakfast on school days, and almost six percent never eat it.

\r\n\r\n

“We have seen that the proportion of overweight students was higher among those who did not have breakfast. However, our cross-sectional study cannot make any statements about what is cause and what is consequence. We can only show the context, ”said Ober.

\r\n\r\n

According to the results of the study, the Leipzig students have an average of 15.37 euros in pocket money per month. "Our figures show that the students who have a lot of pocket money at their disposal go to the local shops and buy groceries more often," said Lipek.

\r\n\r\n

Since children tended to buy unhealthy goods in supermarkets and fast food shops, the researchers conclude that better acceptance and higher attendance at school lunches could contribute to improved child health.

\r\n\r\n

The researchers recommend setting up an intervention study on the basis of the available data: It is conceivable, for example, to examine the influence of a breakfast offer for all children in school on overweight and obesity or to test various measures to improve the quality and acceptance of school meals.

\r\n","createDate":"2020-08-27T06:45:00","status":1,"picture":"https://cdn.clinicways.com/news/09ddaf4d-d08c-495b-bd5b-a4ac938f30f0/Main.JPEG","guid":"09ddaf4d-d08c-495b-bd5b-a4ac938f30f0","newsType":1,"seoUrl":"obesity-students-who-eat-in-the-canteen-are-less-affected","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Leipzig - Children who eat in the canteen at school and who shop less often in kiosks and grocery stores near the school due to a lack of pocket money tend to be obese less often","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":171,"title":"Cancer researchers for more political engagement against child obesity","newsContent":"

Heidelberg - being overweight is a major cancer risk. Epidemiologists from the German Cancer Research Center (DKFZ) in Heidelberg have pointed this out. "Above all, the increasing obesity in early childhood urgently requires preventive measures", the scientists declared on the occasion of today's "World Obesity Day".

\r\n\r\n

According to the DKFZ researchers, around 30,000 people in Germany develop cancer every year because of their overweight. In particular, postmenopausal breast cancer, colon and rectal cancer, uterine cancer, esophageal cancer and renal cell cancer are significantly more common in obese people than in people of normal weight.

\r\n\r\n

In addition, obese people are more likely to develop liver or pancreatic cancer, ovarian cancer or multiple myeloma, they explained. The study data also indicated a relationship between dose and effect: the more pronounced the obesity, the higher the risk of cancer.

\r\n\r\n

The obesity risk factor often has its origins in early childhood: “It is to be expected that by 2022 there will be more obese than underweight 5 to 19 year olds worldwide. Within just 40 years, between 1975 and 2016, the rate of obese children rose from less than one percent to almost six percent for girls and almost eight percent for boys, ”explains DKFZ epidemiologist Hermann Brenner.

\r\n\r\n

He therefore sees a considerable need for political action: "Preventive measures should be given top priority," he emphasized. Simple labeling of food and a health-promoting price policy, for example through staggered VAT rates, could provide important incentives for a healthy diet in the family. The school environment should also urgently promote a balanced diet and sufficient exercise

\r\n","createDate":"2020-08-26T10:41:00","status":1,"picture":"https://cdn.clinicways.com/news/4807c8b0-ec14-42e5-9d88-f1fd4832ee7e/Main.JPEG","guid":"4807c8b0-ec14-42e5-9d88-f1fd4832ee7e","newsType":1,"seoUrl":"cancer-researchers-for-more-political-engagement-against-child-obesity","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Heidelberg - being overweight is a major cancer risk. Epidemiologists from the German Cancer Research Center (DKFZ) in Heidelberg have pointed this out. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":168,"title":"COVID-19: Obesity increases risk of hospitalization","newsContent":"

New York - In addition to cardiovascular disorders and diabetes, obesity is one of the risk factors for a severe course of COVID-19 disease. This emerges from a case series in medRxiv (2020; doi: 10.1101 / 2020.04.08.20057794).

\r\n\r\n

More than 1/3 of all Americans are obese with a body mass index of more than 30 kg / m2. Obesity increases susceptibility to a number of diseases, and severe courses of COVID-19 appear to be no exception.

\r\n\r\n

Of the 4,103 patients treated at any of the 4 clinics and 260 outpatient centers at NYU Langone Medical Center, 1,101 were obese. The share of 26.8% is thus below the national average, which could be related to the fact that the facility affiliated with the University of New York (NYU) treats better-off residents of the metropolis.

\r\n\r\n

About half of the patients diagnosed with COVID-19 had to be hospitalized. These persons were older (on average 62 versus 41 years), more often male (62.6 versus 39.0%), they had more frequent chronic previous illnesses (71.9 versus 29.9%) and they were more often obese (39.8 versus 14.4%) than patients with COVID-19 who were not admitted to the hospital.

\r\n\r\n

In a regression analysis by researchers at NYU's Grossman School of Medicine, obesity was one of the top risk factors for hospitalization by age. Leora Horwitz's team determined an odds ratio of 66.8 for an age over 75 years. The 65- to 74-year-olds also had a significantly higher risk of hospitalization with an odds ratio of 10.9. A BMI of over 40 kg / m2 (odds ratio 6.2) and a BMI of 30 to 40 kg / m2 (odds ratio 4.3) followed in the sequence.

\r\n\r\n

Obesity was about as much a risk to patients as heart failure (odds ratio 4.3), but significantly more than lung diseases (odds ratio 1.3) or cancer (odds ratio 1.2). It was striking that, in addition to diabetes mellitus (odds ratio 2.8), chronic kidney disease (odds ratio 3.1) favored a severe course.

\r\n\r\n

\r\nObesity also increased the risk of a life-threatening course of COVID-19 that required intensive medical treatment (with or without ventilation) or hospice care and / or death. The odds ratio was 1.38 for a BMI of 30 to 40 kg / m2 and 1.73 for a BMI over 40 kg / m2.

\r\n\r\n

It is unclear why more severe COVID-19 courses occur in obese patients. Horwitz suspects that the inflammatory reactions associated with (visceral) obesity play a role.

\r\n\r\n

The predictors of a life-threatening course included - regardless of obesity - a low blood oxygen saturation of less than 88% (odds ratio 6.99) and a D-dimer of over 2500 ng / ml (odds ratio 6.9) Ferritin above 2,500 ng / ml (odds ratio 6.9) and a C-reactive protein above 200 mg / l (odds ratio 5.8) on admission.

\r\n","createDate":"2020-08-25T11:39:00","status":1,"picture":"https://cdn.clinicways.com/news/e7204f4d-2996-4de9-855f-6c7f40b718e0/Main.JPEG","guid":"e7204f4d-2996-4de9-855f-6c7f40b718e0","newsType":1,"seoUrl":"covid-19-obesity-increases-risk-of-hospitalization","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"New York - In addition to cardiovascular disorders and diabetes, obesity is one of the risk factors for a severe course of COVID-19 disease. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":165,"title":"SARS-CoV-2: UK agency views obesity as a COVID-19 risk","newsContent":"

London - Obesity is possibly one of the most important risk factors for a severe course of infection with the new coronavirus SARS-CoV-2. While the British Prime Minister attributes his serious illness to his weight problems and the government has launched a major campaign against obesity, the health authority Public Health England is summarizing the current state of knowledge in a report.

\r\n\r\n

Great Britain has one of the highest rates of overweight and obese adults in Europe: 67% of men and 60% of women are overweight with a body mass index (BMI) of over 25 kg / m2, and 26% and 29% are respectively even obese with a BMI of over 30 kg / m2.

\r\n\r\n

Obesity is particularly widespread among socially disadvantaged sections of the population and in the BAME group ("Black, Asian, and minority ethnic"). Above all, the women among the “blacks” fall out of the ordinary: 53.6% of them are obese, while the proportion of men at 27.7% is no higher than that of the “whites”. Asians are less obese than the average, with 16.3% of men and 23.6% of women.

\r\n\r\n

Whether the high prevalence of weight problems in the population (and especially in the BAME group) is responsible for the fact that the COVID-19 epidemic was more violent in the UK than in other countries has not been established, according to Public Health England. However, the report provides a number of clear indications that show that people with weight problems are at greater risk of developing COVID-19 particularly hard when infected with SARS-CoV-2.

\r\n\r\n

This includes, for example, that 7.9% of critically ill patients in the UK intensive care units had a BMI of over 40, compared with 2.9% in the general population. The risk of intensive care increased exponentially with the BMI.

\r\n\r\n

The hazard ratios were 1.64 for overweight people (BMI 25 to 29.9 kg / m2), 2.59 for people with normal obesity (BMI 30 to 34.9 kg / m2) and for people with marked obesity (BMI 35 and higher) 4.35. Obese people had a 33% increased risk of not surviving the disease in a study at 208 UK clinics.

\r\n\r\n

Many obese people have other health problems, especially type 2 diabetes, which is also a risk factor for a severe course of COVID-19. According to the report, this only explains part of the disease risk.

\r\n\r\n

According to the report, possible mechanisms for a direct impact of obesity are impaired breathing due to fat deposits in the upper airways and on the thorax, the inflammatory reactions in the body associated with obesity and possibly also an increased immune reaction to the pathogen that leads to the development of thrombosis favored.

\r\n\r\n

The report points to numerous studies in which a weight loss of 5 to 10 kg has reduced the risk of disease and death in obese people. It is unclear whether weight loss would also protect against COVID-19, but in view of the experience with other diseases, it can be assumed

\r\n","createDate":"2020-08-24T09:39:00","status":1,"picture":"https://cdn.clinicways.com/news/48e9ae3c-731e-478b-9110-dbacf82b6021/Main.JPEG","guid":"48e9ae3c-731e-478b-9110-dbacf82b6021","newsType":1,"seoUrl":"sars-cov-2-uk-agency-views-obesity-as-a-covid-19-risk","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"London - Obesity is possibly one of the most important risk factors for a severe course of infection with the new coronavirus SARS-CoV-2.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":162,"title":"COVID-19: Morbid obesity increases the risk of death in \"younger\" men","newsContent":"

Pasadena / California - Morbid obesity with a body mass index (BMI) of over 40 kg / m2 increases the risk of dying of COVID-19 after an infection with SARS-CoV-2, even in otherwise physically healthy younger men. This is shown by the analysis of a California health insurer in the Annals of Internal Medicine (2020; DOI: 10.7326 / M20-3742).

\r\n\r\n

\r\nThe US is one of the countries with the highest percentage of obese people in its population. According to official statistics, 42% of adults have a BMI of over 30 kg / m2, which marks the limit of obesity.

\r\n\r\n

\r\nAmong the 6,916 COVID-19 patients at Kaiser Permanente Southern California, the region's largest health insurer, one in two was obese. Almost every tenth person with a BMI of 40 kg / m2 or higher even had morbid obesity, which is classified as an acute health risk.
\r\nIn morbid obesity, the masses of fat on the chest lead to an impairment of breathing, which among other things favors the development of pneumonia. In addition, there is usually a fatty degeneration of the internal organs, including the heart muscle, which further reduces the immune system in the event of illness.

\r\n\r\n

\r\nThe fatty tissue in the abdominal area is also biologically active. There is an increased release of hormones, which are held responsible for the health disorders that occur more frequently in obese people than in other people.

\r\n\r\n

\r\nThose insured with COVID-19 from Kaiser-Permanente suffered more often from comorbidities such as high blood pressure (24%), hyperlipidemia (23%), diabetes (20%) and asthma (18%), which (apart from asthma) unite favor a severe course of COVID-19.
\r\nHowever, these comorbidities do not explain the increased risk of death in extremely obese patients, which Sara Tartof and employees of Kaiser Permanente in Pasadena have determined.
\r\nEven after considering other risk factors, insured persons with a BMI of 40 to 44 kg / m2 had an almost 3-fold higher risk of dying from COVID-19 than members of normal weight (risk ratio 2.68; 95% confidence interval: 1, 43 to 5.04). With a BMI of 45 kg / m2 or more, the risk ratio increased to 4.18 (2.12 to 8.26).
\r\nMorbid obesity was the most important risk factor, along with older people (risk ratio up to 43.21 in the over 80-year-old group) and an organ transplant (risk ratio 6.54).
\r\nInterestingly, the increased risk of death from COVID-19 due to morbid obesity was limited to “younger” men. In the age group under 60 years, a BMI of 40 to 44 kg / m2 was associated with a risk ratio of 17.14 (3.37 to 87.27). With a BMI of over 45, the risk ratio was 12.35 (2.28 to 66.77).
\r\nFor the entire group of men, Tartof determined a risk ratio of 4.81 (2.15 to 10.78) for a BMI of 40 to 44 kg / m2 and of 10.04 (4.01 to 25.09) for a BMI of 45 kg / m2 or more.
\r\nThe wide 95% confidence intervals show that the analysis has reached its limits. It remains unclear why women and older men do not have an increased risk of death regardless of other risk factors.

\r\n","createDate":"2020-08-23T10:39:00","status":1,"picture":"https://cdn.clinicways.com/news/49c70721-394d-4ae1-b9a1-1ec9c05ecaaf/Main.JPEG","guid":"49c70721-394d-4ae1-b9a1-1ec9c05ecaaf","newsType":1,"seoUrl":"covid-19-morbid-obesity-increases-the-risk-of-death-in-younger-men","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Pasadena / California - Morbid obesity with a body mass index (BMI) of over 40 kg / m2 increases the risk of dying of COVID-19 after an infection with SARS-CoV-2, even in otherwise physically healthy younger men. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":159,"title":"Corona transmission: how dangerous are public toilets?","newsContent":"

Yangzhou / Seattle - When it comes to high-risk locations for corona infection, public toilets could play a role. This is suggested by at least one study by Chinese scientists, the results of which were published in the journal Physics of Fluids (Physics of Fluids, 2020; DOI: 10.1063 / 5.0013318).

\r\n\r\n

The researchers examined how small suspended particles are distributed in the air when flushing a toilet. It is possible that virus-contaminated aerosol clouds could be inhaled by other people, they conclude. Studies previously had shown that the stool of infected people may contain coronavirus material.

\r\n\r\n

The physicists at the University of Yangzhou used detailed computer models to trace the water and air currents that arise when flushing with different types of toilets. Accordingly, vortices are generated in the toilet, which continue in the form of aerosol clouds above the bowl - to a height of just under a meter, where they can be inhaled or deposited on surfaces.

\r\n\r\n

Aerosols are a mixture of solid or liquid suspended particles in the air. The small micrometer-sized droplets can hover in the air for more than a minute, as the researchers explain. With toilet types with 2 water influences, the aerosols flew up even faster.

\r\n\r\n

"It can be assumed that this speed will be even higher if a toilet is used frequently, for example in a family toilet or a public toilet in a densely populated room," explains co-author Ji-Xiang Wang. The solution, however, is simple: close the toilet lid before flushing. However, many toilets in public spaces, especially in the United States, would not have a lid - a fact that Clemens Wendtner from Munich Clinic Schwabing also points out in an independent comment.

\r\n\r\n

In this context, the infectiologist recalls discussions about the spread of the virus on cruise ships. "I don't think such spreading is out of the question." In addition, there are more and more studies on viral load in the stool of COVID-19 patients.

\r\n\r\n

Wendtner himself, together with the virologist Christian Drosten from the Berlin Charité, published an analysis in the journal Nature, in which the course of the infection of 9 German patients was reconstructed. It was shown that SARS-CoV-2 probably also increased in the gastrointestinal tract. However, no infectious viruses could be documented in the patient's stool.

\r\n\r\n

"However, this is always difficult with stool samples because E. coli bacteria always overgrow everything else," notes Wendtner. "However, we were unable to detect any replication-capable viruses." Nevertheless, it cannot be completely ruled out that fecal excretions also pose a risk of infection going out.

\r\n\r\n

At least that's the warning from researchers at the U.S. Swedish Medical Center, who analyzed 29 studies on gastrointestinal consequences of COVID-19 disease in a meta-analysis involving 4,805 patients.

\r\n\r\n

As they report in the journal JAMA Network Open, diarrhea, nausea or vomiting were symptoms of more than ten percent of all infected, regardless of which the virus was found in the stool in 40 percent of those infected.

\r\n","createDate":"2020-08-22T08:39:00","status":1,"picture":"https://cdn.clinicways.com/news/ffe64c02-91a3-4362-b973-ba81a23f136e/Main.JPEG","guid":"ffe64c02-91a3-4362-b973-ba81a23f136e","newsType":1,"seoUrl":"corona-transmission-how-dangerous-are-public-toilets","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Yangzhou / Seattle - When it comes to high-risk locations for corona infection, public toilets could play a role. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":156,"title":"COVID-19: Lung cancer patients are (rarely) treated in intensive care","newsContent":"

Milan - Lung cancer patients may be at a disadvantage compared to other patients with COVID-19. The results of a patient registry in Lancet Oncology (2020; DOI: 10.1016 / S1470-2045 (20) 30314-4) show that only every tenth person who met the criteria for intensive care was also treated in an intensive care unit. Lung cancer patients have chances of surviving the disease, even if the death rate is high.

\r\n\r\n

The survival times of lung cancer patients have improved in recent years thanks to new treatments (tyrosine kinase inhibitors, immunotherapy). As a result, lung cancer patients are treated more often in the clinics during the current COVID-19 pandemic. However, many doctors rate the prognosis of these patients as so poor that they do not consider treatment in an intensive care unit.

\r\n\r\n

The "Thoracic Cancers International COVID-19 Collaboration" (TERAVOLT) has therefore set up an international patient registry, in which 42 centers in 8 countries participate. By April 12, data had been collected on 200 patients that Marina Garassino of the Istituto Nazionale dei Tumori in Milan and co-workers have now evaluated.

\r\n\r\n

Most patients (76%) suffered from non-small cell lung cancer (NSCLC), the most common type of lung cancer for which tobacco smoking is the primary risk factor. The other patients had small cell bronchial carcinoma (15%) or some rare types of tumor in the thoracic area (thymoma, carcinoid or mesothelioma). Most patients received their first-line therapy at the time of their COVID-19 disease, which can now significantly extend their survival time.

\r\n\r\n

According to Garassino, 134 (88%) of the 152 patients treated in a hospital met the criteria for referral to an intensive care unit. However, only 13 patients (10%) were actually treated there, 9 of whom were mechanically ventilated. The reasons were usually not communicated by the doctors. However, only 6 patients had refused intensive care.

\r\n\r\n

Garassino suspects that the limited capacity at the height of the epidemic - most of the patients were from Italy, France and Spain - led to lung cancer patients in a triage being excluded from intensive care because the doctors believed that the patients would hardly have any chance of survival anyway.

\r\n","createDate":"2020-08-21T09:39:00","status":1,"picture":"https://cdn.clinicways.com/news/d9a4b8d1-909a-4474-a206-fac8e4f46993/Main.JPEG","guid":"d9a4b8d1-909a-4474-a206-fac8e4f46993","newsType":1,"seoUrl":"covid-19-lung-cancer-patients-are-rarely-treated-in-intensive-care","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Milan - Lung cancer patients may be at a disadvantage compared to other patients with COVID-19.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.aerzteblatt.de/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":153,"title":"ALK gene and its effects on weight loss: could a weakening gene be found?","newsContent":"

Why do some people stay thin effortlessly when other people are dieting to stay fit or doing heavy sports in gyms?

\r\n\r\n

The study team led by Josef Penninger, director of the Institute of Life Sciences at the University of British Columbia and professor at the Department of Medical Genetics at the same university, examined the data of 47,122 people between the ages of 20 and 44 in the Estonian biobank (the bank where the genetic and biological material is kept for research). Clinical data and DNA
\r\nSamples from healthy and frail individuals were then compared to those from normal weight individuals. As a result of the study, the scientists discovered a change only in the ALK gene in weak individuals.

\r\n\r\n

Scientists have known that the ALK gene mutates in many cancers and is therefore known as the oncogene gene that causes tumor formation. The effects of ALK genes other than cancer were not clear. With this new invention, however, it was claimed that the ALK gene formed as a new weak gene resistance to weight gain.
\r\nResearchers also found that mice and flies with ALK genes have been shown to remain weak and resistant to a diet that promotes obesity. In this study, a mouse with ALK genes was found to be less overweight and less body fat than a normal mouse, although eating the same foods and with the same level of exercise. This study also showed that the ALK gene plays a role in body fat formation and burns more fat.

\r\n\r\n

Could This Gene Be The Solution To Obesity?
\r\nResearchers believe that new therapies that focus on the ALK gene could help scientists in their fight against obesity in the future. The name at the start of the study spoke as follows :;

\r\n\r\n

\r\n
We know the people who are metabolically healthy and do not gain weight, although they make up about 1 percent of society and we all eat what we want; You eat a lot and you don't exercise, but you don't gain weight. Everyone studies the genetics of obesity and obesity.
\r\nSo we thought we could turn it around and started working on the weakness. If you think about it, it's a realistic thought to see if we can stay weak by turning off the ALK gene and reducing the function of this gene. ALK gene inhibitors are already used to treat cancer. We can use ALK inhibitors in the future and we will really try to use them.
\r\n

\r\n\r\n

\r\nFurther studies are needed to use ALK inhibitors for this purpose. The team is planning further studies to find out how ALK-bearing neurons affect the brain at the molecular level.

\r\n","createDate":"2020-05-27T10:27:00","status":1,"picture":"https://cdn.clinicways.com/news/bc4358a8-0243-4d63-af2e-13af664875bf/Main.JPEG","guid":"bc4358a8-0243-4d63-af2e-13af664875bf","newsType":1,"seoUrl":"alk-gene-and-its-effects-on-weight-loss-could-a-weakening-gene-be-found","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Why do some people stay thin effortlessly when other people are dieting to stay fit or doing heavy sports in gyms?","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://evrimagaci.org/alk-geni-ve-zayiflama-uzerindeki-etkisi-zayiflik-geni-bulunmus-olabilir-mi-8775","categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":150,"title":"Where do we stand on women’s health in 2020? ","newsContent":"

This year marks 25 years since countries committed to intensify their efforts towards women’s empowerment and gender equality through the Beijing Platform for Action. Today, we mark International Women’s Day 2020 and focus attention on the impact of gender equality on women’s health in the WHO European Region throughout their lives.

\r\n\r\n

Europe has some of the highest levels of gender equality in the world, but progress has been slow and many differences between countries remain. According to existing gender equality indexes, no Member State has achieved full equality. Gender inequalities impact women’s health in many ways.

\r\n\r\n

European governments set priorities for gender equality

\r\n\r\n

European countries have outlined actions and future priorities for gender equality as part of the Beijing+25 review. Close to all European Member States have submitted national review reports. An assessment of the priorities outlined in these reports in the context of the 2030 Agenda for Sustainable Development shows the following.

\r\n\r\n

\r\n\t
Eliminating violence against women and girls, and implementing measures that recognize, value and redistribute women’s unpaid care work, remain top priorities across Europe – they are Sustainable Development Goal (SDG) targets and vital for women’s health in Europe.
\r\n\t

\r\n\r\n

\r\n\t
Ensuring women’s sexual and reproductive health and rights is at the core of gender equality and is also an SDG target, but is less frequently prioritized by countries now compared to previous years.
\r\n\t
\r\n\t
Addressing harmful gender norms and stereotypes, as well as increasing the digital inclusion of women – both crucial for women’s health and well-being – are upcoming or new priorities that countries will put more focus on in the future.
\r\n\t

\r\n\r\n

In September 2020, European Member States will review achievements in gender equality and their impacts on both women’s and men’s health as part of monitoring progress under the Strategy on Women’s Health and Well-being in the WHO European Region (2016) and the Strategy on the Health and Well-being of Men in the WHO European Region (2018).

\r\n\r\n

Lower life satisfaction among girls

\r\n\r\n

Gender stereotypes begin to impact health and well-being early in life. Health Behaviour in School-aged Children survey data show that among European adolescents aged 15 years, 43% of girls were unsatisfied with their bodies compared to 22% of boys. Among the girls, 26% reported being on a diet, even though only 13% were overweight (compared to 11% of boys being on a diet and 22% being overweight).

\r\n\r\n

The same data shows a gender gap in life satisfaction among adolescents, with girls more likely than boys to fall behind in all countries.

\r\n\r\n

High rates of violence against women

\r\n\r\n

One in 4 women in the European Region will experience physical and/or sexual intimate partner violence after the age of 15. United Nations data indicate that more than 3 quarters of victims of human trafficking are women, and that a vast majority of these women are trafficked for sexual exploitation.

\r\n\r\n

Gender inequalities for women in the workforce

\r\n\r\n

Women make up the majority of the health workforce in the European Region, yet gender inequalities within the health system persist. Female health workers still face significant barriers in terms of achieving leadership positions and income equality and in overcoming stereotypes about the health-care roles that women generally fill.

\r\n\r\n

Although numbers change from year to year, as of March 2020 only 19% of health ministers in European Member States are women; this is down from 34% in August 2019. Yet women make up 90% of the formal long-term health- and social-care workforce in countries of the Organisation for Economic Co-operation and Development.

\r\n\r\n

Health-care services depend heavily on women who contribute as informal caregivers, particularly for children and older people. European Union data show that gender inequalities in unpaid care provision are persistent and growing.

\r\n\r\n

Many years lived in ill health

\r\n\r\n

Women in the Region have some of the world’s highest life expectancies, but the last years of life are often characterized by ill health or disability and, usually, low levels of social protection. This is partially due to unequal gender participation in the labour market and the gender imbalance in providing care.

\r\n\r\n

Women in Europe live an average of 10 years in ill health, while for men the figure is 6 years. With an ageing European population, and with 70% of the 14 million people currently over the age of 85 being women, this group can only be expected to grow

\r\n","createDate":"2020-03-10T23:00:00","status":1,"picture":"https://cdn.clinicways.com/news/e7c7f688-6c0d-4de6-af71-6f39f2e3452d/Main.JPEG","guid":"e7c7f688-6c0d-4de6-af71-6f39f2e3452d","newsType":1,"seoUrl":"where-do-we-stand-on-women-s-health-in-2020","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"This year marks 25 years since countries committed to intensify their efforts towards women’s empowerment and gender equality through the Beijing Platform for Action","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"http://www.euro.who.int/de ","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":147,"title":"Bad breath: What causes it and what to do about it","newsContent":"

Almost everyone experiences bad breath once in a while. But for some people, bad breath is a daily problem, and they struggle to find a solution. Approximately 30% of the population complains of some sort of bad breath. Halitosis (Latin for “bad breath”) often occurs after a garlicky meal or in the morning after waking. Other causes of temporary halitosis include some beverages (including alcoholic drinks or coffee) and tobacco smoking.

\r\n\r\n

Some people may not be aware of their own halitosis and learn about it from a relative, friend, or coworker, causing some degree of discomfort and distress. In severe cases, bad breath may negatively impact personal relationships and a person’s quality of life.

\r\n\r\n

What causes bad breath? And what can you do about it?

\r\n\r\n

Bad breath can originate both inside and outside of the mouth. Bad breath is typically caused by bacteria present on the teeth and debris on the tongue. So it’s no surprise that most cases of halitosis are associated with poor oral hygiene, gum diseases such as gingivitis and periodontitis, and dry mouth, a condition in which the salivary glands cannot make enough saliva to keep your mouth moist. A visit with a dentist may help rule out periodontal disease and identify any mouth problem that could be contributing to bad breath.

\r\n\r\n

Tonsillitis, respiratory infections such as sinusitis or bronchitis, and some gastrointestinal diseases may be responsible for a small number of cases of bad breath. Advanced liver or kidney disease and uncontrolled diabetes can also lead to unpleasant breath. In these cases, a person is likely to experience significant symptoms beyond bad breath, and should seek medical attention.

\r\n\r\n

Sometimes people think they have bad breath, even when their breath is objectively fine. This is called “pseudo-halitosis.” Halitophobia, or fear of bad breath, is real and may persist despite reassurance from a doctor. People with pseudo-halitosis respond well to reassurance, and may benefit from speaking with a therapist or psychiatrist who has expertise in the field.

\r\n\r\n

A person complaining of bad breath can be initially evaluated by a primary care physician (PCP). The doctor will begin with a thorough medical and dental history and an oral exam. Tests may be done to confirm the presence of halitosis by measuring the strength of bad breath on a predefined scale, and by using instruments to detect specific compounds related to halitosis. The intensity of malodor is usually assessed by the doctor smelling the air that the person breathes out through the nose or mouth, or from judging the odor of a tongue scraping, a length of dental floss, or a dental appliance such as a night guard.

\r\n\r\n

Your PCP may refer you to a dentist if there is evidence of dental or gum problems, which is the cause in the majority of people with bad breath. Visits with other medical specialists are warranted when an underlying medical problem requires attention.

\r\n\r\n

Tips to improve bad breath

\r\n\r\n

Here are some helpful tips to improve bad breath:

\r\n\r\n

Brush your teeth at least twice a day, after meals, with a fluoridated toothpaste.
Avoid tobacco smoking and chewing tobacco-based products.
Rinse and gargle with an alcohol-free mouthwash before bed.
If you have dry mouth, make sure to drink enough fluids throughout the day and use over-the-counter moisturizing agents, such as a dry mouth spray, rinses, or dry mouth moisturizing gel. If you don’t see any improvement, you may want to schedule a visit with an oral medicine specialist. Oral medicine doctors provide comprehensive care for mucosal diseases, salivary gland disorders, orofacial pain conditions, and oral complications of cancer therapies, among other things.
Visit your dentist regularly. Remember, oral causes are responsible for most cases of bad breath!

\r\n","createDate":"2020-03-10T22:55:00","status":1,"picture":"https://cdn.clinicways.com/news/4cf5bfca-827c-498b-98e5-ff489bb61aa8/Main.JPEG","guid":"4cf5bfca-827c-498b-98e5-ff489bb61aa8","newsType":1,"seoUrl":"bad-breath-what-causes-it-and-what-to-do-about-it","author":null,"categoryid":10,"mainCategoryid":0,"categoryName":"Diş ve Ağız Sağlığı","shortDescription":"Almost everyone experiences bad breath once in a while. But for some people, bad breath is a daily problem, and they struggle to find a solution. Approximately 30% of the population complains of some sort of bad breath. Halitosis (Latin for “bad breath”) often occurs after a garlicky meal or in the morning after waking. Other causes of temporary halitosis include some beverages (including alcoholic drinks or coffee) and tobacco smoking. Some people may not be aware of their own halitosis and learn about it from a relative, friend, or coworker, causing some degree of discomfort and distress. In severe cases, bad breath may negatively impact personal relationships and a person’s quality of life. What causes bad breath? And what can you do about it? Bad breath can originate both inside and outside of the mouth. Bad breath is typically caused by bacteria present on the teeth and debris on the tongue. So it’s no surprise that most cases of halitosis are associated with poor oral hygiene, gum diseases such as gingivitis and periodontitis, and dry mouth, a condition in which the salivary glands cannot make enough saliva to keep your mouth moist. A visit with a dentist may help rule out periodontal disease and identify any mouth problem that could be contributing to bad breath. Tonsillitis, respiratory infections such as sinusitis or bronchitis, and some gastrointestinal diseases may be responsible for a small number of cases of bad breath. Advanced liver or kidney disease and uncontrolled diabetes can also lead to unpleasant breath. In these cases, a person is likely to experience significant symptoms beyond bad breath, and should seek medical attention. Sometimes people think they have bad breath, even when their breath is objectively fine. This is called “pseudo-halitosis.” Halitophobia, or fear of bad breath, is real and may persist despite reassurance from a doctor. People with pseudo-halitosis respond well to reassurance, and may benefit from speaking with a therapist or psychiatrist who has expertise in the field. A person complaining of bad breath can be initially evaluated by a primary care physician (PCP). The doctor will begin with a thorough medical and dental history and an oral exam. Tests may be done to confirm the presence of halitosis by measuring the strength of bad breath on a predefined scale, and by using instruments to detect specific compounds related to halitosis. The intensity of malodor is usually assessed by the doctor smelling the air that the person breathes out through the nose or mouth, or from judging the odor of a tongue scraping, a length of dental floss, or a dental appliance such as a night guard. Your PCP may refer you to a dentist if there is evidence of dental or gum problems, which is the cause in the majority of people with bad breath. Visits with other medical specialists are warranted when an underlying medical problem requires attention. Tips to improve bad breath Here are some helpful tips to improve bad breath: Brush your teeth at least twice a day, after meals, with a fluoridated toothpaste. Avoid tobacco smoking and chewing tobacco-based products. Rinse and gargle with an alcohol-free mouthwash before bed. If you have dry mouth, make sure to drink enough fluids throughout the day and use over-the-counter moisturizing agents, such as a dry mouth spray, rinses, or dry mouth moisturizing gel. If you don’t see any improvement, you may want to schedule a visit with an oral medicine specialist. Oral medicine doctors provide comprehensive care for mucosal diseases, salivary gland disorders, orofacial pain conditions, and oral complications of cancer therapies, among other things. Visit your dentist regularly. Remember, oral causes are responsible for most cases of bad breath!","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.health.harvard.edu/blog/bad-breath-what-causes-it-and-what-to-do-about-it-2019012115803","categoryicon":"category-icon-dentist","categorycolor":"076088","language":"En","newsList":[],"doctors":[]},{"newsid":144,"title":"Women's Health - why the \"little difference\" has a big impact ","newsContent":"

Women and men do not only suffer from other diseases, they are also differently ill. They describe pain differently, classify it differently and deal with diseases differently.

\r\n\r\n

The realization that "women are different - men too" took a long time to gain attention in medical research beyond reproductive medicine. Only since 2001 has there been a term for gender-related medicine: Gender Medicine - shaped by the World Health Organization.

\r\n\r\n

Gender Medicine: The science of the "little difference"

\r\n\r\n

Men and women perceive health and illness differently - and also speak about them differently. While it is usually embarrassing for men to show pain, women report their pain, fears and irritations more often. According to a Forsa survey commissioned by TK, eight out of ten women talk to friends, partners and family about serious concerns. And that's good. Because the exchange with friends and family relieves and thus contributes to well-being.

\r\n\r\n

How do women deal with their health?

\r\n\r\n

The numbers are clear: According to the Federal Statistical Office, women have five years longer life expectancy than men. However, the subjective feeling is different: women rate their own health worse than men do. Only every sixth of the women thinks they are in good health, for men it is every fourth.

\r\n\r\n

One possible reason: women are significantly more sensitive to disease symptoms and behave more preventively. "They really want to get to the bottom of problems, instead of just getting a grip on complaints for a short time," explains Maria Schwormstedt, a doctor at TK. But that does not work with any disease - heart attack is the best example.

\r\n\r\n

Heart attack is not just for men

\r\n\r\n

Cardiovascular diseases are the leading cause of death - in both men and women. Still, there are differences: men suffer a heart attack more often than women, but women rarely survive. This could be due to the more unspecific symptoms women experience. Tight feeling in the chest, shortness of breath and radiating pain in the left arm - the classic textbook symptoms primarily apply to men. Women, on the other hand, complain more about nausea, unusual tiredness and dizziness as well as back or neck pain. Therefore, not every woman suspects a heart attack immediately, letting valuable time pass until the right treatment.

\r\n\r\n

The risk increases after the menopause

\r\n\r\n

Until the menopause, women have a kind of hormonal protection and therefore a lower risk of suffering a heart attack. The risk later equalizes between the two genders. Therefore women as well as men should be aware of the risk factors (e.g. high blood pressure, diabetes mellitus or smoking) and try to minimize them. Regular exercise, a balanced diet and last but not least nicotine reduction significantly reduce the risk of heart attacks in both genders.

\r\n\r\n

Men or women - who is more stressed?

\r\n\r\n

Just only those who spend at least ten hours a day in the office and climb the career ladder with great strides are really stressed out? Are you kidding me? According to the TK survey, housewives and working mothers are just as stressed as managers: Almost 40 percent feel themselves at the limit. "The increasing pressure in the working world, increasingly connected with the expectation to be constantly available via e-mail or mobile phone, makes it more difficult for women to reconcile family and work. The consequences are often stress-related diagnoses, "says TK doctor Schwormstedt.

\r\n\r\n

Regardless of the choice of profession, women suffer from stress more often: 35 percent of women are stressed frequently or constantly, but only 29 percent of men. Most of them are their own demands on themselves, burdened women. They want to master all tasks in family, work, social environment perfectly - and forget about their own needs.

\r\n","createDate":"2020-03-07T18:24:00","status":1,"picture":"https://cdn.clinicways.com/news/e8fedb01-092a-4452-a4c9-d4da5111a6a7/Main.JPEG","guid":"e8fedb01-092a-4452-a4c9-d4da5111a6a7","newsType":1,"seoUrl":"womens-health-why-the-little-difference-has-a-big-impact","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Women and men do not only suffer from other diseases, they are also differently ill. They describe pain differently, classify it differently and deal with diseases differently. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.tk.de/techniker/magazin/life-balance/familie/frauengesundheit-2009298","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":141,"title":"10 guidelinesof the German Nutrition Society (DGE) for a wholesome diet ","newsContent":"

A wholesome diet keeps you in good health and promotes vitality and well-being. The 10 dietary guidelines of the DGE summarise how a wholesome diet can be implemented and they are based on recent scientifc knowledge.

\r\n\r\n

1.Enjoy food diversity

\r\n\r\n

Make use of the diversity of foods and eat versatile. Choose mainly plant-based foods.

\r\n\r\n

No single food can supply all nutrients. The more varied you eat, the lower is the risk of an unbalanced diet.

\r\n\r\n

2.Vegetables and fruit – take ‘5 a day’

\r\n\r\n

Enjoy at least 3 portions of vegetables and 2 portions of fruit each day. This could also include legumes such as lentils, chickpeas and beans as well as (unsalted) nuts.

\r\n\r\n

Vegetables and fruit supply you with a plenty of nutrients, dietary fibre and phytochemicals and also contribute to satiation. Vegetables and fruits lower the risk of cardiovascular and other diseases.

\r\n\r\n

3.Favour whole-grain foods

\r\n\r\n

The whole-grain varieties of cereal products like bread, pasta, rice and flour are the best choice for your health.

\r\n\r\n

Whole-grain foods will keep you satiated longer and contain more nutrients than white flour products. Whole-grain dietary fibres reduce the risk of type 2 diabetes mellitus, dyslipidemia, colon cancer and cardiovascular diseases.

\r\n\r\n

4.Complete the choice with animal-based foods

\r\n\r\n

Consume milk and dairy products such as yoghurt and cheese daily, fish once to twice a week. If you eat meat, you should not consume more than 300 to 600 g per week.

\r\n\r\n

Milk and dairy products are a good source of high quality protein, vitamin B2and calcium. Saltwater fish supplies you with iodine, and oily fish provides important omega-3 fatty acids. Meat contains available iron as well as selenium and zinc. However, meat and particularly sausage also contain unfavourable substances.

\r\n\r\n

5.Choose health-promoting fats

\r\n\r\n

Prefer vegetable oils like rapeseed oil and margarines produced therefrom. Avoid hidden fats. Fat is often “invis-ibly“ present in processed foods like sausage, pastry, sweets, fast food and convenience products.

\r\n\r\n

Like all fats, vegetable oils provide many calories. However, they also provide essential fatty acids and vitamin E.

\r\n\r\n

6.Reduce sugar and salt intake

\r\n\r\n

Sugar-sweetened foods and beverages are not recommendable and should be avoided whenever possible. Sugar should only be consumed in small amounts.Limit the consumption of salt and reduce the proportion of high-salt foods. Be creative in flavouring with herbs and spices.

\r\n\r\n

Sugar-sweetened foods and beverages are usually low in nutrients and contain unnecessary calories. In addition, sugar increases the risk of caries. Too much salt in your food can increase your blood pressure. Salt intake should not exceed 6 g per day. Choose iodised and fluoridated salt.

\r\n\r\n

7. Water is the best choice

\r\n\r\n

Drink about 1.5 litres per day. Water or other calorie-free beverages, such as unsweetened tea, are the best choice. Sugar-sweetened and alcoholic beverages are not recommendable.

\r\n\r\n

Your body needs fluid in the form of water. Sugar-sweetened beverages provide unnecessary calories and very little important nutrients. Their consumption can promote the development of overweight and type 2 diabetes mellitus.Alcoholic beverages are also rich in calories. Furthermore, alcohol promotes the develop-ment of cancer and is also associated with other health risks.

\r\n\r\n

8.Prepare carefully cooked dishes

\r\n\r\n

Cook food as long as necessary but as short as possible, using little amount of water and fat. Avoid burning the food during roasting, grilling, baking and frying.

\r\n\r\n

A careful preparation will preserve the natural taste and conserve the nutrients. Burnt parts contain harmful substances.

\r\n\r\n

9. Mindful eating and enjoying

\r\n\r\n

Take a break while you eat and allow plenty of time for eating.

\r\n\r\n

Eating slowly and consciously promotes enjoyment and the sense of satiation.

\r\n\r\n

10.Watch your weight and stay active

\r\n\r\n

Combine a wholesome diet with plenty of physical activity. It is not only regular exercise which is helpful, but also an active daily life which includes frequent walking and cycling.

\r\n\r\n

Moderate physical activity of 30 to 60 minutes per day will promote your health and help you to control your weight.

\r\n","createDate":"2020-03-06T19:07:00","status":1,"picture":"https://cdn.clinicways.com/news/30fc5a12-b8fd-43d2-b3f2-f3726cff9333/Main.JPEG","guid":"30fc5a12-b8fd-43d2-b3f2-f3726cff9333","newsType":1,"seoUrl":"10-guidelinesof-the-german-nutrition-society-dge-for-a-wholesome-diet","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"A wholesome diet keeps you in good health and promotes vitality and well-being. The 10 dietary guidelines of the DGE summarise how a wholesome diet can be implemented and they are based on recent scientifc knowledge. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.dge.de/","categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":138,"title":"World Obesity Day","newsContent":"

Obesity and its root causes

\r\n\r\n

World obesity day encourages practical solutions to help people achieve and maintain a healthy weight, undertake proper treatment, and reverse the obesity crisis.

\r\n\r\n

Obesity rates have nearly tripled since 1975 and have increased almost five times in children and adolescents, affecting people of all ages from all social groups in both developed and developing countries. Obesity is a major risk factors for various noncommunicable diseases (NCDs), such as type 2 diabetes, cardiovascular disease, hypertension and stroke, and various forms of cancer.

\r\n\r\n

People with obesity are constantly shamed and blamed because many - including doctors, policymakers, and others - do not fully understand the root causes of obesity, which are often a complex mixture of dietary, lifestyle, genetic, psychological, sociocultural, economic and environmental factors. It is time we break the cycle of shame and blame and reevaluate our approach for addressing this complex global public health problem.

\r\n\r\n

Together we can make a difference. There is a lot we can do, including restricting the marketing to children of food and drinks high in fats, sugar and salt; taxing sugary drinks, and providing better access to affordable, healthy food. In our cities and towns, we need to make space for safe walking, cycling, and recreation. We must teach our children healthy habits from early on.

\r\n\r\n

WHO is responding to the global obesity crisis on many fronts, including monitoring global trends and prevalence, the development of a broad range of guidance addressing the prevention and treatment of overweight and obesity, and providing implementation support and guidance such as the Report of the Commission on Ending Childhood Obesity.

\r\n\r\n

\r\n","createDate":"2020-03-04T14:55:00","status":1,"picture":"https://cdn.clinicways.com/news/e2a420da-262c-485e-9d43-5ad936608405/Main.JPEG","guid":"e2a420da-262c-485e-9d43-5ad936608405","newsType":1,"seoUrl":"world-obesity-day","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"World obesity day encourages practical solutions to help people achieve and maintain a healthy weight, undertake proper treatment, and reverse the obesity crisis.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.who.int/news-room/events/detail/2020/03/04/default-calendar/world-obesity-day","categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":132,"title":"10 things you should know before a gastric sleeve surgery","newsContent":"

1.Obesity is a disease with different causes,

\r\n\r\n

Although obesity appears to be an aesthetic problem in society, the WHO defines obesity as a disease with serious complications. Obesity surgery is the most effective and well-known method of treating obesity.

\r\n\r\n

2. A Surgery is no wonder.

\r\n\r\n

\r\n

\r\n\r\n

Obesity surgery is no wonder and the surgeons are not magicians. This surgery is a great help to get used to the right routines and lose weight successfully.
\r\n

\r\n\r\n

3. The aftercare process is as important as the surgical success of the surgeon you are operated on.

\r\n\r\n

It is important to have correct information after an obesity surgery. In addition, nobody can be expected to become an expert with a short information. The support and accessibility of a specialist who can provide accurate information about the problems that may arise after the operation is very important. This is necessary in order not to have any problems with losing weight and to be able to protect your weight after many years. Even if you lose weight in a short period of time, this is necessary to avoid problems in the process of losing weight and to be able to keep your weight after many years.

\r\n\r\n

4. Answer the opinions of your family and friends appropriately.

\r\n\r\n

The bad reputation of the methods that are gradually being abandoned today has led to a tendency against obesity surgery. In general, family members and friends who do not consider obesity to be a disease and are afraid of losing their relatives may initially rate the surgery negatively. Those who wish in the postoperative period you had the surgery earlier, will likely be the same people. When they learn from the right sources and understand that obesity is a disease to be treated, their negative will opinions change.

\r\n\r\n

5. Remember that you have to change your old habits together with your old life.

\r\n\r\n

Instead of thinking about, why I should be operated on, if I have to be careful anyway, you should think that you will create successfully new habits with the operation. If you intend to continue what you did before the surgery, you should know that surgery is not a diet program and to keep your weight at a healthy level in the long term depends to your desire for change.

\r\n\r\n

6. You are not alone.
\r\n

\r\n\r\n

Every year, thousands of people around the world resort to surgery, the most effective way to solve the obesity problem. People with obesity problems may no longer feel like short-term success and unsuccessful processes, that will later lead to weight gain, and may no longer believe, that they will lose weight in any way. You should know, that almost everyone who prefers obesity surgery, has experienced such a process of experience and that many have managed to reach a permanent weight level in the end.
\r\n

\r\n\r\n

7. If you are unsure, postpone the operation.

\r\n\r\n

If you have any doubts about the operation, you should eliminate them before the operation. The process is not very difficult, but nobody can say that it is easy. Of course, you can never be 100% ready for it. However, the answering of important points and questions, will increase your motivation and reduces stress. Unanswered questions and unresolved doubts can make easy problems seem difficult.

\r\n\r\n

8 . Get ready for a new life and not for a lifelong diet.

\r\n\r\n

The most important peculiarity of obesity surgery is that it helps you to get the right eating and lifestyle habits. Thanks to physical and hormonal changes, you can achieve a healthy and ideal weight for your whole life by following certain rules. You will not go on a diet for life. However, a lifelong healthy nutrition applies to you, just as for everyone else. Get ready for changes, not for diets!!!

\r\n\r\n

9. Don't be afraid.
\r\n

\r\n\r\n

If there is something to be afraid of, it is not the surgery, but the obesity. Obesity surgery is not an arbitrary aesthetic operation Hundreds of thousands of people undergo successfully obesity surgery every year. Of course, there is no zero risk. As with any operation, these operations involve risks. These risks are assessed by the surgeon correctly and it is decided if you can have surgery or not.

\r\n\r\n

10. Make sure you get your information from the right source.

\r\n\r\n

As in all areas, there is information pollution about obesity surgery too. The best way to access correct information is to consult experts in the field and review the sources of information. Various scientific studies on obesity surgery in the world are published daily. In particular, you should check the accuracy of the personal comments and information you have received from social media.

\r\n\r\n

Test immediately for free whether you are eligible for obesity surgery.

\r\n\r\n

Please call us for detailed information.

\r\n","createDate":"2020-03-02T09:55:00","status":1,"picture":"https://cdn.clinicways.com/news/9a2389d0-01fa-4eb3-85d6-94ddc8ed426c/Main.JPEG","guid":"9a2389d0-01fa-4eb3-85d6-94ddc8ed426c","newsType":1,"seoUrl":"10-things-you-should-know-before-a-gastric-sleeve-surgery","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"10 things to know before an obesity surgery","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":128,"title":"Your waist size may be more important than weight for multiple heart attack risk","newsContent":"

Heart attack survivors who carry extra weight around their belly are at greater risk of another heart attack, new research has found, another reason why measuring your waist may be more important than stepping on the scale.

\r\n\r\n

It's been known for a while that having a pot belly, even if you are slim elsewhere, increases the odds of having a first heart attack, but the latest study, which published Monday in the European Journal of Preventative Cardiology, is the first time researchers have found a link between belly fat and the risk of a subsequent heart attack or stroke.

\r\n\r\n

The link was particularly strong in men, researchers said.

\r\n\r\n

\r\n\r\n\r\n

"Abdominal obesity not only increases your risk for a first heart attack or stroke, but also the risk for recurrent events after the first misfortune," said Dr. Hanieh Mohammadi of the Karolinska Institute in Stockholm, in a news release.

\r\n\r\n

"Maintaining a healthy waist circumference is important for preventing future heart attacks and strokes regardless of how many drugs you may be taking or how healthy your blood tests are."

\r\n\r\n

The study tracked more than 22,000 Swedish patients after their first heart attack and looked at the link between their waist circumference and events caused by clogged arteries like fatal and non-fatal heart attacks and stroke. Patients were followed for nearly four years, with 1,232 men (7.3%) and 469 women (7.9%) experiencing a heart attack or stroke.

\r\n\r\n

Most patients — 78% of men and 90% of women — had abdominal obesity, defined as a waist circumference of 94 cm (37.6 inches) or above for men, and 80 cm (32 inches) or above for women.

\r\n\r\n

The study found that belly fat was associated with heart attacks and stroke independent of other risk factors like smoking, diabetes, hypertension, body mass index and prevention treatments. The researchers stressed that waist circumference was a more important marker than overall obesity and advised doctors to measure their patient's waists to identify those at risk.

\r\n\r\n

However, they said that the link was stronger and more linear in men, who made up nearly three-fourths of the patients included in the study, than women.

\r\n\r\n

In women, Mohammadi said the relationship was "U-shaped" rather than linear, meaning that the mid-range waist measurement, rather than the narrowest, was least risky. What's more, the mid-range waist measurement was in the range traditionally recognized as at risk for abdominal obesity: more than 80 cm wide.

\r\n\r\n

The reason for this could be down to the type of fat that tends to hang out on men's and women's bellies. Mohammadi said some studies have suggested that men may have more visceral fat that goes deep inside your body and wraps around your vital organs.

\r\n\r\n

This fat can be turned into cholesterol that can start collecting along and hardening your arteries, perhaps ultimately leading to a heart attack or stroke.

\r\n\r\n

"In women it is thought that a greater portion of the abdominal fat is constituted by subcutaneous fat which is relatively harmless," she said.

\r\n\r\n

However, the lower numbers of women included in the study meant the findings had less "statistical power" and more research was needed to draw definite conclusions, Mohammadi said.

\r\n\r\n

\r\n\r\n\r\n

The risk of cardiovascular disease like heart attacks or strokes is considered to be higher in those with a waist measurement of above 94 cm in men and above 80 cm in women, according to the World Health Organization. The risk is thought to be substantially increased in men with a waist wider than 102 cm and 88 cm in women.

\r\n\r\n

The authors said that belly fat was best tackled by a healthy diet and regular exercise. Earlier studies have shown that regular moderate cardio, like walking for at least 30 minutes a day, can help fight a widening waistline. Strength training with weights may also help but spot exercises like sit-ups that can tighten abs won't touch visceral fat.

\r\n\r\n

You can solve our test to calculate the ideal waist circumference

\r\n","createDate":"2020-02-25T08:21:00","status":1,"picture":"https://cdn.clinicways.com/news/7b3c9b6c-d47a-4edb-9b25-6831cc8cd9b8/Main.JPG","guid":"7b3c9b6c-d47a-4edb-9b25-6831cc8cd9b8","newsType":1,"seoUrl":"your-waist-size-may-be-more-important-than-weight-for-multiple-heart-attack-risk","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Heart attack survivors who carry extra weight around their belly are at greater risk of another heart attack.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://edition.cnn.com/","categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":125,"title":"Can you dance your way to better health and well-being? For the first time, WHO studies the link between arts and health","newsContent":"

Engaging with the arts can be beneficial for both mental and physical health. This is a key conclusion of a new report from the WHO Regional Office for Europe analysing the evidence from over 900 global publications – the most comprehensive review of evidence on arts and health to date.

\r\n\r\n

“Bringing art into people’s lives through activities including dancing, singing, and going to museums and concerts offers an added dimension to how we can improve physical and mental health,” says Dr Piroska Östlin, WHO Regional Director for Europe a.i.
\r\n“The examples cited in this groundbreaking WHO report show ways in which the arts can tackle ‘wicked’ or complex health challenges such as diabetes, obesity and mental ill health. They consider health and well-being in a broader societal and community context, and offer solutions that common medical practice has so far been unable to address effectively,” Dr Östlin explains.

\r\n\r\n

The report reviews arts activities that seek to promote health and prevent ill health, as well as manage and treat physical and mental ill health and support end-of-life care. It will be launched on Monday, 11 November at 08:00 CET during an event in Helsinki, Finland, which will bring together experts, policy-makers, practitioners and service users to discuss the role of arts interventions in health care. The event will be live-streamed.

\r\n\r\n

Arts and health throughout life

\r\n\r\n

From before birth to the end of life, the arts can positively influence health. For example, young children whose parents read to them before bed have longer night-time sleep and improved concentration at school. Among adolescents living in urban areas, drama-based peer education can support responsible decision-making, enhance well-being and reduce exposure to violence. Later in life, music can support cognition in people with dementia – singing in particular has been found to improve attention, episodic memory and executive function.

\r\n\r\n

Arts in health care

\r\n\r\n

In health-care settings, arts activities can be used to supplement or enhance treatment protocols. For example:

\r\n\r\n

listening to music or making art have been found to reduce the side effects of cancer treatment, including drowsiness, lack of appetite, shortness of breath and nausea;
arts activities in emergency settings, including music, crafts and clowning, have been found to reduce anxiety, pain and blood pressure, particularly for children but also for their parents; and
dance has been found repeatedly to provide clinically meaningful improvements in motor scores for people with Parkinson’s disease.

\r\n\r\n

The report highlights that some arts interventions not only produce good results, but can also be more cost-effective than more standard biomedical treatments. They can combine multiple health-promoting factors at once (such as physical activity and mental health support) and have a low risk of negative outcomes. Because arts interventions can be tailored to have relevance for people from different cultural backgrounds, they can also offer a route to engage minority or hard-to-reach groups.

\r\n\r\n

Several countries are now looking to arts and social prescribing schemes, whereby primary-care doctors can refer their patients to arts activities.

\r\n\r\n

Policy considerations

\r\n\r\n

The report outlines policy considerations for decision-makers in the health sector and beyond, such as:

\r\n\r\n

ensure the availability and accessibility of arts-for-health programmes within communities;
support arts and cultural organizations in making health and well-being part of their work;
promote public awareness of the potential health benefits of arts engagement;
include arts in the training of health-care professionals;
introduce or strengthen referral mechanisms from health- or social-care facilities to arts programmes or activities; and
invest in more research, particularly in scaling up arts and health interventions, and evaluating their implementation.

\r\n\r\n

Definition of “arts”

\r\n\r\n

The report reviewed the health benefits (either through active or passive participation) in five broad categories of arts: performing arts (music, dance, singing, theatre, film); visual arts (crafts, design, painting, photography); literature (writing, reading, attending literary festivals); culture (going to museums, galleries, concerts, the theatre); and online arts (animations, digital arts, etc.).
\r\n

\r\n","createDate":"2020-02-06T13:03:00","status":1,"picture":"https://cdn.clinicways.com/news/1035a474-23d2-44f6-afe6-fdb90129bc2c/Main.JPEG","guid":"1035a474-23d2-44f6-afe6-fdb90129bc2c","newsType":1,"seoUrl":"can-you-dance-your-way-to-better-health-and-well-being-for-the-first-time-who","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Engaging with the arts can be beneficial for both mental and physical health. This is a key conclusion of a new report from the WHO Regional Office for Europe analysing...","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"http://www.euro.who.int/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":122,"title":"New WHO studies: Europe battles childhood obesity and experts confirm breastfeeding protects against child obesity","newsContent":"

A new study from WHO/Europe shows that, despite efforts aimed at prevention, parts of the WHO European Region continue to struggle with comparably higher rates of childhood obesity, while a second study shows that babies who have never or only infrequently been breastfed have an increased risk of becoming obese as children.

\r\n\r\n

Progress on tackling the childhood obesity crisis has been slow and inconsistent throughout the Region, according to the 2 studies released at this year’s European Congress on Obesity in Glasgow, United Kingdom.

\r\n\r\n

“The longer a child is breastfed, the greater their protection from obesity. This knowledge can strengthen our efforts in preventing obesity. Acting on childhood obesity – including severe obesity – can have major benefits, not only for child health and well-being, but also for national health care systems, so we must do all we can to promote and protect breastfeeding across the Region,” said Dr Bente Mikkelsen, Director of the Division of Noncommunicable Diseases and Promoting Health through the Life-course, WHO/Europe.

\r\n\r\n

Consequences of severe obesity

\r\n\r\n

Severe obesity in children is associated with immediate and long-term cardiovascular, metabolic and other negative health outcomes. When comparing overweight children to children with severe obesity, the latter have a much worse cardio-metabolic risk factor profile. According to the new WHO study, “Prevalence of severe obesity among primary school children in 21 European countries”, severe obesity affects almost 400 000 of the roughly 13.7 million children aged 6–9 years living in the 21 participating countries.

\r\n\r\n

This study is the first that investigates the prevalence of severe obesity in school children. Severe obesity is a serious public health issue and the results of this study show that a large number of children in the European Region suffer from it. Given its impact on education, health, social care and the economy, the new report emphasizes that obesity needs to be addressed via a range of approaches, from prevention to early diagnosis and treatment.

\r\n\r\n

Link between breastfeeding and obesity

\r\n\r\n

The second study, “Association between characteristics at birth, breastfeeding and obesity, in 22 countries”, found that despite the consistent flow of research evidence showing the health benefits from breastfeeding, along with numerous policy initiatives aimed at promoting optimal breastfeeding practices, adoption of exclusive breastfeeding in the European Region remains below the global recommended level.

\r\n\r\n

WHO recommends exclusive breastfeeding for the first 6 months of life. Thereafter, infants should be given nutritionally adequate complementary foods with continued breastfeeding up to 2 years of age or beyond.

\r\n\r\n

This study showed that, in nearly all countries, more than 77% of children were breastfed; but there were a few exceptions – in Ireland 46% of children were never breastfed, in France 38% and in Malta 35%. Only 4 out of 12 countries had a prevalence of exclusive breastfeeding (for 6 months or more) of 25% or higher: Tajikistan (73%), Turkmenistan (57%), Kazakhstan (51%) and Georgia (35%).

\r\n\r\n

According to the study, breastfeeding practices in the Region fall short of WHO recommendations for a number of reasons, including: inefficient policies to encourage breastfeeding, lack of preparation of health professionals to support breastfeeding, intensive marketing of breast milk substitutes, and problems in legislation on maternity protection.

\r\n\r\n

“The promotion of breastfeeding presents a window of opportunity for obesity prevention policy to respond to the problem of childhood obesity in the European Region. Existing national policies to promote breastfeeding practices and how these policies are developed, can lead some countries to be more or less successful in combating obesity,” said Dr Joao Breda, Head of the WHO European Office for Prevention and Control of Noncommunicable Diseases, who also led the WHO Childhood Obesity Surveillance Initiative, known as COSI. Research from this initiative was used for both reports.

\r\n\r\n

COSI was established more than 10 years ago to estimate prevalence and monitor changes in overweight and obesity in children aged 6–9 years. Since then, there have been 5 rounds of data collection in more than 40 countries and among more than half a million children.

\r\n","createDate":"2020-02-06T13:01:00","status":1,"picture":"https://cdn.clinicways.com/news/96007f9e-400d-41ba-8f2c-f090c4173330/Main.JPEG","guid":"96007f9e-400d-41ba-8f2c-f090c4173330","newsType":1,"seoUrl":"new-who-studies-europe-battles-childhood-obesity-and-experts-confirm-breastfeed","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"A new study from WHO/Europe shows that, despite efforts aimed at prevention, parts of the WHO European Region continue to struggle with comparably higher rates of childhood obesity...","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"http://www.euro.who.int/","categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":119,"title":"German pediatricians push for sugar tax to combat rising obesity","newsContent":"

A look abroad shows that this is an effective approach, BVKJ President Thomas Fischbach told DPA.

\r\n\r\n

"With the introduction of sugar taxes - and thus higher prices - consumers there have largely lost their appetite for sweets, and the sales figures for sweet drinks have declined significantly since the introduction of the tax.”

\r\n\r\n

The so-called alcopops tax - or tax on sweet alcoholic drinks - has demonstrated that legal bans on food products can work in Germany, he added.

\r\n\r\n

"After politicians imposed a special tax on the mixed liquor drinks popular with young people (in 2004), sales fell by 80 percent within one year,” said Fischbach.

\r\n\r\n

“This example, but also the examples of Mexico, France, Finland, Hungary and Great Britain, show that control mechanisms can effectively protect health.”

\r\n\r\n

The World Health Organization (WHO) has called childhood obesity a growing problem in Germany. They found that 6.9 percent of girls and 11.2 percent of boys between the ages of five and 19 were obese in 2016.

\r\n\r\n

The WHO called for advertising on sweet products and junk food to be better regulated as “young people are very susceptible to advertising up until the age of 16,” the WHO wrote in a statement.

\r\n\r\n

Half of all adults in Germany are overweight, according to the latest statistics released by Federal Nutrition Minister Julia Klöckner.

\r\n\r\n

$\"adipositas$

\r\n\r\n

"Its effectiveness has been proven in numerous scientific studies,” said Fischbach. “Parents will find it easier to provide healthy food for their children in the future.”

\r\n\r\n

In addition to listing a product's sugar, fat and salt content, Nutri-Score also includes features fibre and protein in an overall score assigned a rating - on a five-letter scale from a dark green 'A' to a red 'E' for the least favourable.

\r\n\r\n

For example, 'E' products with a high sugar and fat content which should usually be avoided, said Klöckner when presenting the system in late September.

\r\n\r\n

The new logo is intended to supplement the EU-wide nutrition table, which is usually printed on the back of packs.

\r\n\r\n

The first products with the new logo are already beginning to appear in German supermarkets. The label is not mandatory, however, and food producers can decide themselves whether they want to include it on their products.

\r\n","createDate":"2020-01-13T10:17:00","status":1,"picture":"https://cdn.clinicways.com/news/ecf22fb5-05a9-46ad-b6c0-a35fce25deb1/Main.JPEG","guid":"ecf22fb5-05a9-46ad-b6c0-a35fce25deb1","newsType":1,"seoUrl":"german-pediatricians-push-for-sugar-tax-to-combat-rising-obesity","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Germany's Professional Association of Pediatricians and Youth Physicians (BVKJ) on Monday called for the introduction of a sugar tax to tackle rising obesity among young people.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.thelocal.de/","categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":116,"title":"Study finds dopamine, biological clock link to snacking, overeating and obesity","newsContent":"

During the years 1976 through 1980, 15% of U.S. adults were obese. Today, about 40% of adults are obese. Another 33% are overweight.

\r\n\r\n

Coinciding with this increase in weight are ever-rising rates of heart disease, diabetes, cancer and health complications caused by obesity, such as hypertension. Even Alzheimer's disease may be partly attributable to obesity and physical inactivity.

\r\n\r\n

"The diet in the U.S. and other nations has changed dramatically in the last 50 years or so, with highly processed foods readily and cheaply available at any time of the day or night," Ali Güler, a professor of biology at the University of Virginia, said. "Many of these foods are high in sugars, carbohydrates and calories, which makes for an unhealthy diet when consumed regularly over many years."

\r\n\r\n

In a study published Thursday in the journal Current Biology, Güler and his colleagues demonstrate that the pleasure center of the brain that produces the chemical dopamine, and the brain's separate biological clock that regulates daily physiological rhythms, are linked, and that high-calorie foods -- which bring pleasure -- disrupt normal feeding schedules, resulting in overconsumption. Using mice as study models, the researchers mimicked the 24/7 availability of a high-fat diet, and showed that anytime snacking eventually results in obesity and related health problems.

\r\n\r\n

Güler's team found that mice fed a diet comparable to a wild diet in calories and fats maintained normal eating and exercise schedules and proper weight. But mice fed high-calorie diets laden with fats and sugars began "snacking" at all hours and became obese.

\r\n\r\n

Additionally, so-called "knockout" mice that had their dopamine signaling disrupted -- meaning they didn't seek the rewarding pleasure of the high-fat diet -- maintained a normal eating schedule and did not become obese, even when presented with the 24/7 availability of high-calorie feeds.

\r\n\r\n

"We've shown that dopamine signaling in the brain governs circadian biology and leads to consumption of energy-dense foods between meals and during odd hours," Güler said.

\r\n\r\n

Other studies have shown, Güler said, that when mice feed on high-fat foods between meals or during what should be normal resting hours, the excess calories are stored as fat much more readily than the same number of calories consumed only during normal feeding periods. This eventually results in obesity and obesity-related diseases, such as diabetes.

\r\n\r\n

Speaking of the modern human diet, Güler said, "The calories of a full meal may now be packed into a small volume, such as a brownie or a super-size soda. It is very easy for people to over-consume calories and gain excessive weight, often resulting in obesity and a lifetime of related health problems.

\r\n\r\n

"Half of the diseases that affect humans are worsened by obesity. And this results in the need for more medical care and higher health care costs for individuals, and society."

\r\n\r\n

Güler said the human body, through thousands of years of evolution, is hard-wired to consume as much food as possible as long as it's available. He said this comes from a long earlier history when people hunted or gathered food and had brief periods of plenty, such as after a kill, and then potentially lengthy periods of famine. Humans also were potential prey to large animals and so actively sought food during the day, and sheltered and rested at night.

\r\n\r\n

"We evolved under pressures we no longer have," Güler said. "It is natural for our bodies as organisms to want to consume as much as possible, to store fat, because the body doesn't know when the next meal is coming.

\r\n\r\n

"But, of course, food is now abundant, and our next meal is as close as the kitchen, or the nearest fast-food drive-through, or right here on our desk. Often, these foods are high in fats, sugars, and therefore calories, and that's why they taste good. It's easy to overconsume, and, over time, this takes a toll on our health."

\r\n\r\n

Additionally, Güler said, prior to the advent of our electricity-powered society, people started the day at dawn, worked all day, often doing manual labor, and then went to sleep with the setting of the sun. Human activity, therefore, was synchronized to day and night. Today, we are working, playing, staying connected -- and eating -- day and night. This, Guler said, affects our body clocks, which were evolved to operate on a sleep-wake cycle timed to daytime activity, moderate eating and nighttime rest.

\r\n\r\n

"This lights-on-all-the-time, eat-at-any-time lifestyle recasts eating patterns and affects how the body utilizes energy," he said. "It alters metabolism -- as our study shows -- and leads to obesity, which causes disease. We're learning that when we eat is just as important as how much we eat. A calorie is not just a calorie. Calories consumed between meals or at odd hours become stored as fat, and that is the recipe for poor health."

\r\n\r\n

The National Institute of General Medical Sciences and University of Virginia Brain Institute funded the research.

\r\n\r\n

\r\n

Story Source:

\r\n\r\n

Materials provided by University of Virginia. Note: Content may be edited for style and length.

\r\n","createDate":"2020-01-13T08:22:00","status":1,"picture":"https://cdn.clinicways.com/news/96d8ceaf-2d5f-4b31-ac49-befb3fa6a835/Main.JPEG","guid":"96d8ceaf-2d5f-4b31-ac49-befb3fa6a835","newsType":1,"seoUrl":"study-finds-dopamine-biological-clock-link-to-snacking-overeating-and-obesity","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"A new study finds that the pleasure center of the brain and the brain's biological clock are linked, and that high-calorie foods -- which bring pleasure -- disrupt normal feeding schedules, resulting in overconsumption.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.sciencedaily.com/","categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":113,"title":"Why do skin sagging?","newsContent":"

Why do skin sagging?

\r\n\r\n

The largest organ in our body is the skin. The skin is very flexible and adaptable. Proteins such as collagen and elastin lead to the strengthening, flexibility, tightening and tension of the skin. There are various reasons for sagging skin. There is usually a decrease in elasticity with age and sagging of the skin due to gravity. Weight loss also leads to sagging of the skin. The fat under the tissue decreases, the skin cannot shrink and loses its elasticity, which leads to sagging of the skin. As an example: The skin expands and enlarges due to weight gain and fat formation.
\r\nWhen it comes to weight loss, the limit of skin tightening ability is affected. The excess fat in the stomach area increases like a balloon and tightens the skin. If you now burn these fats (lose weight), the skin cannot return to its original state. Over time, the skin loses its flexibility and the interaction of the abdominal muscles with the skin diminishes.

\r\n\r\n

What are the factors of skin sagging?

\r\n\r\n

Sagging of the skin can occur after the bariatric procedure and is considered a disadvantage of the operation. While there is a lot of different research on the subject, there are many more to come.

\r\n\r\n

Age
\r\nWith age, there is a reduction in skin elasticity and gravity causes sagging of the skin.

\r\n\r\n

Too high proportion of weight
\r\nThe higher your body weight is above the ideal weight, the bigger the skin is tightened and enlarged.
\r\nTherefore it will be very difficult to reach the starting point.

\r\n\r\n

Many fluctuations in weight
\r\nWeight fluctuations over many years negatively affect skin elasticity.

\r\n\r\n

Rapid weight change
\r\nThe rapid increase and decrease affects the adaptability of the skin. Do not forget; the skin is a living organ.

\r\n\r\n

Cigarettes
\r\nCigarettes cause the skin to age quickly. Wrinkles and sagging become visible.

\r\n\r\n

Diet and water intake
\r\nMainly water supply, proteins rich in collagen, vitamin A for protection from the sun, vitamin C for the formation of collagen, vitamin E with the property for antioxidation, vitamin B for vitality, zinc, omega-3, omega-6.

\r\n\r\n

Genetic factors
\r\nGenetic factors play a big role. Some people do not take any measures and there are no sagging skin, others take measures and there are still sagging skin.

\r\n\r\n

Sport, exercises
\r\nThe living organ, the skin, renews its cells with exercise and exercises. The muscle build-up creates tension under the skin.

\r\n\r\n

Exposure to the sun
\r\nExcessive amounts of sunlight damage our skin from harmful UV rays. These lead to skin spots etc.

\r\n\r\n

Pregnancy
\r\nPregnancy can cause skin sagging, especially in the abdomen.

\r\n\r\n

\r\nNegative effects of post-operative bariatric surgery

\r\n\r\n

According to research, most skin sagging occurs on the abdomen, upper arm, inner thighs and chest. Skin sagging can also occur on the cheeks, on the upper part of the back and above the knee. If the preoperative BMI (Body Mass Index) is high and weight loss occurs quickly, the skin is more likely to sag. It has been shown that women are more uncomfortable with sagging skin than men. It has also been reported that patients who underwent bariatric surgery during puberty may experience psychological problems due to sagging skin.

\r\n\r\n

Sagging skin is often equated with "wrinkles" and "flaccidity". Patients feel ashamed of it or no longer feel like it. Many choose clothes that they can use to hide their belly and arms. Some prefer loose pants, women try to hide the breast area with the bra.
\r\nSome patients (0.1%) find the sagging skin to be significantly worse and more embarrassing than being obese. Approximately 40% of postoperative bariatric patients report sagging skin causing problems with fungal infections, eczema and abdominal lesions, breasts and / or groins, and unpleasant smells, itching, sweating, and personal hygiene issues.

\r\n\r\n

Sagging skin has also been reported as an obstacle to privacy and sexual intercourse. Patients feel the excess skin is something impersonal and do not think they belong to them. This also affects self-esteem. Some patients may have problems participating in physical activities, hobbies, and social
\r\nExperiencing activities due to sagging skin, even though they have a large weight loss

\r\n\r\n

Biochemicker - bariatric life guide

\r\n\r\n

Alper Habip

\r\n\r\n

The following sources were used in the preparation of this article.

\r\n\r\n

1. Silke K. Schagen, 1, Vasiliki A. Zampeli et al. Discovering the link between nutrition and skin aging - Dermatoendocrinol. 2012 Jul 1; 4 (3): 298-307. doi: 10.4161 / derm.22876

\r\n\r\n

2. Baillot A, Asselin M, Comeau E, Meziat-Burdin A, Langlois MF. Impact of excess skin from massive weight loss on the practice of physical activity in women. Obes Surg 2013; 23 (11): 1826-34.

\r\n\r\n

3. M.A. Farage, K.W. Miller, et.al. Intrinsic and extrinsic factors in skin aging: a review International Journal of Cosmetic Science Volume 30, Issue 2 Pages 79-154 - April 2008

\r\n\r\n

4. Christina Biörserud, Excess Skin After Bariatric Surgery, Patients ’perspective and objective measurements, Department of Surgery, Institute of Clinical Science Sahlgrenska Academy at University of Gothenburg Gothenburg, Sweden 2015

\r\n","createDate":"2020-01-11T18:30:00","status":1,"picture":"https://cdn.clinicways.com/news/2b2b052d-f446-4dfb-a8af-c7b8bf5275f3/Main.JPEG","guid":"2b2b052d-f446-4dfb-a8af-c7b8bf5275f3","newsType":1,"seoUrl":"why-do-skin-sagging","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"The largest organ in our body is the skin. The skin is very flexible and adaptable. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.hayatiyenile.org/","categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":110,"title":"Bariatric surgery on social media","newsContent":"

Bariatric surgery, popularized with low complication rates, effective weight loss, increasing obesity rates, economic attractiveness, inadequate control, and so on, is likely to be spoken mainly on social media. The increasing number of patients who have experienced gastric stomach or other bariatric surgery and the desire of doctors to do "more" (surgery) are causing some scientific and unethical situations. In other words, a person who has had an operation can view their personal experience as a scientific reality and share it with people through social media and various means. Furthermore, it is an undeniable fact that they made financial gains from this work by making them "coordinators". Now almost every doctor has a "coordinator". Of course there are people who do their work with medical, scientific and ethical values.

\r\n\r\n

I think social media is an important part of bariatric surgery and I want to share the research on it with you. But before that, I want to give you some suggestions for preventing information pollution and give you tips on how to confirm the accuracy of information;

\r\n\r\n

\r\n1. Ask the question correctly

\r\n\r\n

Example 1: Ohhh my hair falls out, what should I do?

\r\n\r\n

Example 2: I want to smoke, today is my second day, should I smoke ??

\r\n\r\n

Example 3: Can I eat kebab during the porridge phase?

\r\n\r\n

Avoid such questions as they will inevitably harm you. Thousands of people see these questions, of course there will be people who smoke and have no problems with it. There will also be people who can find a solution to their own hair loss problems, but they can harm you. But don't forget that some applications can even endanger your life. (e.g. for someone with low iron levels, iron supplements can reduce hair loss, but can lead to iron poisoning in other people). Instead of asking these questions, you can ask questions that increase your motivation: for example, if you have a hair loss problem and want to examine it, it is more correct to ask your question this way.

\r\n\r\n

Example 1: Why do my hair start to fall? What kind of solutions can I use? How does your doctor treat you? Can you give me a source that I can read?

\r\n\r\n

Example 2: I want to smoke. What can I do to reduce this craving? How did you deal with this situation?

\r\n\r\n

Example 3: I feel like kebab. Do you have any recipe suggestions for the porridge phase that can reduce this craving?

\r\n\r\n

\r\n2. Examine the science of answers

\r\n\r\n

Remember that any information, including the information here, requires clarity, that science does not operate with absolute integrity, and that it must be evident in scientific publications, even from a famous professor of information that you receive , Scientists and successful doctors base their knowledge on scientific resources. Make sure that you question the source of information that you get from social media (the doctor may have given the patient other information and the patient can tell you how they perceive it). Stay away from those who are trying to give you advice on what is unclear to the source.

\r\n\r\n

Example 1: I moistened my hair with mineral water. It felt good.

\r\n\r\n

Example 2: I lit a cigarette right after the operation, nothing happened.

\r\n\r\n

Example 3: I ate, nothing happened.

\r\n\r\n

Example 1: I stir a cream with radish and olive oil and put it in my hair. It is very good.

\r\n\r\n

Example 2: I put some ginger in the water. That reduces my need to smoke.

\r\n\r\n

Example 3: I don't want to eat kebab when I drink broth. When you feel full, you don't feel like eating.

\r\n\r\n

\r\n3. Consult your doctor first

\r\n\r\n

If you cannot reach your doctor, try to contact another doctor. If you can't do anything, research the side effects and disadvantages of using it from many different and scientific sources. Never try to use applications that could cause side effects without consulting your doctor. Your pharmacist can help you with this.

\r\n\r\n

The importance of social media in bariatric surgery

\r\n\r\n

Long-term support after bariatric surgery is critical to success. Many people who have had surgery go to support groups and social media such as Facebook in particular. Little is known about the actual content of these groups. (1)

\r\n\r\n

In a study conducted in the United States in 2016, surveys on bariatric surgery on Facebook pages and groups were followed for a month. At the end of the month, over 6,800 messages and replies were analyzed and broken down into their content (depression, development, eating behavior were securely coded).

\r\n\r\n

As a result, these messages and replies were found to be the most common types of messages and replies. (1)

\r\n\r\n

53% - information and advice
\r\n19% - comment on postoperative changes
\r\n32% - support from other members

\r\n\r\n

Anxiety, eating behavior, depression, body image, weight prejudice, and alcohol-related issues were found to be less common. (1)

\r\n\r\n

Scientific assessments are made on the Internet by bariatric surgical groups to receive support, to celebrate by sharing physical and emotional achievements, to have knowledge of the "bariatric lifestyle" for preoperative patients, to exchange motivation and information. The people who build and manage these groups should keep a close eye on everything. (1)

\r\n\r\n

Biochemist- bariatric life coach
\r\nAlper Habip

\r\n\r\n

1. Afton M.Koball,Ph.D.,A.B.P.P.a,*, DylanJ.Jester,B.S.b, SarahE.Domoff,Ph.D.c,d, Kara J.Kallies,M.S.b, KarenB.Grothe,Ph.D.,A.B.P.P.e, Shanu N.Kothari,M.D.,F.A.C.S.,F.A.S.M.B.S.f / Surgery for Obesity and Related Diseases ] (2017) 00–00, Examination of bariatric surgery Facebook support groups: a content analysis , April 24 , 2017

\r\n\r\n

aDepartment ofBehavioralHealth,GundersenHealthSystem,LaCrosse,Wisconsin

\r\n\r\n

bDepartment ofMedicalResearch,GundersenMedicalFoundation,LaCrosse,Wisconsin cDepartmentofPsychology,CentralMichiganUniversity,MountPleasant,Michigan

\r\n\r\n

dCenter forHumanGrowthandDevelopment,UniversityofMichigan,AnnArbor,Michigan eDepartmentofPsychiatryandPsychology,MayoClinic,Rochester,Minnesota

\r\n\r\n

fDepartmentofGeneralSurgery,GundersenHealthSystem,LaCrosse,Wisconsi

\r\n","createDate":"2020-01-11T10:38:00","status":1,"picture":"https://cdn.clinicways.com/news/1cca4041-72ee-47b6-a7b8-036a966c7c6a/Main.JPEG","guid":"1cca4041-72ee-47b6-a7b8-036a966c7c6a","newsType":1,"seoUrl":"bariatric-surgery-on-social-media","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Bariatric surgery, popularized with low complication rates, effective weight loss, increasing obesity rates, economic attractiveness, inadequate control, and so on, is likely to be spoken mainly on social media.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.hayatiyenile.org/","categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":107,"title":"Hair Loss After Sleeve Gastrektomy","newsContent":"

One of the most common problems after bariatric surgery is hair loss. Hair loss, which usually occurs between the 3rd and 9th month after surgery, is in fact not a health problem and is temporary. However, if the appearance and psychological factors are taken into account, hair loss requires intervention.

\r\n\r\n

A small amount of hair loss is a common problem, usually about three months or more after the operation, and affects about a third of the patients. The exact reasons for this hair loss are not known. However, it is believed that bariatric surgery leads to changes in nutritional status and is attributed to nutritional restrictions and the hair growth cycle.

\r\n\r\n

After weight stabilization, new hair growth occurs without any intervention.

\r\n\r\n

Structure of human hair

\r\n\r\n

\r\nThe hair consists mainly of protein and keratin. It also contains lipids (oil), water, pigments and trace elements. In the picture below you can see the anatomical structure and parts of the hair.

\r\n\r\n

\r\nHair Growth Cycle

\r\n\r\n

Hair growth typically follows a three-step cycle.
\r\nDuring the anagen or growth phase, cell division in the papilla ensures an extension of the hair shaft and new growth from the hair root upwards. The anagen phase can last 2-10 years, but usually lasts only 3-5 years. During this time, the hair grows 1-1.5 cm a month. This time and growth rate can be influenced by genetic, hormonal and metabolic factors. It can also respond to seasonal changes. Typically, 80% to 90% of hair is in the anagen phase when viewed at all times. At the end of the anagen phase, the hair enters the transition period called catagen.

\r\n\r\n

Mitosis (division) stops in the catagen phase. The hair follicle is scarred and the food source is cut out of the papilla (root). The formation of the medulla and cuticle ends. This phase lasts about 1 to 2 weeks. Only 1% of your hair is in this phase at all times.

\r\n\r\n

The telogen phase is the stagnation phase. The hair follicle stagnates for 1-4 years until the anagen begins again. Old hair is pushed down by the follicle because new hair grows in the roots.

\r\n\r\n

There are about 100,000 hairs in a healthy human skull, and 100 of them fall out every day. Each hair stays for 1 to 6 years. There is always new growth.

\r\n\r\n

How to identify hair loss

\r\n\r\n

Hair loss after bariatric surgery usually occurs after 3-6 months, depending on various reasons, this period can sometimes take longer. The diagnosis is usually made through a medical history and clinical examination with significantly increased hair loss, accompanying symptoms such as skin and nail abnormalities and the use of certain medications. Various tests can be done if there is any doubt as to the nature or cause of the hair loss. If necessary, hair follicles can be taken for microscopic examination, malnutrition, hormone disorders, disease states and the like. Blood tests can be used to conduct tests.

\r\n\r\n

\r\nSub-items on hair loss

\r\n\r\n

\r\nTelogen effluvium
\r\nSince most hair is always in the anagen (growth) phase, the daily hair loss according to Telogen (hair loss) usually does not occur. This type of hair loss generally does not create bald spots on the head, but the hair becomes thinner.
\r\nThis often leads to hair loss in situations where there are potential triggers such as surgery, childbirth, fasting weight loss, drug use, hormonal changes, chronic illnesses, hypothyroidism and malnutrition (malnutrition), physiological or psychological stress. Surgical procedures that require anesthesia are particularly associated with telogen effluent. Anesthesia can lead to premature telogen (spillage) of some anagenic (growth) hair follicles, which blocks the rapid cell division required to maintain hair growth. Telogen can last for a few months and usually creates a delay between the triggering event and hair loss

\r\n\r\n

\r\nAlopecia areata (ringworm)
\r\nChronic disease, which is characterized by recurrent hair loss. It is known as ringworm among humans.

\r\n\r\n

Androgenetic alopecia
\r\nAlso known as bald male. This type of hair loss is more common in men than women. Increased androgen levels in the papillae can shorten the lineage (growth) until the follicle stops hair growth completely and gradually reduces the shaft diameter, length and pigmentation of the hair.
\r\nAndrogenetic alopecia is inherited. It is also associated with metabolic conditions such as insulin

\r\n\r\n

Iron
\r\nThe main function of the iron mineral in the body is to participate in the construction of red blood cells, which are responsible for the transport of oxygen from the lungs to all other organs. With iron deficiency, the amount of hemoglobin in the blood, which is defined as iron deficiency anemia, is reduced.
\r\nIron deficiency; Malabsorption (malabsorption), gastrointestinal bleeding, menopause in women, pregnancy, menstruation.
\r\nMalobsortive surgeries can lead to reduced iron absorption and inadequate iron absorption due to reduced nutrient absorption due to restrictive operations (gastric sleeves, stomach folds, etc.).
\r\nIron deficiency anemia can mean tachycardia (rhythm disturbance), tiredness, shortness of breath. Low iron levels, even if they do not occur with anemia, can lead to keratin disorder in the hair structure, which may be associated with telogen defluvium, alopecia areata and androgenic alopecia. However, there are different dates in the literature in this edition and there is no consensus on the role of iron minerals in hair loss.

\r\n\r\n

Biotin
\r\nBiotin, B-complex vitamins, also known as B7 and H vitamins. Carbohydrates have the task of supporting the gluco-transforming, fat and protein metabolism, skin, hair, nail growth. B7, a water-soluble vitamin, is not stored in the body, but is obtained from a variety of foods and can be produced by the intestinal flora. Biotin deficiency is extremely rare. Antiepileptics, malabsorption conditions such as Crohn's disease and long-term parenteral nutrition (intravenous nutrition) can cause a lack of biotin. Studies have shown that post-bariatric (post-obesity) hair loss has been reduced in individuals receiving biotin supplementation. However, there was no association between bariatric surgery and biotin deficiency.

\r\n\r\n

Protein
\r\nProteins and basic building blocks of the body are amino acids. While some amino acids can be synthesized in our body, some amino acids (essential) have to be ingested through food. Proteins that the body absorbs through food are broken down by the digestive tract and made available to the skin with the necessary ammonia products.
\r\nThe keratin in the hair structure is protein, and protein malnutrition (especially L-lysine) can affect hair growth. After insufficient protein intake, hair loss is associated with Telogen Effluvium. In addition, hair loss, loss of elasticity, thinning, discoloration, discoloration from brown hair to yellow hair, red and yellow streaks in dark hair can occur.

\r\n\r\n

Essential fatty acids
\r\nLinoleic acid from the omega-6 group and α-linoleic acid from the omega-3 group are important for human health. These fatty acids cannot be synthesized in the human body, and for this reason nutrients such as linseed, leafy greens, seafood, etc. must be obtained.
\r\nThe regulation of gastrointestinal operations in fat metabolism (gastric bypass, ileum interposition) can show a lack of essential fatty acids. Skin lesions, hair pigmentation, scaling, eyebrow failure, etc. There is an indication of a lack of fatty acids.

\r\n\r\n

Copper
\r\nCopper is one of the trace elements in our bodies. The brain is involved in various metabolic processes in the central nervous system and is necessary for the production of the immune system, connective tissue and melanin production. Copper deficiency is rarely observed and some malocclusive operations have been described as defective.
\r\nCopper deficiency can cause neurological problems such as gait abnormalities, loss of perception, visual disturbances. Copper plays an important role in iron absorption, which can lead to hair loss associated with copper iron deficiency.

\r\n\r\n

Other nutrients
\r\nNiacin (vitamin B3), vitamin B12, selenium, vitamin A, vitamin C and some other micronutrients are deficiencies that are associated with reduced nutrient intake after bariatric surgery.
\r\nThese nutrients can be associated with hair loss, hair growth and hair growth.
\r\nControl of hair loss after bariatric surgery
\r\nHair loss after bariatric surgery is usually temporary, but it may be necessary to take measures to reduce hair loss. In most cases, the hair grows back within a few months after the rapid weight loss (first 9 months). If hair loss continues for 6 months or more, other causes of hair loss are examined and attempts are made to control the loss through treatments.

\r\n\r\n

Dietary supplements are not a solution
\r\nGiven the specific nutritional deficiency associated with hair loss, these nutrients are effective in regrowth, but there has been no evidence to prevent or treat hair loss after bariatric surgery. Many scientific studies on hair loss show that supplements with iron, zinc or biotin, as well as zinc shampoos, which supplement a lack of nutrients, trace elements, topical preparations (body care regimen and the like) did not prevent hair loss and were not successful.

\r\n\r\n

Taking too many water-soluble vitamins, such as biotin, has no advantage in terms of hair loss, but is also not objectionable. However, excessive absorption of elements such as iron, zinc or copper can have toxic effects. Adequate nutrition with an appropriate bariatric diet and additional food under the control of doctors and specialists reduces the risk of hair loss and is more positive in relation to your general health.

\r\n\r\n

Should I use Minoxidil?
\r\nRocaine, Regain or Loniten can be used for hair growth. In the 1970s, the market for minoxidil for the treatment of high blood pressure was withdrawn due to the strong promotion of hair growth. Minoxidilin is believed to stimulate hair growth by prolonging the anagen cycle and increasing blood flow to the hair follicles. Minoxidil can be used for the topical treatment of androgenic alopecia (male pattern baldness). Stopping the application will cause hair loss to start again. Some people have reported hair loss increased after taking minoxidil. The use of minoxidil in the treatment of Telogen Effluvium shows that hair growth is present, but this has not been proven.

\r\n\r\n

\r\nFinasteride
\r\nDrug used in men with androgenic alopecia (male pattern baldness) taken orally. It is considered equivalent to topical minoxidil. It can cause difficulties such as sexual restraint, erection difficulties, and an increase in male breast cancer.

\r\n\r\n

\r\nHair implantation
\r\nIn some cases, permanent hair loss, hair transplantation, or hair removal may require intervention. After bariatric surgery, it is necessary to stabilize the hair growth time to think about hair extractions. For this reason, it is recommended to wait at least two years after the operation.

\r\n\r\n

Biochemiker- Bariatrischer Lebenstrainer
\r\nAlper Habip
\r\n

\r\n\r\n

In the preparation of this article, the scientific foundations have been examined and used from the following sources.

\r\n\r\n

\r\n1. Gordana Bosnic , Critical Care Nursing Clinics of North America, Volume 26, Issue 2, Pages 255-262 , June 2014,
\r\n
\r\n2. Amanda Velazquez , Caroline M. Apovian, Nawfal W. Istfan , The American Journal of Medicine, Volume 130, Issue 7, Pages e293-e294, July 2017,
\r\n
\r\n3. Dimitris Papamargaritis, Erlend T. Aasheim, Barry Sampson, Carel W. le Roux, Journal of Trace Elements in Medicine and Biology, Volume 31, Pages 167-172 July 2015,
\r\n
\r\n4. Meyler's Side Effects of Drugs (Sixteenth Edition), Minoxidil, Pages 1053-1056, 2016,

\r\n","createDate":"2020-01-09T11:47:00","status":1,"picture":"https://cdn.clinicways.com/news/700bd865-8e40-415c-8740-114f3ad678d0/Main.JPEG","guid":"700bd865-8e40-415c-8740-114f3ad678d0","newsType":1,"seoUrl":"hair-loss-after-sleeve-gastrektomy","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Hair loss, which usually occurs between the 3rd and 9th month after surgery, is in fact not a health problem and is temporary. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":104,"title":"13 Ways to Keep Your Mind Sharp ","newsContent":"

\r\n\r\n

Do a puzzle or two.

\r\n\r\n

Trying to keep your brain active? Play games! A 2019 study published in the International Journal of Geriatric Psychiatry found that adults over 50 who do word and number puzzles have the equivalent brain function of someone up to 10 years younger than they actually are.

\r\n\r\n

"We've found that the more regularly people engage with puzzles, such as crosswords and Sudoku, the sharper their performance is across a range of tasks assessing memory, attention, and reasoning," lead researcher Dr. Anne

\r\n\r\n

Corbett, of the University of Exeter Medical School, said in a press release. "The improvements are particularly clear in the speed and accuracy of their performance."

\r\n\r\n

Get your olive oil fix.

\r\n\r\n

What you eat feeds your brain, too. And if you want to keep your mind sharp, you should consider the Mediterranean diet. One 2017 study published in Journal of the American Geriatrics Society showed that older people who ate a Mediterranean-style diet—which includes a healthy amount of olive oil—had a 35 percent lower risk of scoring poorly on cognitive tests than those with other diets. Even those with a moderate Mediterranean-style diet had a 15 percent lower risk.

\r\n\r\n

Have more fish.

\r\n\r\n

Eating boiled or baked (not fried!) fish can be the key to improving your brain function, according to a 2008 study published in the journal Neurology. In the study, people who consumed omega-3-rich fish three times or more per week had a nearly 26 percent lower risk of having silent brain lesions that are often the cause of memory loss. Just one serving per week resulted in a 13 percent reduced risk.

\r\n\r\n

Eat more salad.

\r\n\r\n

Fresh salads are the way to go when it comes to boosting your brain power. According to Gary Small, director of UCLA's Longevity Center and author of The Alzheimer's Prevention Program, the antioxidants in fruits and vegetables protect your brain from "wear and tear" and "the stress of aging."

\r\n\r\n

It's recommended that folks over 30 eat two to three cups of vegetables and one to two cups of fruit each day, per the United States Department of Agriculture.

\r\n\r\n

Get in more cardio.

\r\n\r\n

Running isn't only good for your heart and waistline, it benefits your brain, too. Small says just 15 to 20 minutes of cardio a day can actually lower someone's risk of Alzheimer's. That's because increased blood flow helps brain cells communicate better, he says.

\r\n\r\n

And there's research to prove it: A 2018 study published in Neurology showed the women who had high physical fitness during their midlife were 88 percent less likely to develop dementia. And those who did develop the disease saw their symptoms start an average of 11 years later than women who were less fit.

\r\n\r\n

Monitor your blood pressure.

\r\n\r\n

The higher your blood pressure is when you're younger, the more likely you are to damage and lose brain matter in key areas as you age, according to one 2012 study published in The Lancet. Chronically high blood pressure, which is anything above 120/80, deprives your brain of blood and nutrients over time.

\r\n\r\n

"The message here is really clear: People can influence their late-life brain health by knowing and treating their blood pressure at a young age, when you wouldn't necessarily be thinking about it," study author Charles DeCarli said in a statement.

\r\n\r\n

Watch your weight.

\r\n\r\n

Those who pack on the most abdominal fat by their 40s are the most likely to develop dementia later on, according to a 2008 study published in Neurology. According to the researchers, that's because fat cells increase inflammation throughout the body and brain.

\r\n\r\n

"It is well known that being overweight in midlife and beyond increases risk factors for disease," study author Rachel Whitmer, PhD, a research scientist at the Kaiser Permanente Division of Research in Oakland, California, said in a statement. "However, where one carries the weight–especially in midlife—appears to be an important predictor for dementia risk."

\r\n\r\n

Drink more wine.

\r\n\r\n

Want to boost your brain? Drink a glass of red wine every day—and make it merlot! This type of wine has the most resveratrol, an antioxidant that protects neurons from damage, says William J. Tippett, director of the University of Northern British Columbia Brain Research Unit. And good news: dark chocolate has resveratrol, too. Now you can feel far less guilty about your favorite indulgences!

\r\n\r\n

Control your stress levels.

\r\n\r\n

As Tippett notes, stress increases the body's production of the hormone cortisol. And, unfortunately, that increase can affect your memory, learning, and the production of neurotransmitters. In fact, a 2018 study published in Neurology found that adults in their 40s and 50s with higher levels of cortisol performed worse on memory and other cognitive tasks than their peers with average cortisol levels.

\r\n\r\n

Practice mindfulness.

\r\n\r\n

Being present is the perfect way to set your brain up for a brighter future. A 2010 study published in the journal Psychiatry Research had participants take an eight-week mindfulness meditation program. The results? Significant and measurable increases of gray matter density in the hippocampus, which is the part of the brain associated with memory and learning. Participants also showed a decrease of gray matter density in the amygdala, which is linked to anxiety and stress. Win-win!

\r\n\r\n

Do more things you're not good at.

\r\n\r\n

Can't sing? Keep trying. A mess at chess? Challenge yourself to another game. Turns out, trying new things will help grow new brain connections. "As we become older, we tend to do things we're already good at," says Tippett. "But you have to step out of your comfort zone to keep your cognitive edge."

\r\n\r\n

Protect your head.

\r\n\r\n

According to the Centers for Disease Control and Prevention (CDC), approximately 1.5 million Americans face a traumatic brain injury (TBI) each year. And while 75 percent of those brain injuries are mild TBIs, just one concussion can lead to lasting brain damage, according to a 2013 study published in the journal Radiology. So, for the sake of your brain, put on that helmet when you're playing a contact sport, riding a bike or skateboard, or skiing or snowboarding.

\r\n\r\n

Ways to Keep Your Mind Sharp

\r\n\r\n

As our age increases, unfortunately, our brain power decreases. But the good news is, there are plenty of ways you can keep your mind sharp as the years march on. In fact, a 2018 study published in the Journal of the American Geriatrics Society found that even older patients in the early stages of memory loss were able to increase their memory test scores by up to 40 percent through cognitive training. What exactly does that entail? Well, if you're looking to up your brain game, try some of these science-backed ways to keep your mind sharp. It turns out, it doesn't take much time to keep your brain young!

\r\n\r\n

\r\n","createDate":"2019-12-26T21:28:00","status":1,"picture":"https://cdn.clinicways.com/news/85cfc64d-9c0a-4e9e-9e02-7f2ba4fd21a1/Main.JPEG","guid":"85cfc64d-9c0a-4e9e-9e02-7f2ba4fd21a1","newsType":1,"seoUrl":"13-ways-to-keep-your-mind-sharp","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"As our age increases, unfortunately, our brain power decreases. But the good news is, there are plenty of ways you can keep your mind sharp as the years march on.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://bestlifeonline.com","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":101,"title":"3 Things Your Finger Length Could Say About Your Personality ","newsContent":"

Although our appearance comes from genetics, some parts of our body can reveal interesting information about our personalities. Studies have shown that the length the ring finger depends on the levels of testosterone, the male hormone, which you were exposed to in the womb and it can have a direct impact on the formation of the personality.

\r\n\r\n

To check this test, look at your left hand and compare your index and ring fingers and then find which hand image below looks like yours.

\r\n\r\n

The index finger is shorter than the ring finger.

\r\n\r\n

People with the ring finger longer than the index finger are often very attractive, charismatic, and charming. They have excellent communication skills and know how to get attention and keep it. They are risk-takers and it often pays off. If something doesn’t quite go to the plan, they don’t get discouraged, because there is always another way.

\r\n\r\n

This is why they normally excel in anything they choose to do. They are high achievers and always set high targets. Some might call them too aggressive, but they don’t mean be, they just can’t help it. We can only blame that high level of testosterone for it.

\r\n\r\n

The index finger is longer than the ring finger.

\r\n\r\n

People with the ring finger slightly shorter than the index finger are very confident and quite self-sufficient. They are good leaders and are natural at leading the pack. They are calm and even-tempered, nothing can make them lose face.

\r\n\r\n

They are normally not people who take the first step, whether it is a new business or a relationship. However, when they do, they stay with it and they like to be in charge. They have a very analytical mind and always think about all possible outcomes before making any decisions. They don’t like being spontaneous.

\r\n\r\n

The index and ring fingers are the same length.

\r\n\r\n

People with the index and ring fingers of about the same length, are very caring, well-balanced, peaceful, and down to earth. They have very gentle personalities and try to avoid any conflict situations and risks. Uncertainty makes them feel very uncomfortable.

\r\n\r\n

They are very good friends and always ready to help others. They are very loyal and faithful, whether it is at work, in a friendship, or in a relationship, you can always rely on them. They are very positive and see something good in every situation.

\r\n","createDate":"2019-12-20T06:59:00","status":1,"picture":"https://cdn.clinicways.com/news/a494a2b8-3163-44fe-8526-1a248ac30945/Main.JPEG","guid":"a494a2b8-3163-44fe-8526-1a248ac30945","newsType":1,"seoUrl":"3-things-your-finger-length-could-say-about-your-personality","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Although our appearance comes from genetics, some parts of our body can reveal interesting information about our personalities.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://brightside.me/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":98,"title":"Brushing your teeth could benefit your heart","newsContent":"

Regular brushing of teeth not only helps to avoid tooth decay and periodontitis. The extent to which oral hygiene can affect health is still often underestimated. A South Korean study now shows a possible further connection. The results, which have been published in the journal "European Journal of Preventive Cardiology", show that people who brush their teeth at least three times a day have a lower risk of cardiac arrhythmia and heart failure.

\r\n\r\n

Hardly any other place in the human body contains more bacteria than in the oral cavity. If tooth cleaning is neglected, it will no longer be kept in check. As a result, inflammation can occur, which initially affects teeth and gums and then migrates into the body via nerve tracts and blood vessels.

\r\n\r\n

Reducing bacteria in the mouth avoids diseases
\r\nThe connection between dental hygiene and a number of diseases has long been known - for example in pneumonia and heart inflammation, erectile dysfunction, heart attacks and strokes. The study by the South Korean Ewha Women's University has shown another possible connection.

\r\n\r\n

The team led by Tae-Jin Song used the database of the National Health Insurance System for the analysis and selected 161,286 participants between the ages of 40 and 79 whose medical history did not include any heart diseases. During an investigation, their data on height, weight, laboratory values, diseases, lifestyle, oral health and oral hygiene behavior were recorded. The investigation was repeated an average of a decade later. At the time, 4911 of the participants (three percent) had developed atrial fibrillation - a cardiac arrhythmia - and 7971 (4.9 percent) had heart failure.

\r\n\r\n

It was striking that those who brushed their teeth three or more times a day had a ten percent lower risk of atrial fibrillation and a twelve percent lower risk of heart failure than those with poorer oral hygiene. Recurring professional tooth cleaning also had a positive effect. These results were independent of factors such as age, gender, socioeconomic status, regular exercise, alcohol consumption, body mass index and other factors such as high blood pressure.

\r\n\r\n

\r\n","createDate":"2019-12-19T14:06:00","status":1,"picture":"https://cdn.clinicways.com/news/fef7feca-bee6-47c7-8e1f-d01a963e7a62/Main.JPEG","guid":"fef7feca-bee6-47c7-8e1f-d01a963e7a62","newsType":1,"seoUrl":"brushing-your-teeth-could-benefit-your-heart","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"People who brush their teeth a lot may have a lower risk of arrhythmia and heart failure, according to a Korean study.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://www.faz.net/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":95,"title":"8 Signs It’s Not Your Body That’s Exhausted — It’s Your Soul ","newsContent":"

If you feel drained and weak most of the time we are here to tell you that you are not alone. One out of 5 people feel tired at any given moment and, unfortunately, exhaustion is becoming the norm. The rhythm of the modern world involves constant work, stress, tension, and a lack of sleep and proper exercise. And all of this affects the state of the soul. It hurts and needs help.

\r\n\r\n

1. Being tired after a full night’s rest

\r\n\r\n

The fact that it’s difficult for you to wake up and get out of bed in the morning, even if you’ve slept the proper number of hours, can be the first sign. You have recovered physically, but it’s difficult to restore your soul with sleep. As a result, chronic fatigue appears and you spend the whole day fighting with yourself every time you need to do something.

\r\n\r\n

2. Daydreaming and escaping reality

\r\n\r\n

If you feel like you want to escape reality and you dream of a different life, your soul is giving you signs of exhaustion. You often think about the past and are afraid of the future. The main thing is that you don’t like the present moment and you try to distract yourself from it by any possible means. But escapism can bring you harm since you still have to go back to your daily duties and your dissatisfaction with life increases due to the mismatch of reality and your dreams.

\r\n\r\n

3. Indifference and lack of aspiration

\r\n\r\n

Considering that you constantly feel tired, you may experience a lack of desire to do things, show indifference to everything that happens around you, and even lose interest in what you previously liked. You might see no point in what you do and become apathetic to the results of your actions. These conditions create additional tension, since you still have to fulfill your duties even if you have no energy and aspirations.

\r\n\r\n

4. Abrupt changes in emotions

\r\n\r\n

Dissatisfaction, fatigue, and indifference can affect your emotions. How often do you become angry, take offense at something small, or start crying or laughing unexpectedly and for no reason? If mood changes like this happen regularly, this may be a sign of an exhausted soul. Life becomes harder with these emotional swings. And it forces you to look for conflict more than trying to achieve peace and understanding with others.

\r\n\r\n

5. Pretending to feel well

\r\n\r\n

Don’t think that hiding your pain and pretending to be ok is a good way to solve the problem. If you do this, you lie to yourself and others about your real feelings, while everything inside you is breaking down. You try your best to smile and spend extra energy trying to create the illusion of joy when your soul is crying. But it’s tired and has no strength to pretend that everything is fine.

\r\n\r\n

6. Feeling lonely

\r\n\r\n

If you direct all your anger and offense on the people who surround you, your relationships can become tense. When you pretend to feel well, nobody knows the real state of things. This can all make you feel lonely and left alone with your problem. You start to think that nobody understands you, nobody accepts you, and that no one can help. So you try to handle everything alone, struggling with your condition day after day.

\r\n\r\n

7. A desire to hide from others

\r\n\r\n

If you have a desire to hide from people that surround you, this is a telltale sign of a tired soul. You may want to sit in the corner, to shield yourself from others, or even become inconspicuous. But since you can’t lock yourself in your home and stop interacting with people, you become oppressed by unwanted communication. You still need to keep up your day-to-day conversations and stay close to other people, even if you want to be left alone.

\r\n\r\n

8. Negative thinking

\r\n\r\n

Do you notice pleasant little things, remember funny incidents, and try to create happy moments? If you’ve gotten used to concentrating on negative and bad experiences your soul may suffer from exhaustion. You don’t charge yourself with positive energy. On the contrary, you waste it while constantly re-living or expecting the unpleasant moments to happen. This affects your mood and creates a feeling of unhappiness.

\r\n\r\n

\r\n","createDate":"2019-12-15T14:02:00","status":1,"picture":"https://cdn.clinicways.com/news/37eccf60-9be8-4136-8f62-f0a9f8434adf/Main.JPEG","guid":"37eccf60-9be8-4136-8f62-f0a9f8434adf","newsType":1,"seoUrl":"8-signs-it-s-not-your-body-that-s-exhausted-it-s-your-soul","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"If you feel drained and weak most of the time we are here to tell you that you are not alone. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://brightside.me/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":92,"title":"Things You Need to Stop Shaming Yourself for in Your Life ","newsContent":"

Sometimes we blame ourselves for the way we live our lives because they are not as perfect as we want them to be. When we talk to our friends or scroll through social media, and come to the conclusion that our lives pale in comparison. We make ourselves feel guilty about the things that we should be unapologetic about. It’s now time to embrace ourselves and stop shaming ourselves for these things.

\r\n\r\n

1. Your career choices

\r\n\r\n

The more unusual and less-paying a job is, the more you tend to shame yourself for your career choices. You doubt yourself more if you have the qualifications for more stable jobs with better salaries, but chose a different career path. The pressure is even greater when your friends go on to climb the corporate ladder. But if you are happy with your job, you should take pride with what you do, no matter what.

\r\n\r\n

2. Your disabilities or lack of ability

\r\n\r\n

You may experience being slighted due to your disabilities or lack of ability in something, but you should not shame yourself for it. Everyone has their own strengths and weaknesses, so if you are not good at something that doesn’t make you a loser. Having disabilities or a lack of abilities simply means that your strengths lie elsewhere.

\r\n\r\n

3. Wanting some “me” time

\r\n\r\n

In an extroverted world, sometimes it is hard to excuse yourself so that you can have time to yourself. If you are a mother, you might feel even guiltier about hiding in the pantry before your kids come and find you. But the truth is, everyone deserves to have time to be on their own and pamper themselves without worrying about others for a while. So take 5 and don’t feel guilty about it.

\r\n\r\n

4. Friends and partners you choose

\r\n\r\n

You may have a partner or friends in your life that other people think are not good enough for you. But if they treat you well, it should not matter if they are considered “not cool” or not good enough. You should be glad that there are people like them in the world who care about you.

\r\n\r\n

5. Where you came from

\r\n\r\n

If you are ashamed about your past, it is unlikely that you will be able to appreciate the present and look forward to the future. Accepting your past as the thing that has shaped you is one of the ways to start loving yourself. If you came from a bad place, let it be a reminder that you are better off now or that you can be better off.

\r\n\r\n

6. The food you eat

\r\n\r\n

Health-conscious friends may try to guilt-trip you whenever you enjoy something sinfully delicious. But you should not shame yourself for indulging in food as long as you take care of your health. Eating is one of the greatest pleasures in life and if you can afford it, you should enjoy it.

\r\n\r\n

7. Your relationship status

\r\n\r\n

Maybe you prefer being single or feel you are better off divorcing your partner. Even if people disagree with you, you should not shame yourself for not being with someone. Sure, being romanced or getting married may seem great, but if you feel you need to be single, you should not feel guilty about it.

\r\n\r\n

8. Being different

\r\n\r\n

It is already difficult to be part of a minority, so it doesn’t help if you also make yourself feel bad about being different. Instead of trying to fit in and be part of the majority, you should embrace your uniqueness and make a good use of it.

\r\n\r\n

9. The things that you can and cannot afford

\r\n\r\n

In this materialistic world, it is not unusual to feel ashamed if you cannot afford branded and trendy things. However, you should remember that labels should not define you. Live within your means and be happy with what you have.

\r\n\r\n

10. Your body weight, size, or shape

\r\n\r\n

Certain body weights, sizes, and body shapes may be preferable in the media, but that is not a good reason to shame yourself for your body. Health should be more important than the way your body looks so if you have that down, you should never feel ashamed of your body. Look into the mirror and tell yourself that you are beautiful because that is the truth.

\r\n\r\n

11. The interests you have

\r\n\r\n

Even hobbies have different statuses in the eyes of society. But if you truly enjoy reading, being part of a glee club, collecting figurines, knitting, or anything at all, you should take pride in that. Provided that it’s not harmful to anyone, you should be free to have an interest in anything.

\r\n\r\n

12. Being emotional

\r\n\r\n

Being an adult sometimes means that you are expected to not show too much emotion. Even so, you are not a robot and should be allowed to express your emotions. So let the tears roll when your heart breaks or even when you are watching a movie. There’s no need to shame yourself when you’re expressing yourself and are unable to reel in your feelings when things truly affect you.

\r\n\r\n

13. The way you dress

\r\n\r\n

Perhaps society has certain ideas about how you should dress, but you should not join those who shame you because of the way you dress. You should be proud of whatever you are comfortable wearing. Your clothes should be your decision, so wear them with confidence.

\r\n\r\n

14. Having miscarriages or being unable to conceive

\r\n\r\n

This is perhaps not talked about enough. Miscarriages and the inability to conceive are not very uncommon, but women tend to blame and shame themselves for them. The truth is, usually these are not your fault. You should keep reminding yourself that you are not the problem.

\r\n\r\n

\r\n","createDate":"2019-12-13T17:05:00","status":1,"picture":"https://cdn.clinicways.com/news/60e22601-ffb8-4da7-9aa8-0d2cef4e124d/Main.JPEG","guid":"60e22601-ffb8-4da7-9aa8-0d2cef4e124d","newsType":1,"seoUrl":"things-you-need-to-stop-shaming-yourself-for-in-your-life","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Sometimes we blame ourselves for the way we live our lives because they are not as perfect as we want them to be. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://brightside.me/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":89,"title":"Why the Strongest Women Often Feel So Broken Inside ","newsContent":"

When we meet a strong woman, we may feel drawn in by her confidence. It seems like she has it all: a successful job, a lovely family, good health, and even the time to help those in need. But behind that bright smile, many of these women feel broken to a point where it starts affecting their health.

\r\n\r\n

1. She only relies on herself.

\r\n\r\n

A strong woman likes being independent; she doesn’t need anybody’s help. Such a woman tends to be confident and rely on herself. Research shows it may even be part of her identity that makes her proud. The problem is, she only relies on herself and doesn’t understand that all people need help sometimes — even her.

\r\n\r\n

It may be because she doesn’t want to be a bother, or because she sees asking for help as a weakness.

\r\n\r\n

However, as social beings, humans need help every once in a while. Psychologists agree that we need them and their support for our well-being. Asking for help when you need it is not only healthy, but it’s also generous because you’re allowing someone else to ask for help back when they need it.

\r\n\r\n

2. Everyone trusts her with their problems, and she carries the weight on her shoulders.

\r\n\r\n

It’s not a surprise that her family and friends confide in her since people consider her to be trustworthy. Research shows that this is because mentally strong people also have a high sense of responsibility which people perceive as integrity and wisdom.

\r\n\r\n

But the strong woman doesn’t share her family or friends’ struggles with anyone, nor does she gossip about them. She carries all the suffering that is bestowed upon her. And if the problem affects her directly, she might even take the lead to solve it or face it, whether it’s a money issue or an illness in the family.

\r\n\r\n

3. But she doesn’t share her problems with anyone else, locking that burden deep inside of her.

\r\n\r\n

The strong woman takes on everyone else’s burdens but doesn’t share her own. This has been proven to make people feel extremely lonely, and it may also lead to depression. Sometimes she doesn’t want to let it all out because it’s a behavior that doesn’t match her constructed identity of a strong person.

\r\n\r\n

But in doing so, she makes the mistake of holding in her problems and those of her relatives and friends as well. Research shows we need interaction with other people to be able to increase our happiness and cope with the harder things in life. Not sharing her issues isn’t a good way to achieve a healthy mental state.

\r\n\r\n

4. She cares for others but forgets she needs care too (and so does everyone else).

\r\n\r\n

The strong woman cares for her family and relatives, she even carries some of their emotional baggage to ease their burdens. But in doing so, sometimes she forgets she needs care — and others forget too. She looks so well put together that no one takes the time to think she might be having a hard time.

\r\n\r\n

After receiving help, some of her friends may ’’close the case’’ and whether they’re forgetful and go back to their schedules or simply like to move on with their independent lifestyle, they forget to ask her if she’s okay. And that perceived lack of interest hurts her.

\r\n\r\n

5. It also affects her physically — when she refuses to show her vulnerable side, she damages her cardiovascular health.

\r\n\r\n

Sometimes she needs to portray an image of security and strength through rough times in front of vulnerable people like her children or seniors. However, if she does this too regularly, she ends up hurting her heart. A study revealed that frequently suppressing emotions puts an extra burden on the heart and increases the chance of developing cardiovascular disease and other conditions.

\r\n\r\n

It turns out, she doesn’t only feel damaged inside, she may actually be damaged inside.

\r\n\r\n

6. Her strength may be the result of a tragic story she hasn’t told you yet.

\r\n\r\n

The sentiment, “What doesn’t kill you makes you stronger,” is exactly what this research has proven. A woman can become resilient after tragic events and become tougher — she may even rise up after a dramatic incident. A strong woman may be strong because she learned and grew after an unfortunate event, but that doesn’t mean she doesn’t get sad when she remembers it. It’s still in her mind in the shape of a psychological scar, and every once in a while, it might make her feel a bit broken.

\r\n\r\n

7. And some days, they break down and feel they’re not strong enough to take on a task.

\r\n\r\n

She puts on a mask at work or at home but when she’s alone, it’s time for a reality check and her insecurities pay a visit. Friends, relatives, and coworkers regard her as a strong woman and expect a lot from her. However, research reveals the level of self-control she imposes on herself along with everyone else’s high expectations of her can damage her psychologically. When thinking about her hidden faults and suppressed emotions, she breaks down.

\r\n\r\n

She believes she’s inadequate and not up to the task. It’s this mismatch of emotions that leaves her exhausted.

\r\n","createDate":"2019-12-09T20:28:00","status":1,"picture":"https://cdn.clinicways.com/news/3a2a8338-cfb7-4867-aa28-c024f4c64e77/Main.JPEG","guid":"3a2a8338-cfb7-4867-aa28-c024f4c64e77","newsType":1,"seoUrl":"why-the-strongest-women-often-feel-so-broken-inside","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"When we meet a strong woman, we may feel drawn in by her confidence","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://brightside.me/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":86,"title":"8 Ways to Save Yourself From Someone Who Talks Too Much ","newsContent":"

An “entertaining” story about their granny, their cat, or just their walk to work: Some people just need to express their thoughts and can’t stop. Of course, it’s important to be polite and to not interrupt people, but this might get to a point where they start wasting your time on their mindless things. So, the most important thing to do here is to “fight” for yourself and know how to escape these people.

\r\n\r\n

1. Listening politely

\r\n\r\n

The first step is to listen with patience. It’s important to figure out what this person is trying to tell you. Maybe, there is an important thought that they are trying to express or a feeling they need to show. Or maybe, they want to be admired. If it’s something really important, the speech shouldn’t take too long.

\r\n\r\n

2. Asking often what the main point is

\r\n\r\n

It can happen that the person just keeps deviating from the topic, talking more about the irrelevant things and details. In this case, it will be good to remind them what the main point of your conversation is. You can also question them about it, so they will have to return from heaven to earth. After all, it’s good to show people that they need to respect your time.

\r\n\r\n

3. Asking if you can interrupt them

\r\n\r\n

If after all your previous attempts to finish the conversation, they still don’t stop, then it might be high time to be more assertive. You can ask them politely, but confidently, if they mind if you interrupt them. Some of them might realize that the conversation has dragged on for too long and some of them might ask you to let them finish their thought.

\r\n\r\n

Here it’s fine to let them finish, since you don’t really have a choice. But as soon as you feel that they are going to move on to another topic, this is your chance to interrupt them again.

\r\n\r\n

4. Turning the tables

\r\n\r\n

After interrupting them, you can “turn the tables.” Instead of stopping the conversation completely, you can add a comment about them. Adding a similar mindless story about yourself, your dog, or your friend might actually have a positive effect. You will make them experience how you feel and they might stop talking.

\r\n\r\n

5. Telling them you have no time

\r\n\r\n

Sometimes, people just can’t take a hint. It won’t do any harm to push them a bit more. By telling them you don’t have time anymore to listen to them, you will show that you are very busy at this moment and can’t be disturbed anymore. You can add that as soon as you are done with your work, you can finish the conversation. And if it happens that they actually come back to finish their talk, you can always say, “Not now, I’m still busy.”

\r\n\r\n

6. Agreeing on a specific talk time

\r\n\r\n

Reminding them that you have a tight schedule can also do the trick. In some cases, you can even complain about the lack of time and the amount of things that need to be done. If you see that they really want to finish their talk, then propose a specific time when you can do it again. While doing this, you can emphasize one more time that it is not that easy for you to choose it, as you have a lot of work to get done.

\r\n\r\n

7. Showing your dislike

\r\n\r\n

It can happen that they don’t care about anything and just can’t stop talking. They just want to tell their life story to anyone who they meet on their path. If none of your tricks to stop their speech worked, then you might just show that you dislike the situation. Your body language together with your annoyed facial expression will show them that their speech is not welcome anymore.

\r\n\r\n

8. Just leaving

\r\n\r\n

It’s rude, but effective. If it gets to the point where they are stopping you from doing your tasks and ignoring your body language, then this can be a sign for you. Yes, it’s time to just leave. After all, enough is enough, you have your own life and things you need to concentrate on.

\r\n","createDate":"2019-12-05T06:57:00","status":1,"picture":"https://cdn.clinicways.com/news/c07a78b1-4bad-4a63-90fb-debd7fa815ef/Main.JPEG","guid":"c07a78b1-4bad-4a63-90fb-debd7fa815ef","newsType":1,"seoUrl":"8-ways-to-save-yourself-from-someone-who-talks-too-much","author":null,"categoryid":8,"mainCategoryid":0,"categoryName":"Göz Cerrahisi","shortDescription":"Some people just need to express their thoughts and can’t stop","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://brightside.me/","categoryicon":"category-icon-other","categorycolor":"10c45c","language":"En","newsList":[],"doctors":[]},{"newsid":83,"title":"5 Psychological Techniques That Can Help You Forget What You Want ","newsContent":"

We’re not always very good at remembering things since even a walk through a doorway makes us forget what we came into the room to do. But somehow, some events we’d like to forget are forever stuck in our minds and it’s impossible to get rid of them. This is what makes our doorway memory loss even more unfair.

\r\n\r\n

Tip 1: Repeatedly stop yourself from thinking about it.

\r\n\r\n

If you want to remember your mom’s phone number, you’ll probably repeat it over and over again to make it stick in your memory. The technique to forget things works exactly vice versa: every time the memory comes to your mind, throw it away. You can also force yourself to think about something else in order not to come back to the memory you don’t want to remember. If you do this often enough, the memory will probably just get lost one day.

\r\n\r\n

Tip 2: Change the context.

\r\n\r\n

While thinking about your bad memory, you probably can recall many details like where it happened, how old you were, what you were wearing, or who you were with — basically, the context of the situation. Researchers have discovered that any memory is linked to the context of the experience, and the context helps us to remember it. Therefore, if you want to forget it, the context should be changed.

\r\n\r\n

Try to add some new controversial details that didn’t actually happen and start to think about the situation in different conditions. In the end, you’ll confuse your mind so much that it’ll push the memory out of your head.

\r\n\r\n

Tip 3: Make a stronger memory.

\r\n\r\n

This trick will only work if you do it right after experiencing something that you want to forget. After something you wouldn’t want to remember happened, you should do something that you could remember about that time instead, and this one should be stronger.

\r\n\r\n

For example, if you had an awkward conversation with your ex-friend, you could go and buy something you’ve been wanting for a long time, go to an amusement park, or just cuddle with a loved one since physical contact has a positive effect on mental health. And, of course, while distracting yourself, you shouldn’t keep thinking about what happened, otherwise you’ll just make it harder to forget by providing it with additional context.

\r\n\r\n

Tip 4: Distract your mind with a positive aspect.

\r\n\r\n

Every time the bad memory comes to your mind, try to recall something similar that was actually positive to replace a bad memory with a good one. For example, if you said something stupid to your friends and would like to forget this moment, recall some situations when you actually said something very smart or witty. Do it every time you recall the memory you want to forget and eventually, you’ll recall it for the very last time.

\r\n\r\n

Tip 5: Change the perspective.

\r\n\r\n

Sometimes we overthink and worry about something we shouldn’t. Our emotions are what don’t let us forget the memory, so the key here is to stop being emotional about the situation. Analyze your memory and try to think about it from a different perspective. Maybe nothing bad really happened or maybe it led to something good.

\r\n\r\n

If you can’t convince yourself and need someone else’s opinion, then tell someone about the memory. Perhaps the person’s reaction will assure you that you’ve been overthinking things and your emotionality will disappear, letting the memory fade away as well.

\r\n\r\n

\r\n","createDate":"2019-12-04T06:26:00","status":1,"picture":"https://cdn.clinicways.com/news/2c83f1fa-681f-452f-a0ce-c727d0e32236/Main.JPEG","guid":"2c83f1fa-681f-452f-a0ce-c727d0e32236","newsType":1,"seoUrl":"5-psychological-techniques-that-can-help-you-forget-what-you-want","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"We’re not always very good at remembering things since even a walk through a doorway makes us forget what we came into the room to do.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://brightside.me/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":80,"title":"What Weekend Anxiety Is and How to Overcome It ","newsContent":"

If you’ve ever had that feeling on Friday where you`re so worried about how you’ll spend your weekend, you`re not alone.

\r\n\r\n

There are actually so many people who have that fear of not spending their days off the right way, that there is a term for it

\r\n\r\n

— Weekend Anxiety Syndrome. Not doing the tons of cool things that other people are doing and posting about

\r\n\r\n

them on social media can

\r\n\r\n

make you feel like your weekends just aren`t good enough.

\r\n\r\n

What is Weekend Anxiety Syndrome?

\r\n\r\n

Weekend Anxiety Syndrome (WAS) is not an official medical term, but many people are affected by

\r\n\r\n

it and know exactly how it feels. After a whole week of hard work, you finally have 2 days to do whatever you want. You might have such high expectations about

\r\n\r\n

all the fun you can have that you're afraid your weekend won't be as eventful as you imagined.

\r\n\r\n

And that can put so much pressure on you and give you anxiety.

\r\n\r\n

Feeling pressured to do fun activities

\r\n\r\n

Sometimes you might feel like you go out not because you want to, but because everyone expects you to. Your friends probably have tons of plans for the weekend,

\r\n\r\n

and they all have to be super exciting and unusual so that you can discuss them with your colleagues

\r\n\r\n

on Monday. Or they don`t have any plans at all, and they`re ready to do whatever, whenever. Well,

\r\n\r\n

they`re your friends, so you might feel you have no other choice but to do the same.

\r\n\r\n

Even if you were planning to spend these 2 days doing nothing, just relaxing on your couch, cozily

\r\n\r\n

reading your favorite book or binge-watching a new TV show you haven`t had a chance to watch because you were so busy with work. All around you, there could be people who

\r\n\r\n

just can`t sit still and try to spend their weekends doing as many exciting things as they can.

\r\n\r\n

Especially when they post pictures on social media of all the amazing things they did. You see how

\r\n\r\n

they`ve met some new interesting people, how much fun they had at that stand-up club, and you can`t help but feel you`re missing out by just staying at home. And even if you do

\r\n\r\n

go out and do something, you might feel in the end that it just wasn`t fun enough, and your weekend

\r\n\r\n

seems wasted.

\r\n\r\n

But maybe sometimes it would be better to miss a party or a night out for the sake of having some much needed youtime. You can always go to another party next time, when you feel like it. And your friends

\r\n\r\n

are certainly not going anywhere, so you can ask for a raincheck. If they are really your friends, they

\r\n\r\n

will understand and give you time to relax on your own and make plans for another day.

\r\n\r\n

The pressure to have a fun weekend doesn`t necessarily have to come from other people. You yourself

\r\n\r\n

might be convinced that if your weekend isn`t full of all the exciting things you planned to do, or some

\r\n\r\n

cool spontaneous things, it can be called a failure.

\r\n\r\n

Modern life might be to blame.

\r\n\r\n

Dr. Luke Martin, a clinical psychologist, says it may be a side effect of modern life. We`re always so busy making plans, having meetings, and running errands, that when we actually

\r\n\r\n

have more free time we don`t know how to deal with it. This free time feels so precious to us that we

\r\n\r\n

get hung up on spending it the right way and getting the most out of it. We want everything we do during the weekend to be perfect. And that`s just not

\r\n\r\n

possible.

\r\n\r\n

Workaholics know the struggle.

\r\n\r\n

This kind of anxiety can be especially hard on workaholics. If you are one, you`re used to having a routine that works

\r\n\r\n

well from Monday to Friday,

\r\n\r\n

you know what to expect, and it can be easier to control your anxiety when day-by-day you do the same things and actually have things to do. However, when the weekend comes, there`s no routine,

\r\n\r\n

no more work to be done, and all the free time you have can be extremely overwhelming.

\r\n\r\n

Especially when you get a text from your friend out of the blue inviting you to go somewhere. It's exactly

\r\n\r\n

this spontaneity, not knowing what to expect, and not having a pre-planned schedule that can cause your anxiety levels to go up. There`s also another side to this, which is when

\r\n\r\n

workaholics decide to make their weekend as busy as possible with all kinds of activities, and end up having

\r\n\r\n

no rest at all.

\r\n\r\n

Recognize the symptoms.

\r\n\r\n

Here are some of the cues you can see in your behavior that can tell you that you might have Weekend

\r\n\r\n

Anxiety Syndrome:

\r\n\r\n

\r\n\t
Irritability
\r\n\t
\r\n\t
Frequent headaches
\r\n\t
\r\n\t
Feeling panicky
\r\n\t

\r\n\r\n

\r\n\t
Worrying too much
\r\n\t
\r\n\t
Being cranky
\r\n\t
\r\n\t
Upset stomach
\r\n\t
\r\n\t
Inability to relax around the house
\r\n\t

\r\n\r\n

What can you do to deal with WAS?

\r\n\r\n

If you`re used to having a set schedule Monday to Friday, and not having that on Saturday and Sunday is what makes you feel anxious, then plan ahead or even establish a weekend routine that you can do every weekend. Think of things that you find pleasant or relaxing. You can make plans to meet

\r\n\r\n

with your friends at a certain time and go see a movie or go to a café and chat. Or you can decide

\r\n\r\n

to spend some time alone watching TV at home or going for a jog in the park.

\r\n\r\n

Meditation, yoga, and spending time in nature can also help you deal with anxiety. In the end,

\r\n\r\n

every weekend can turn out a bit different, and that`s alright. One time you feel like you need to spend the

\r\n\r\n

whole 2 days relaxing

\r\n\r\n

at home, another time you might feel like going out and meeting with someone is what`s best

\r\n\r\n

for you. The most important thing is to not put pressure on yourself to do one thing or another

\r\n\r\n

and to make sure you enjoy your time

\r\n\r\n

off, no matter what it looks like.

\r\n","createDate":"2019-12-02T06:55:00","status":1,"picture":"https://cdn.clinicways.com/news/87b68c1d-75ae-4b8f-b833-5cc197fdb23e/Main.JPEG","guid":"87b68c1d-75ae-4b8f-b833-5cc197fdb23e","newsType":1,"seoUrl":"what-weekend-anxiety-is-and-how-to-overcome-it","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"If you’ve ever had that feeling on Friday where you`re so worried about how you’ll spend your weekend, you`re not alone.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://brightside.me/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":77,"title":"Exercise Can Make You Happier Than Money, According to Science ","newsContent":"

It’s official: working out can make you happier than money. That is, under the right circumstances, of course. And for those who are not into exercising, there’s nothing to worry about.

\r\n\r\n

We have more good news if you scroll down.

\r\n\r\n

Exercise can make you as happy as a 

\r\n\r\n

$25,000 income increase.

\r\n\r\n

In this study, researchers from Yale and Oxford asked about 1.2 million Americans what their physical routine was,

\r\n\r\n

while on the other hand gathering data about their background(gender, income, marital status, medical history, etc.)

\r\n\r\n

This helped them to find a direct correlation between

\r\n\r\n

happiness and physical activity.

\r\n\r\n

It turns out that people who exercised rated their mental health 43% higher than those who didn’t and had similar backgrounds.

\r\n\r\n

Researchers found out that,in fact, physical activity led the subjects to evaluate their mental health in a similar way

\r\n\r\n

as people who earned $25,000 more than them.

\r\n\r\n

More exercise is not always better

\r\n\r\n

That being said, this doesn’t necessarily mean that you should workout non-stop for hours. From this particular study, researchers concluded that exercising too much can be just as counterproductive for your mental health as not exercising at all. They saw the best results

\r\n\r\n

from people who were physically active for between 30 and 60 minutes, 5 times per week.

\r\n\r\n

Some sports make you happier than others.

\r\n\r\n

They also found that some sports are more effective at making people happy than others. Typically, this includes group sports, since they allow team members to be social, as this study concluded. Oddly, aerobics and cycling offer the same benefits, despite not being classified as group sports

\r\n\r\n

The 20-minute aerobic routine

\r\n\r\n

Finally, according to this study carried out by the University of Vermont, just 20 minutes of daily moderately intense

\r\n\r\n

exercise can help boost your happiness for up to 12 hours.

\r\n\r\n

You can warm up by walking in place for 4 minutes while gradually incorporating other exercises like rolling

\r\n\r\n

your shoulders back, clapping your hands in the air, and doing lunges or high knees.

\r\n\r\n

You can then alternate between boxer shuffles, front kicks, and butt kicks for 5 more minutes.

\r\n\r\n

Then alternate front and back kicks for 2 minutes and do jumping jacks for one minute. Then repeat the

\r\n\r\n

whole routine or try out a new one.

\r\n\r\n

Finally, hold a plank position for a minute before enjoying the benefits of a healthy workout!

\r\n\r\n

\r\n","createDate":"2019-12-01T12:43:00","status":1,"picture":"https://cdn.clinicways.com/news/36357336-cd61-4aae-8502-a74c0e70d070/Main.JPEG","guid":"36357336-cd61-4aae-8502-a74c0e70d070","newsType":1,"seoUrl":"exercise-can-make-you-happier-than-money-according-to-science","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"It’s official: working out can make you happier than money.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":"https://brightside.me/","categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":74,"title":"8 Important Health Tests You Can Do at Home","newsContent":"

1. The liver

\r\n\r\n

Take a look in a mirror that allows you to see your whole body. Do you see a fatty layer above your waist? It’s visceral fat that surrounds the liver and doesn’t allow it to work properly.

\r\n\r\n

Yellowing whites of the eyes, lumps of fat (especially on your eyelids) and a coated tongue also indicate that something’s wrong with your liver.

\r\n\r\n

Please keep in mind that these tests can’t be used to diagnose a disease. These are just a few methods that can help you take care of your health.

\r\n\r\n

How often do you usually visit the doctor to undergo a preventive medical examination?

\r\n\r\n

2. The hearing system

\r\n\r\n

Try to hear what people are talking about from a distance of 16-19 ft. If you can’t understand anything, you probably have to visit a doctor.

\r\n\r\n

Such a method won’t work in crowded places. For example, in a café with loud music, you won’t be able to hear a person speaking near you. This is due to the masking effect: a weak sound gets masked in the presence of a strong noise.

\r\n\r\n

In addition to this test, there are many apps that can check your hearing

\r\n\r\n

3. Eyesight

\r\n\r\n

Look at a window frame for 30 seconds and then close your eyes. Then open your left eye, close it, and open your right eye. If the picture that you see with your eye gets blurred and lines aren’t parallel to each other anymore, it may be a sign of macular degeneration or severe irreversible vision loss.

\r\n\r\n

You can also perform another test near a car parking lot. Step away from any car at 65 ft and try to read a vehicle number plate. If you can’t do that, it’s recommended that you visit a doctor.

\r\n\r\n

4. Bones

\r\n\r\n

Take a look at your nails — they can tell a lot about your health. If your nails become rippled and split or white spots appear, it’s not only a cosmetic problem. Such a condition may indicate that your body doesn’t get enough vitamin B, iron, or that there’s a risk of osteoporosis.

\r\n\r\n

5. The respiratory system

\r\n\r\n

This method is called the Shtange test. You’ll need a stopwatch to perform it.

\r\n\r\n

Stand up and check your heart rate for 30 seconds. Then sit down and take 3 breaths in a row without exhaling. Then hold your breath as long as you can and count the time. After you exhale, check your pulse for 30 seconds again.

\r\n\r\n

Results:

\r\n\r\n

\r\n\t
If you were able to take your breath for less than 40 seconds, the work of your respiratory system isn’t that good. The average result should be 40-49 seconds. If you can hold your breath for more than 50 seconds, you’re in really good shape.
\r\n\t
\r\n\t
Calculate your heart rate using this formula:
\r\n\t

\r\n\r\n

The result should equal your heart rate for 30 seconds after the test and your heart rate for 30 seconds before the test.

\r\n\r\n

The result that equals 1, 2, or lower is fine. If you scored more “points”, it might indicate that your cardiovascular system needs more oxygen.

\r\n\r\n

6. The spine

\r\n\r\n

You’ll need 2 scales. Stand on one scale with one foot and on another scale with the other foot. The weight distribution should be about the same. If numbers differ greatly, it may indicate that your hip bone, the spine, and the head are off-center. It’s probably time to visit a doctor who will prescribe all necessary examinations.

\r\n\r\n

7. The brain

\r\n\r\n

You’ll need a blank sheet, a highlighter or a pencil, and a friend’s help. Draw a clock and ask another person to say the time (hours and minutes). For example, 10:10 AM. Then draw minute and hour hands so that they show the time your friend indicated.

\r\n\r\n

This test involves lots of processes in our brains. The parts of the brain responsible for arm movement, spatial, and visual perception start working harder and that’s why the inability to draw a clock and clock hands may be signs of early dementia.

\r\n\r\n

8. The endocrine system

\r\n\r\n

One of the main health indicators is your waist size. Take some measuring tape and measure your waist at 1 in above the navel. If everything is normal, its size shouldn’t be more than 34 in on women and 40 in on men.

\r\n\r\n

People who have a bigger waist are 5 times more likely to get type 2 diabetes. In Japan in 2008, the government even decided to enact a law obliging people with big tummies to attend special sessions to lose weight.

\r\n\r\n

\r\n","createDate":"2019-11-27T12:34:00","status":1,"picture":"https://cdn.clinicways.com/news/1329ba86-ccdc-48ed-8381-b5fca0da8b0c/Main.JPEG","guid":"1329ba86-ccdc-48ed-8381-b5fca0da8b0c","newsType":1,"seoUrl":"8-important-health-tests-you-can-do-at-home","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"These methods will help you understand whether it's high time you turned to an expert or if it's just fine and there's no need to worry.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":71,"title":"Climate change: Rising heart attack risk due to heat","newsContent":"

Cardiac or myocardial infarction is the leading cause of death worldwide. Scientists at Helmholtz Zentrum München, together with colleagues from other Bavarian research institutions, have now presented a study in the European Heart Journal, which shows that the risk of suffering a heart attack due to increased outside air temperatures has increased significantly in recent years. The risk of cold has not changed significantly over time.

\r\n\r\n

\r\nEnvironmental factors can affect the human cardiovascular system. It has long been suspected that high temperature rashes can increase the risk of heart attack. "Especially for very low and very high temperatures that has been shown well. In the current study, we wanted to check how the risk of heart attack has changed over the years due to heat and cold. " Kai Chen, scientist at the Institute of Epidemiology at Helmholtz Zentrum München.

\r\n\r\n

Together with colleagues from the Ludwig-Maximilians-Universität München, the Augsburg University Hospital and the hospital in Nördlingen, he examined data from the Augsburg Heart Attack Register. Over 27,000 cases of heart attack were included between 1987 and 2014. The average age of those affected was around 63 years, 73 percent of whom were men and around 13,000 cases were fatal. These individual infarcts were examined together with the meteorological data of the respective day and the previous days, and possible other factors such as weekdays or socioeconomic status were excluded. The most important finding from the study: "Over the course of 28 years, we have been able to detect an increased heat-induced risk of heart attack in recent years," says first author Kai Chen.

\r\n\r\n

The researchers compared the results from 1987 to 2000 with those from 2001 to 2014. "The research has shown that, more recently, the risk of heart attack increases more rapidly as the average daily temperature increases than in the previous study period," says Kai Chen. In particular, people who are pre-stressed by diabetes or elevated blood lipid levels are particularly vulnerable today. The researchers suspect that this is partly due to global warming, but also increased risk factors for a heart attack, such as diabetes or hyperlipidemia, and thus make the population more susceptible to heat.

\r\n\r\n

Climate change as a heart attack risk?

\r\n\r\n

"Our study suggests that high temperatures as a trigger for a heart attack should be considered more often, especially with regard to climate change," explains study leader Dr. med. Alexandra Schneider. "Extreme weather events like the 2018 heatwaves in Europe could lead to an increased incidence of cardiovascular disease in the future. At the same time, it would be expected that cold-related heart attacks would become rarer. Our evaluations indicated a lower risk for the later period, but the risk drop was not significant and even very cold days are still considered to be a possible trigger for a heart attack. To what extent the increase in heat-related heart attacks and the decrease in cold-related heart attacks in the future keep the balance, you have to see, "said the epidemiologist. The working group is currently working on projections that model these developments, both for compliance and failure to meet the objectives of the Paris Climate Agreement (1.5 ° C and 2 ° C as targets). In addition, the researchers want to confirm the results obtained in Augsburg in further multicenter studies.

\r\n","createDate":"2019-11-26T19:58:00","status":1,"picture":"https://cdn.clinicways.com/news/dc889631-b5e3-4c87-bd32-ddd387133b88/Main.JPEG","guid":"dc889631-b5e3-4c87-bd32-ddd387133b88","newsType":1,"seoUrl":"climate-change-rising-heart-attack-risk-due-to-heat","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Cardiac or myocardial infarction is the leading cause of death worldwide.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":68,"title":"New barcode technology enables targeted insights into individual cells","newsContent":"

The analysis of gene products in cells is an important tool for the diagnosis of diseases and the design of new drugs in biological and medical research. At Helmholtz Zentrum München, a method of RNA sequencing (transcriptome analysis) has now been developed that pinpoints the smallest quantities of gene transcripts in individual cells. The method allows individual molecules selected in a sample to be labeled and enriched to study their cellular function. This makes it possible to selectively characterize genes in their cellular environment with high accuracy. The work has now been published in Genome Biology.

\r\n\r\n

Single-cell RNA sequencing relies on the study of molecular transcripts created by active regions of the genome in individual cells. Depending on the type and stage of development, cells activate different genes, which are read by RNA molecules and translated into proteins. The number of mRNA molecules or transcripts per gene in a given cell can inform us about their identity and their physiological response to internal or external signals. These can be diseases, aging processes, environmental influences or reactions to pharmacologically active substances. However, the detection of genes that are only expressed in moderate to low concentrations poses major challenges to currently used single-cell RNA sequencing techniques. The analysis primarily identifies so-called housekeeping genes, which, in contrast to dynamically regulated genes, are constantly expressed.

\r\n\r\n

This problem bypasses that of a team around Dr. Micha Drukker, Institute of Stem Cell Research, and PhD student Fatma Uzbas developed the BART-Seq method by enriching selected transcripts for sequencing. BART-Seq stands for "Barcode Assembly for Targeted Sequencing". Primer sets and DNA barcodes are combined so that they can amplify the transcripts of desired genes. "We have developed a novel technique for indexing primers with DNA barcodes through a simple synthesis reaction," explains Micha Drukker. Sequencing transcripts can be traced back to the individual cells from which they are derived. At the same time, since the analysis targets only the selected genes, it is possible to obtain high-resolution information about these genes and thus to characterize each cell individually.

\r\n\r\n

The process is inexpensive and does not require specialized and expensive instrumentation. Any research group with access to next-generation sequencing instruments can use BART-Seq for both single-cell and aggregate analysis of RNA or genomic DNA from thousands of samples.

\r\n\r\n

Together with Philipp Angerer, Nikola Müller and Fabian Theis from the Institute for Computational Biology of Helmholtz Zentrum München, Drukkers has developed software for the design of primers and barcodes as well as for the analysis of sequencing data. To make the method accessible to all research groups, the software is freely available on the internet.

\r\n\r\n

Micha Drukker and his teammates want their process to become an integral part of the Basic and Application Research Toolkit. Especially drug screening projects, such as measuring the response of cultured β-cells to drugs or, for example, targeting genome sequences with CRISPR-Cas9 could benefit greatly from BART-Seq.

\r\n","createDate":"2019-11-26T19:41:00","status":1,"picture":"https://cdn.clinicways.com/news/50f64d41-4871-47aa-aef3-9e237b6746e6/Main.JPEG","guid":"50f64d41-4871-47aa-aef3-9e237b6746e6","newsType":1,"seoUrl":"new-barcode-technology-enables-targeted-insights-into-individual-cells","author":null,"categoryid":8,"mainCategoryid":0,"categoryName":"Göz Cerrahisi","shortDescription":"The analysis of gene products in cells is an important tool for the diagnosis of diseases and the design of new drugs in biological and medical research.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-other","categorycolor":"10c45c","language":"En","newsList":[],"doctors":[]},{"newsid":65,"title":"Better care for hip and knee problems: Quality contract should avoid unnecessary surgery","newsContent":"

Berlin, 19 November 2019 - In 2018, there were complications in 24,700 out of 434,000 hip and knee joint implantations in Germany. According to the Institute for Quality and Transparency in Health Care, more than 11,500 people insured by law were using artificial joints, even though it was medically unnecessary. In order to improve patient care, BARMER has concluded a quality contract with two specialist clinics in this field. "Together with the German Center for Orthopedics at the Waldkliniken Eisenberg we want to avoid the medically unnecessary use of artificial hip and knee joints and reduce the complication rate. Legislators have made it possible to conclude such quality contracts with the Hospital Structure Act, which we expressly welcome, "says Dr. med. Mani Rafii, board member of BARMER. Since 1 November, the quality contract has foreseen cooperation with the German Center for Orthopedics at the Waldkliniken Eisenberg. In the course of the year 2020 the hospital Tabea in Hamburg will be added. If the contract proves itself to be continued indefinitely, says Rafii. For this, the legislator must create a legally binding framework.
\r\nContract should avoid suffering and increase quality of life

\r\n\r\n

\r\nThe cooperation began in two places, so that the insured with knee and hip problems can be spared unnecessary suffering and their quality of life could increase, so the BARMER board on. First, it is about a better quality in the indication. The physicians examined more structured and comprehensive, if and how a patient actually needs to be operated on. If it allows the disease, first a conservative therapy. If the procedure was unavoidable, patients would also be tested for and treated for risky pre-existing conditions such as diabetes or iron deficiency anemia. For without an iron deficiency anemia, in which alone between the years 2006 and 2016 nationwide well over 80,000 patients before knee surgery suffered, for example, the risk of complications are significantly lower. In addition, the life expectancy is higher because the patient does not receive a blood transfusion during the procedure, which is not free of risks. In addition, the rehabilitation will be integrated even more intensively into the care in order to sustainably secure the therapeutic success. So they start as soon as possible after surgery in the clinic before a follow-up rehabilitation follows.
\r\nPatient even more in focus

\r\n\r\n

\r\nProf. Dr. Georg Matziolis, medical director at the German Center for Orthopedics at the Waldkliniken Eisenberg, sees in endoprosthetics in the determination of the disease and the operation preparation still significant potential for improvement. In doing so, one has to take better account of the patient-specific factors than hitherto, as they had a considerable influence on the outcome of the operation. "It has been underestimated in recent decades, which influence the patient with his personality, the side-diseases and the medication on the treatment outcome. This is exactly where we want to work together with BARMER and explore this potential, "says Matziolis. The now planned standardized preoperative screening therefore not only clarifies which other diseases the patient has, whether an intervention is mandatory and whether he must be treated beforehand. It would also record how the patient assesses his quality of life at the beginning of treatment and the severity of his pain. "In terms of a patient-centered approach, we want to capture the individual peculiarities of patients and, if possible, optimize them before surgery," says Matziolis.

\r\n","createDate":"2019-11-25T07:01:00","status":1,"picture":"https://cdn.clinicways.com/news/774ad600-a746-43ed-bd9e-8a677655477d/Main.JPEG","guid":"774ad600-a746-43ed-bd9e-8a677655477d","newsType":1,"seoUrl":"better-care-for-hip-and-knee-problems-quality-contract-should-avoid-unnecessary","author":null,"categoryid":8,"mainCategoryid":0,"categoryName":"Göz Cerrahisi","shortDescription":"Berlin, 19 November 2019 - In 2018, there were complications in 24,700 out of 434,000 hip and knee joint implantations in Germany. According to the Institute for Quality and Transparency in Health Care, more than 11,500 people insured by law were using artificial joints, even though it was medically unnecessary.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-other","categorycolor":"10c45c","language":"En","newsList":[],"doctors":[]},{"newsid":62,"title":"What can help against sleep disorders","newsContent":"

The 60-year-old patient is always tired during the day, although she believes she sleeps well at night. In the Hofheim Sleep Laboratory, senior physician Uwe Fremder found out what the wife is missing after just one computer-controlled night. The examinations revealed that her brain is awake 320 times during the night for ten to fifteen seconds and "checks the situation", as Stranger explains. The physician calls this phenomenon "mother's sleep", which leads to great daytime tiredness. How many sleep disorders is it usually caused by stress. If the restlessness of the brain persists at night, not only is a short phase as in young mothers affected, this would initially lead to concentration and memory disorders. At the same time, the risks for serious illnesses such as stroke, heart attack, diabetes and high blood pressure rose rapidly.

\r\n\r\n

The battery of such patients is constantly "half empty," reports Stranger. For man must sleep for seven to eight hours at night. As the University of Göttingen found out in a study, restful sleep is essential even for roundworms and in humans the best anti-aging program. About a lack of restful sleep complain according to foreigners about 70 percent of Germans. Among them, pathological illnesses increase from year to year according to the experience of the physician. The three-person team at the Hofheim Sleep Laboratory looks after more than 700 patients on average each year - and is on the rise.

\r\n","createDate":"2019-11-21T11:44:00","status":1,"picture":"https://cdn.clinicways.com/news/810f46dd-49d8-43ac-8edb-3ef0c57264b9/Main.JPEG","guid":"810f46dd-49d8-43ac-8edb-3ef0c57264b9","newsType":1,"seoUrl":"what-can-help-against-sleep-disorders","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"Whether snoring, apnea or sleepwalking: More and more people suffer from sleep disorders - and are permanently tired during the day. Many of them seek help in the sleep laboratory. A visit.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":59,"title":"Helmholtz researchers decipher mechanism of new drugs for the treatment of depression, pain or obesity","newsContent":"

Researchers at the Helmholtz Zentrum München have come one step closer to developing novel, selective drugs for the treatment of psychiatric disorders. They discovered how inhibitors inactivate a special protein that plays a crucial role in various diseases. This mechanism of action can be transferred to other medically relevant proteins, which have so far been difficult to develop specific inhibitors and could therefore contribute to the more efficient development of new drugs.

\r\n\r\n

Depression, chronic pain or being overweight appear at first sight like different illnesses. But a small protein with the abbreviation FKBP51 plays a key role in all three conditions, as several studies prove. Thus, the FKBP51 protein was already known as a target for drug therapies.

\r\n\r\n

The thing has only one catch: FKBP51 can not be inhibited simply by an active ingredient, because the antagonist, the protein FKBP52, structurally too similar. While FKBP52 increases the activity of glucocorticoid receptors **, FKBP51 inhibits them. Glucocorticoid receptors are the "receivers" of stress hormones in the brain. Their activation can lead to long-term psychiatric illnesses. The development of a selective drug that can target between two proteins and inhibit only one of them is therefore essential for the development of an active ingredient without undesirable side effects. The situation can be compared to having to develop a specific key that only fits into the keyhole of FKBP51, but not FKBP52.

\r\n\r\n

As early as 2014, Felix Hausch from the Max Planck Institute of Psychiatry developed the highly specific inhibitor SAFit in order to switch off only the protein FKBP51 and not FKBP52 ***. "The underlying mechanism for this selectivity was unknown," says Prof. Dr. med. Michael Sattler. He is Director of the Institute of Structural Biology at the Helmholtz Zentrum München and the Technical University of Munich.

\r\n\r\n

How do inhibitors work in FKBP51?

\r\n\r\n

To clarify this question, Sattler and colleagues combined different methods. By NMR spectroscopy, the internal motility of the FKBP51 protein was determined to investigate its role for the SAFit drug. Added to this were biophysical measurements of the binding strength and rates of binding, as well as mutation analyzes. If individual bases are exchanged in the associated gene, proteins with altered properties are produced. Thus, it can be seen which amino acids of the protein are required to mediate the binding of an active ingredient.

\r\n\r\n

"We found that SAFit molecules bind to a binding pocket of FKBP51 that is normally hidden and inaccessible," reports Sattler. "The binding site is closed by an amino acid, and is accessible only in less than 1% of all molecules. NMR experiments have shown that this blocking amino acid is mobile and sometimes releases access to the binding pocket. SAFit molecules can now exploit this and dock in the binding pocket. Once bound, the inhibitor then blocks the FKBP51 protein. In FKBP52, there is no such dynamic binding pocket so that the SAFit inhibitors can not bind.

\r\n\r\n

Sattler speaks of a "crucial step in the development of new drugs" because: "The concept discovered here and our methodology can now be transferred to other proteins where it is difficult to develop selective inhibitors." This opens up new possibilities for many diseases with "unmet medical needs".
\r\nThe good, the bad and the spliceosome!
\r\nAs the German Research Center for Health and Environment, Helmholtz Zentrum München pursues the goal of developing personalized medicine for the diagnosis, treatment and prevention of widespread widespread diseases such as diabetes mellitus, allergies and lung diseases. It examines the interaction of genetics, environmental factors and lifestyle. The headquarters of the center is located in Neuherberg in the north of Munich. The Helmholtz Zentrum München employs around 2,500 people and is a member of the Helmholtz Association, which includes 19 scientific-technical and medical-biological research centers with around 37,000 employees.
\r\nThe Institute of Structural Biology (STB) researches the spatial structure of biological macromolecules, analyzes their structure and dynamics, and develops NMR spectroscopy methods for these investigations. The aim is to elucidate molecular mechanisms of the biological activity of these molecules and their involvement in diseases. The structure data is used as a base

\r\n","createDate":"2019-11-20T08:46:00","status":1,"picture":"https://cdn.clinicways.com/news/b7ca7594-1f92-41e5-a986-aab4b6762515/Main.JPEG","guid":"b7ca7594-1f92-41e5-a986-aab4b6762515","newsType":1,"seoUrl":"helmholtz-researchers-decipher-mechanism-of-new-drugs-for-the-treatment-of-depre","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Researchers at the Helmholtz Zentrum München have come one step closer to developing novel, selective drugs for the treatment of psychiatric disorders","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":56,"title":"Diet can affect your body's clock and hormonal responses","newsContent":"

For the first time, a study led by Helmholtz Zentrum München and the German Center for Diabetes Research (DZD) shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels. In particular, the difference between day and night, food intake and fasting as well as rest and activity was observed over a period of 24 hours. The research on mice makes it clear that the daytime-dependent metabolic cycle is altered by a high-calorie diet. Because glucocorticoids are widely used to treat inflammatory conditions, the published findings in the Molecular Cell journal suggest that lean and obese patients may respond differently to steroid therapy. Furthermore, the study illustrates the biological function of the daily rhythm of hormone release - high before waking and feeding, low during sleep and fasting - as well as the daily cycles of sugar and fat storage or release by the liver.

\r\n\r\n

Every cell in the human body is driven by an internal clock that follows the circadian rhythm of 24 hours. It runs synchronously with the natural cycle of day and night, mainly controlled by sunlight, but also by social habits. In a healthy system, the adrenals produce glucocorticoid stress hormones every morning. The release of high levels of glucocorticoid before waking causes the body to use fatty acids and sugars as energy sources. This allows us to start the day. In circadian rhythm disorders (e.g., by shift work or jet lag) and / or changes in the glucocorticoid level (e.g., Cushing's syndrome or long-term clinical treatment), severe metabolic dysregulations such as obesity, type 2 diabetes, or fatty liver disease may occur.

\r\n\r\n

The aim of the research team was therefore to understand the importance of the daily release of large quantities of stress hormones, the influence of these hormones on our internal clock and their role in daily metabolic cycles.

\r\n\r\n

Metabolic processes of glucocorticosteroids in the liver

\r\n\r\n

To study the metabolic functions of glucocorticoids in the liver, researchers characterized the activity of their receptor, the so-called glucocorticoid receptor, with new high-throughput technologies. Every four hours, day and night, they analyzed the liver of mice. Mice were fed either normal or high fat diet. Using state-of-the-art genomics, proteomics and bioinformatics techniques, the team was able to gain an idea of when and where the glucocorticoid receptor exerts its metabolic effects.

\r\n\r\n

The researchers analyzed the effects of daily fluctuations in glucocorticoid release in the 24-hour cycle of liver metabolism. They were able to illustrate how glucocorticoids regulate their metabolism during fasting (when the mice are asleep) and when eating (when they are active) by time-dependent binding to the genome. The study also shows how the majority of the rhythmic gene activity is controlled by these hormones. If this control is lost (in so-called knockout mice), this will affect the sugar and fat levels in the blood. This explains how the liver controls the amount of sugar and fat in the blood differently during the day and night.

\r\n\r\n

As the glucocorticoid receptor is widely used in immunotherapy, the team next examined its genomic effects after injecting the drug dexamethasone, a synthetic glucocorticoid that also activates this receptor. "With this experiment," explains Dr. Fabiana Quagliarini, "we found that the drug response in obese mice differs from that in lean mice. This is the first time we have been able to show that nutrition can alter the hormonal and medicinal reactions of the metabolism. "

\r\n\r\n

New insights for Chronomedizin and the therapy of metabolic diseases

\r\n\r\n

Glucocorticoids are a group of natural and synthetic steroid hormones, such as cortisol. They have potent anti-inflammatory and immunosuppressive properties that can control the activity of the immune system. Therefore, they are widely used in medicine. The main drawback is that glucocorticoids may also cause serious side effects because of their ability to regulate sugar and fat metabolism: patients may develop obesity, hypertriglyceridemia, fatty liver, high blood pressure or type 2 diabetes.

\r\n\r\n

"Understanding how glucocorticoids control the 24-hour cycles of liver gene activity and thus blood sugar and fat levels, we gain new insights into chronic medicine and the development of metabolic diseases. We were able to describe a new relationship between lifestyle, hormones and physiology at the molecular level. This indicates that obese people could react differently to the daily hormone release or to glucocorticoid preparations. These mechanisms are the basis for the development of future therapies, "explains Prof. Henriette Uhlenhaut.

\r\n\r\n

Uhlenhaut headed the research team of the Institute for Diabetes and Obesity, Diabetes and Cancer at Helmholtz Zentrum München, the German Center for Diabetes Research (DZD), the Max Planck Institute of Biochemistry, Northwestern University's Feinberg School of Medicine in Chicago and the School of Life Sciences Weihenstephan at the Technical University of Munich (TUM).

\r\n\r\n

original publication
\r\nQuagliarini et al., 2019: Cistromic reprogramming of the diurnal glucocorticoid hormone response by high-fat diet. Molecular Cell, DOI: 10.1016 / j.molcel.2019.10.007

\r\n\r\n

\r\n","createDate":"2019-11-18T10:44:00","status":1,"picture":"https://cdn.clinicways.com/news/2ddd4915-dc2b-475d-8cb7-70e149fc2929/Main.JPEG","guid":"2ddd4915-dc2b-475d-8cb7-70e149fc2929","newsType":1,"seoUrl":"diet-can-affect-your-bodys-clock-and-hormonal-responses","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"For the first time, a study led by Helmholtz Zentrum München and the German Center for Diabetes Research (DZD) shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":53,"title":"Identification of a ferroptosis suppressor protein enables a new approach to the treatment of cancer","newsContent":"

When using conventional chemotherapy often few cancer cells escape treatment. These develop resistance, which leads to relapses and brings the clinical treatment of a variety of tumor entities to their limits. Metabolic changes, the transition of epithelial cells into cells with mesenchymal properties as well as the immune defense are some of the underlying processes. These have recently been linked to acquired sensitivity to ferroptosis. The so-called "persistent" cancer cells develop a strong dependence on glutathione peroxidase 4 (GPX4), the already known regulator of ferroptosis. GPX4 has heretofore been considered in mammalian cells as the only enzyme system that can effectively reduce and thereby detoxify peroxides in the phospholipid double membrane using the tripeptide glutathione, the natural antioxidant most abundant in mammalian cells.

\r\n\r\n

FSP1 - a strong anti-ferroptotic gene

\r\n\r\n

To explore new ways to use ferroptosis in cancer therapy, the research team first attempted to solve the mystery of why certain cancer cells are resistant to ferroptosis despite the expression of ACSL4 - an already known predictive marker for ferroptosis sensitivity (Doll et al. Nat. Chem. Biol. 2017). The research team around Dr. Sebastian Doll and dr. Marcus Conrad from the Institute of Developmental Genetics of Helmholtz Zentrum München and Dr. med. Florencio Porto Freitas and dr. José Pedro Friedmann Angeli of the University of Würzburg (Rudolf Virchow Institute) used a cDNA library from a ferropto-resistant breast cancer cell line. The aim was to find new genetic ferroptosis suppressors. They succeeded in identifying and describing FSP1, previously erroneously referred to as AIFM2 (Apoptosis Inducing Factor Mitochondria Associated 2), as an anti-ferroptotic gene.

\r\n\r\n

FSP1 can completely compensate for the loss of GPX4, the hitherto only known enzyme that can prevent lipid peroxidation and associated ferroptosis. In determining the biochemical function of FSP1, the researchers found that inhibiting lipid peroxidation is dependent on the presence of ubiquinone-10 (also known as coenzyme Q10).

\r\n\r\n

"The mechanism by which FSP1 protects cells from ferroptosis is unique and novel. FSP1 keeps ubiquinone-10 in its reduced state, thereby preventing radical chain reactions that would damage the cell membrane. In the end, we found that this is the mechanism that prevents ferroptosis, "explains Dr. Friedman Angeli.

\r\n\r\n

"In a next step, we investigated around 10,000 drug-like compounds in a phenotypic, cell-based, screen- and target-oriented validation test, thus identifying the first FSP1 inhibitor (iFSP1)," Dr. Bettina Proneth of the team at Helmholtz Zentrum München.

\r\n\r\n

Dr. Sebastian Doll, lead author of the study, continues, "Since we have found that FSP1 is expressed in most cancer cell lines, novel FSP1 inhibitors are interesting candidates for the development of anticancer drugs."

\r\n\r\n

Important impetus for future cancer therapies based on ferroptosis

\r\n\r\n

In this study, the research team describes a previously unknown mechanism for protecting cells from the ferroptotic cell death caused by lipid peroxidation. It was able to show that this system can offer strong resistance to known ferroptosis-inducing drugs. In addition, the researchers provide an explanation for the longstanding mystery of why cells contain large amounts of extra-mitochondrial ubiquinone-10.

\r\n\r\n

"This study has far-reaching implications: it requires the development of novel and target-based ferroptosis inducers. She suggests the development of FSP1 as a biomarker for future ferroptosis-based therapies. Last but not least, it requires the reassessment of ubiquinone-10 as a powerful anti-ferroptotic agent, "concludes Dr. Marcus Conrad.

\r\n\r\n

Cancer therapy is often highly effective in the early stages of treatment, but in many cases the patient's tumor no longer depends on it. Since certain refractory tumors, especially those that have undergone dedifferentiation, develop a ferroptosis-sensitive condition, pro-ferroptotic treatment paradigms based on the inhibition of FSP1, GPX4, or a combination thereof, must be used in the clinic in the future.

\r\n\r\n

Munich at the center of international research

\r\n\r\n

This research was funded by the Development Grant of Helmholtz Zentrum München for FSP1 inhibitors (2018) and the German Research Foundation. The study was initiated by the Helmholtz Zentrum München and in close cooperation with the Rudolf Virchow Center

\r\n","createDate":"2019-11-15T07:05:00","status":1,"picture":"https://cdn.clinicways.com/news/f47c065a-d13e-4667-98dd-1610647fdd2b/Main.JPEG","guid":"f47c065a-d13e-4667-98dd-1610647fdd2b","newsType":1,"seoUrl":"identification-of-a-ferroptosis-suppressor-protein-enables-a-new-approach-to-the","author":null,"categoryid":11,"mainCategoryid":0,"categoryName":"Check Up","shortDescription":"A team of researchers led by the Helmholtz Zentrum München and the University of Würzburg identified an enzyme that protects against iron-dependent cell death, ferroptose: ferroptosis suppressor protein-1, or FSP1 for short.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-check-up","categorycolor":"eab830","language":"En","newsList":[],"doctors":[]},{"newsid":50,"title":"HIGHER IMPF QUOTE AIMED: \"Firewall for the body\" of elementary school students","newsContent":"

With the new campaign "Firewall for the body" Hessen's Ministry of Health wants to increase the vaccination quotas, above all with primary school children. Among other things, posters and flyers should remind parents to keep the vaccination status of their children in mind, said Health Minister Kai Klose (The Greens) in Wiesbaden.

\r\n\r\n

It has not become routine in any family practice to specifically ask patients for their vaccination record. This should change according to the ideas of the Minister.

\r\n\r\n

Vaccination rate must be 95 percent or more
\r\n"Our goal is to make vaccination a matter of course and to increase awareness of community protection as far as it can be achieved through vaccination," said Klose.

\r\n\r\n

With a vaccination rate of 95 percent or more, people who are not allowed to be vaccinated for medical reasons, for example, are considered protected. The rate is not reached for many diseases in Hesse.

\r\n","createDate":"2019-11-13T21:55:00","status":1,"picture":"https://cdn.clinicways.com/news/d36debb7-7379-4a98-9342-2d4fdce51414/Main.JPEG","guid":"d36debb7-7379-4a98-9342-2d4fdce51414","newsType":1,"seoUrl":"higher-impf-quote-aimed-firewall-for-the-body-of-elementary-school-students","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"With a new campaign, the Hessian Ministry of Health wants to combat vaccine fatigue. So far, it is not yet routine that the family doctor asks for the vaccination certificate.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":47,"title":"Yotta's Hair Will Soon Be Very Beautiful","newsContent":"

He actually has enough self-confidence, but his light hair made Bastian Yotta (42) obviously a stroke through his "Miracle Morning". Because he no longer wanted to see the hairy suffering in the mirror every morning, he underwent a hair transplant.

\r\n\r\n

Not a sight for the faint-hearted: When the ex-jungle camper in Beverly Hills was discovered by photographers, one still saw many bloody spots on his head. There's even more insights on his Instagram page.

\r\n\r\n

Not only does the man show his new and sharp-edged hairline (including his girlfriend, who pats him on the cheek), there are also photos of Yotta on the operating table and with a freshly taped back of his head, from which the hair roots are taken were.

\r\n\r\n

"I never complain about problems. I'll solve it, "commented the self-proclaimed celebrity millionaire on Instagram to the photos. "With my new look, I feel more 'Yotta' than ever."

\r\n","createDate":"2019-11-08T07:04:00","status":1,"picture":"https://cdn.clinicways.com/news/97ee4da0-5892-49bf-864d-66e1c2c533b3/Main.JPEG","guid":"97ee4da0-5892-49bf-864d-66e1c2c533b3","newsType":1,"seoUrl":"yottas-hair-will-soon-be-very-beautiful","author":null,"categoryid":6,"mainCategoryid":0,"categoryName":"Saç Ekimi","shortDescription":"He actually has enough self-confidence, but his light hair made Bastian Yotta (42) obviously a stroke through his \"Miracle Morning\". Because he no longer wanted to see the hairy suffering in the mirror every morning, he underwent a hair transplant.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-hair","categorycolor":"d94da6","language":"En","newsList":[],"doctors":[]},{"newsid":41,"title":"New potential therapeutic targets for non-alcoholic fatty liver disease discovered","newsContent":"

Rab24 is a small Rab GTPase that has been shown to be a new regulator of mitochondrial activity and plasticity. The research group led by diabetes scientist Anja Zeigerer was able to demonstrate that Rab24 is highly up-regulated in obese NAFLD patients in the liver. In a next step, she was able to show that reducing Rab24 in diet-related obesity models greatly improves liver steatosis and glucose tolerance. This indicates an overall improvement in the health of the liver and organism. Rab24 is therefore a new potential therapeutic target for the treatment of NAFLD.

\r\n\r\n

"The prevalence of type 2 diabetes and its comorbidities, such as NAFLD, is increasing dramatically. Worldwide, 1.8 billion people are affected by NAFLD and there are no approved treatment options on the market. Therefore, it is particularly important to explore new intracellular targets such as Rab24 for possible therapeutic options, "says Anja Zeigerer.

\r\n\r\n

Less Rab24, better function of the mitochondria

\r\n\r\n

In the search for new therapeutic targets, Anja Zeigerer's group focused on components of the intracellular transport system machinery as well as organelle integrity. The group analyzed novel functions of membrane transport candidates in the control of liver glucose and lipid metabolism. The team discovered Rab24 as a new regulator of the dynamics of mitochondria and energy metabolism.

\r\n\r\n

The dynamics of mitochondria is strongly regulated by their plasticity and turnover, which in turn is controlled by the availability of nutrients. Fasting inhibits mitochondrial division and induces highly interconnected and functional mitochondria that can utilize all available substrates for energy production. In metabolic diseases with a constant supply of food, the mitochondria are fragmented, which greatly reduces their activity and breathability.

\r\n\r\n

The group found that Rab24 affects the machinery responsible for mitochondrial division, and that the mitochondria are better connected by the reduction of Rab24 and therefore more functional. Interestingly, the group noted an accumulation of Rab24 in the liver of overweight patients with NAFLD. This accumulation could lead to an increased number of fragmented mitochondria and increased energy storage in these patients. The data obtained from the reduction of Rab24 in diet-related obesity models offers the prospect of therapeutic use of cellular regulators - such as Rab24 for NAFLD. In addition, the results emphasize a functional relationship between intracellular membrane transport and systemic metabolic dysfunction.

\r\n\r\n

"In a next step, we want to investigate Rab24 as a potential therapeutic target for NAFLD. Our goal is to find inhibitors that inhibit the effect of Rab24 on mitochondrial division and to test whether such inhibitors can mimic the observed improvements in this study, "said Susanne Seitz, lead author of the study.

\r\n\r\n

Strong internal institutional cooperation and financing

\r\n\r\n

The study was conducted under the supervision of Prof. Stephan Herzig, Director of the Institute for Diabetes and Cancer. It benefited greatly from the infrastructure of the Helmholtz Zentrum München: Inspired by a collaboration with the German Mouse Clinic and Prof. Martin Hrabe de Angelis, Institute for Experimental Genetics; supported by the Leipzig satellite institute HI-MAG in collaboration with Prof. Matthias Blüher, who provided valuable human samples for expression analysis; and funded by the German Research Foundation (DFG), the European Diabetes Foundation (EFSD) and the German Center for Diabetes Research (DZD).

\r\n\r\n

Original Publication:
\r\nAnja Zeigerer et al., 2019: Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity. Nature Metabolism, DOI: 10.1038 / s42255-019-0124-x

\r\n\r\n

As the German Research Center for Health and Environment, Helmholtz Zentrum München pursues the goal of developing personalized medicine for the diagnosis, treatment and prevention of widespread widespread diseases such as diabetes mellitus, allergies and lung diseases. It examines the interaction of genetics, environmental factors and lifestyle. The headquarters of the center is located in Neuherberg in the north of Munich. The Helmholtz Zentrum München employs around 2,500 people and is a member of the Helmholtz Association, which includes 19 scientific-technical and medical-biological research centers with around 37,000 employees.
\r\nThe Institute for Diabetes and Cancer (IDC) is a member of the Helmholtz Diabetes Center (HDC) at Helmholtz Zentrum München

\r\n","createDate":"2019-11-02T06:25:00","status":1,"picture":"https://cdn.clinicways.com/news/2d361bb1-6217-4390-bd40-6f744bc9a12d/Main.JPEG","guid":"2d361bb1-6217-4390-bd40-6f744bc9a12d","newsType":1,"seoUrl":"new-potential-therapeutic-targets-for-non-alcoholic-fatty-liver-disease-discover","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"One of the most important comorbidities in type 2 diabetes is nonalcoholic fatty liver (NAFLD).With the world's increased incidence of ...","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":44,"title":"Study on the early detection of type 1 diabetes reaches milestone and will continue","newsContent":"

Type 1 diabetes is the most common childhood metabolic disorder. Since 2015, the world's first population-wide screening test for type 1 diabetes in children has been carried out in Bavaria under the name "Fr1da - Type 1 diabetes: Early detection - early good treatment". By participating in "Fr1da", many children have already been diagnosed in good time and saved from the risk of a life-threatening metabolic derailment. The free screening is done with a simple blood test in children aged 2 to 5 and now 9 to 10 years of age under the study name "Fr1da-plus". Participant 100,000 is now the two-year-old Simon from Ingolstadt.

\r\n\r\n

The patron of "Fr1da", Bavaria's Minister of Health Melanie Huml, emphasized: "The Fr1da study is a flagship for health research in Bavaria and I am delighted that so many children have already benefited from this unique offer and that even more families will benefit from it in the future My goal is to make parents more aware of diabetes in children, and around 4,500 children, adolescents and young adults under the age of 20 are affected by the chronic metabolic disease type 1 diabetes, which has not been curable so far. "

\r\n\r\n

The vast majority of families could breathe again after the test: no type 1 diabetes. If an early stage is excluded during the examination, the likelihood of the disease occurring later is very low.

\r\n\r\n

"Type 1 diabetes affects more children every year, and in most cases, families are coldly surprised by the diagnosis. Particularly serious are those cases that are hospitalized with a dangerous metabolic imbalance (ketoacidosis), because the first symptoms have gone undetected. The early detection study enables the timely sensitization and training of parents and can thus help to avoid this sometimes life-threatening condition, "said Prof. Dr. med. Matthias Tschöp, CEO of Helmholtz Zentrum München.

\r\n\r\n

Children who were diagnosed with early-stage type 1 diabetes in the Fr1da study were given an individual plan. The affected families were personally informed, trained and advised. The opportunity to benefit from the prevention study "Frda-Insulin Intervention" was taken up by 158 families. In the "Fr1da Insulin Intervention" trial, oral insulin attempts to slow or stop the progression of the disease.

\r\n\r\n

"Our goal is to delay or prevent the progression of the autoimmune disease type 1 diabetes by treatment with oral insulin," explains Prof. Dr. med. Anette-Gabriele Ziegler, Director of the Institute for Diabetes Research at Helmholtz Zentrum München. "Because we are committed to not just diagnose and treat early, but to find a way to prevent type 1 diabetes. We work for a world without type 1 diabetes. "

\r\n\r\n

The Augsburg pediatrician Martin Lang, Country Chairman of the Professional Association of Paediatricians in Bavaria and board member of PaedNetz Bayern eV confirms: "Demand shows us that families have a strong interest in having their children examined for an early stage of type 1 diabetes to let. That is why I and about half of all Bavarian paediatricians support the early detection of this chronic disease. We are glad that the possibility of early diagnosis with "Fr1da-plus" continues to be assured. "

\r\n\r\n

Type 1 diabetes screening helps to detect the disease at an early stage and thus to treat it well. Life-threatening over-sugarings are avoided. The families can be trained early and looked after as well as possible. In addition, participation in innovative prevention studies is possible.

\r\n\r\n

Family Pröhl, who participated in the "Fr1da" study with their children, says: "We immediately agreed that our children should benefit from the free early detection. Of course we were relieved when nothing was found in our children. If the result had been different, we would have wanted to know it as soon as possible. Only then could our two have been treated optimally and early. "

\r\n\r\n

Additional Information

\r\n\r\n

\r\nType 1 Diabetes

\r\n\r\n

Type 1 diabetes is an autoimmune disease. This means that the immune system, which primarily fends off pathogenic germs, is directed against the body's own structures. In the case of type 1 diabetes, the immune system attacks and destroys the insulin-producing cells of the pancreas. Insulin is a vital hormone that transports the sugar absorbed from food into the cells from the blood. Can the body produce little or no insulin itself?

\r\n","createDate":"2019-11-01T04:40:00","status":1,"picture":"https://cdn.clinicways.com/news/851ffe88-8724-4a0d-ae9d-4cce6cd744ee/Main.JPEG","guid":"851ffe88-8724-4a0d-ae9d-4cce6cd744ee","newsType":1,"seoUrl":"study-on-the-early-detection-of-type-1-diabetes-reaches-milestone-and-will-conti","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"The Institute for Diabetes Research of the Helmholtz Zentrum München has now recorded 100,000 study participants as part of the nationwide \"Fr1da\" study for the early detection of type 1 diabetes.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":38,"title":"Stillstand bei der Gewichtsabnahme im ersten Jahr","newsContent":"

Zwischen dem ersten bis dritten Monat und dem sechsten und neunten Monat nach der Operation, kann es zu einem Stillstand bei der Gewichtsabnahme kommen. Sie sollten wissen, dass dies eine natürliche Konsequenz aus Stoffwechsel und Körpergleichgewicht ist und man sich keine Gedanken darüber machen sollte. Es wird ausreichen, die empfohlenen Ernährungsgewohnheiten bei zu behalten und etwas Geduld zu zeigen. In Zeiten des Stillstands, sollten Sie Ihre Essgewohnheiten nicht ändern. Diäten außerhalb der Empfehlungen, Begrenzung der Menge an Nahrung, Rückkehr in die flüssige Phase werden nicht empfohlen, denn dadurch kann sich die Fettschicht im Körper vergrößern. Denken Sie daran, Ihr Körper wird einige Zeit brauchen, um sich an die Ernährungsumstellung zu gewöhnen.

\r\n","createDate":"2019-09-24T10:50:00","status":1,"picture":"https://cdn.clinicways.com/news/d908d098-5bec-4869-b401-6ebf7e9c7d0f/Main.JPEG","guid":"d908d098-5bec-4869-b401-6ebf7e9c7d0f","newsType":1,"seoUrl":"stillstand-bei-der-gewichtsabnahme-im-ersten-jahr","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":null,"tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":35,"title":"Kleidungskauf mit Gewichtsänderung","newsContent":null,"createDate":"2019-09-24T10:46:00","status":1,"picture":"https://cdn.clinicways.com/news/20d2e4e3-a1a0-4d44-b0fc-3fd85149afa0/Main.JPEG","guid":"20d2e4e3-a1a0-4d44-b0fc-3fd85149afa0","newsType":1,"seoUrl":"kleidungskauf-mit-gewichts-nderung","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Nach dem bariatrischen Eingriff kommt es sofort zur Gewichtsreduzierung. Die Höhe der Gewichtsänderung ist variabel. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":32,"title":"Körperwahrnehmung","newsContent":"

Forschungen haben gezeigt, dass Adipositas in den letzten Jahren weltweit dramatisch zugenommen hat. Für weitere Informationen über Fettleibigkeit und Adipositas begleitende Krankheiten,

\r\n\r\n

\r\nKörperwahrnehmung ist nicht nur eine Frage der Körperstruktur. (17) Die Körpersensation, mit einer Studie aus dem Jahr 1950, definierte "das Bild unseres eigenen Körpers, das wir in unserem Geist geformt haben, das heißt, wie unser Körper für uns selbst aussieht". Körpergefühl wird von Forschern in verschiedenen Formen als vielseitig definiert. Siehe Tabelle 1 (auf Englisch)
\r\n
\r\nEs gibt keine allgemein akzeptierte Theorie in der Literatur über die Körperempfindung von Patienten mit bariatrischer Chirurgie. Jedoch können Konzepte wie Körperbildangst, Aussehensorientierung, allgemeine Körperbefriedigung, Körperbildvermeidung und Körperkontrolle gesehen werden.
\r\n
\r\nIn modernen westlichen Gesellschaften werden übergewichtige Individuen von der Gesellschaft angezogen und geprägt (1). Bei übergewichtigen Personen sind Unzufriedenheit mit der Körperstruktur und Körperstörungen üblich. (2,3) Die beeinträchtigte Körperempfindung ist nicht für alle adipösen Personen empfindlich. Übergewicht und eine Frau können als Risikofaktoren angesehen werden. Befunde über Veränderungen in der Körperempfindung nach bariatrischer Operation können manchmal widersprechen. Gewichtsverlust, übermäßiger Gewichtsverlust, Ernährungsprobleme mit unterschiedlichen Geschwindigkeiten können die Körperwahrnehmung des Patienten beeinflussen, was in der Forschung als unterschiedlich angesehen wird. (4,5,6,7,8,9,10,11,12). Auf der anderen Seite könnten diese Widersprüche durch den Einsatz verschiedener Sachen verursacht worden sein.
\r\n
\r\nDurch die postoperative Abnahme variiert auch die ideale Körpergröße der Patienten (16). Die Wirkung verschiedener Operationstechniken auf die Art des Körpers ist nicht vollständig verstanden. Die Forscher glauben, dass das veränderte Gehirn-Belohnungssystem positive Auswirkungen auf das Körperbild und die Unzufriedenheit mit der Körperstruktur haben kann. Es gibt auch Hinweise, dass depressive Symptome, die aufgrund von Gewichtszunahme vermindert sind, eng mit dem Körperbild verbunden sind. (5, 14)
\r\n
\r\n
\r\n Biochemiker-Bariatrischer Lebenstrainer
\r\n Alper Habip
\r\n
\r\n
\r\nQuellenangaben:
\r\n
\r\n1.Giel KE, Thiel A, Teufel M, et al. Weight bias in work settings—a qualitative review. Obes Facts. 2010;3:33–40.
\r\n2.Stunkard AJ, Wadden TA. Psychological aspects of severe obesity.Am J Clin Nutr. 1992;55:524S–32S.
\r\n3. Foster GD, Wadden TA, Vogt RA. Body image in obese womenbefore, during, and after weight loss treatment. Health Psychol. 1997;16:226–9.
\r\n4.Schwartz MB, Brownell KD. Obesity and body image. BodyImage. 2004;1:43–56.
\r\n5.Adami GF, Meneghelli A, Bressani A, et al. Body image in obesepatients before and after stable weight reduction following bariatric surgery. J Psychosom Res. 1999;46:275–81.
\r\n6.Hrabosky JI, Masheb RM, White MA, et al. A prospective study ofbody dissatisfaction and concerns in extremely obese gastric bypasspatients: 6- and 12-month postoperative outcomes. Obes Surg.2006;16:1615–21.
\r\n7.Neven K, Dymek M, leGrange D, et al. The effects of Roux-en-Ygastric bypass surgery on body image. Obes Surg. 2002;12:265–9.
\r\n8.Sarwer DB, Wadden TA, Moore RH, et al. Changes in quality of life and body image after gastric bypass surgery. Surg Obes Relat Dis. 2010;6:608–14.
\r\n9.Madan AK, Beech BM, Tichansky DS. Body esteem improves after bariatric surgery. Surg Innov. 2008;15:32–7.
\r\n10. De Panfilis C, Cero S, Torre M, et al. Changes in body image disturbance in morbidly obese patients 1 year after laparoscopic adjustable gastric banding. Obes Surg.2007;17:792–9.
\r\n11.Van Hout GC, Fortuin FA, Pelle AJ, et al. Psychosocial functioning, personality, and body image following vertical banded gastroplasty. Obes Surg. 2008;18:115–20.
\r\n12.van Hout GC, Hagendoren CA, Verschure SK, et al. Psychosocial predictors of success after vertical banded gastroplasty. Obes Surg. 2009;19:701–7.
\r\n13.Hotter A, Mangweth B, Kemmler G, et al. Therapeutic outcome of adjustable gastric banding in morbid obese patients. Eat Weight Disord. 2003;8:218–24.
\r\n14. Masheb RM, Grilo CM, Burke-Martindale CH, et al. Evaluatingoneself by shape and weight is not the same as being dissatisfied about shape and weight: a longitudinal examination in severely obese gastric bypass patients. Int J Eat Disord. 2006;39:716–20.
\r\n15.Munoz D, Chen EY, Fischer S, et al. Changes in desired body shape after bariatric surgery. Eat Disord. 2010;18:347–54.
\r\n16. Martin Teufel & Nicole Rieber ,et al. Body Image After Sleeve Gastrectomy: Reduced Dissatisfaction and Increased Dynamics , OBES SURG (2012) 22:1232–1237
\r\n17. Schilder, P. (1950). The image and appearance of the human body. New York: International Universities Press, Inc.
\r\n18.Varns, Julie Ann, "Body Image and Anthropometric Measurements in Bariatric Surgery Patients" (2016). Dissertations. 128. http://irl.umsl.edu/dissertation/128

\r\n","createDate":"2019-09-24T10:43:00","status":1,"picture":"https://cdn.clinicways.com/news/edede35a-6354-44ca-805c-e1322932664d/Main.JPEG","guid":"edede35a-6354-44ca-805c-e1322932664d","newsType":1,"seoUrl":"korperwahrnehmung","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":"Forschungen haben gezeigt, dass Adipositas in den letzten Jahren weltweit dramatisch zugenommen hat. ","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":29,"title":"Im schlimmsten Fall ist der Haarkranz abgeerntet","newsContent":null,"createDate":"2019-09-19T10:01:00","status":1,"picture":"https://cdn.clinicways.com/news/27066ce7-d092-480e-9016-74e580a95b39/Main.JPEG","guid":"27066ce7-d092-480e-9016-74e580a95b39","newsType":1,"seoUrl":"im-schlimmsten-fall-ist-der-haarkranz-abgeerntet","author":null,"categoryid":6,"mainCategoryid":0,"categoryName":"Saç Ekimi","shortDescription":null,"tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-hair","categorycolor":"d94da6","language":"En","newsList":[],"doctors":[]},{"newsid":26,"title":"Kleine Schraube, großes Problem","newsContent":null,"createDate":"2019-09-19T09:58:00","status":1,"picture":"https://cdn.clinicways.com/news/c787e955-2a57-4399-83ce-fdab450b5e04/Main.JPEG","guid":"c787e955-2a57-4399-83ce-fdab450b5e04","newsType":1,"seoUrl":"kleine-schraube-gro-es-problem","author":null,"categoryid":10,"mainCategoryid":0,"categoryName":"Diş ve Ağız Sağlığı","shortDescription":"Hersteller drücken ihre Implantate in den Markt, die anschließende Kontrolle ist lasch. Obwohl die Medizinprodukte dreimal so oft eingesetzt werden wie künstliche Hüften, weiß man erschreckend wenig.","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-dentist","categorycolor":"076088","language":"En","newsList":[],"doctors":[]},{"newsid":23,"title":"Brustvergrößerung","newsContent":"

Eine Brustvergrößerung ist nach wie vor beliebt bei deutschen Frauen. Seit Jahren steigt die Zahl der Eingriffe kontinuierlich an – jährlich werden mehr als 25.000 Implantate eingesetzt.

\r\n\r\n

Doch die Vorfreude auf neue Brüste wird häufig von Ängsten begleitet. Grund: Oft sind noch viele Fragen zur Brustvergrößerung ungeklärt, die Frauen sind verunsichert.

\r\n\r\n

Vor der OP

\r\n\r\n

Vor jeder Schönheitsoperation sollte man sich ausführlich über die Operation an sich, die Klinik und natürlich auch über Risiken der OP informieren. Gerade bei einer Brustvergrößerung sollte man sich zudem Gedanken über die Größe der Implantate machen.

\r\n\r\n

Für die meisten Frauen ist ein Wert von B oder C die richtige Wahl. Eine größere Oberweite wirkt oft unnatürlich. Besonders bei einer zierlichen Person muss mit Maß gearbeitet werden.

\r\n\r\n

Ein wichtiger Teil bei der Vorbereitung einer Schönheits-OP ist es, sich verschiedene Kliniken anzuschauen und sich einen erfahrenen Chirurgen auszusuchen. Bei einem Beratungstermin werden Sie noch einmal ausführlich über die Operation aufgeklärt.

\r\n\r\n

Ein häufiger Irrglaube ist, dass Frauen über 50 Jahre keine Brustvergrößerung erhalten sollen, weil mit zunehmendem Alter eher Komplikationen bei der Brustoperation vorkommen können. Das stimmt nicht! Denn nicht das Alter ist bei einer Brustvergrößerung entscheidend, sondern ein allgemein guter Gesundheitszustand.

\r\n\r\n

Die Operation

\r\n\r\n

Bei Brustvergrößerungen unterscheiden plastische Chirurgen zwischen drei OP-Methoden. Auch der Sitz des Brustimplantats variiert.

\r\n\r\n

Die OP-Methoden bei der Brustvergrößerung

\r\n\r\n

1. Unter der Brust:

\r\n\r\n

Implantat wird unter der Brust eingeschoben. Vorteil: Brustimplantat sitzt gut. Nachteil: Narbe im Liegen sichtbar.

\r\n\r\n

2. Unter der Achsel:

\r\n\r\n

Implantat wird über die Achseln eingeführt. Vorteil: Narbe gut versteckt. Nachteil: genaue Platzierung schwierig.

\r\n\r\n

3. Über den Warzenhof:

\r\n\r\n

Halbkreisschnitt um die Brustwarze/Mamille, Drüsengewebe wird geteilt, das Brustimplantat hineingeschoben. Vorteil: Eingriff kaum sichtbar. Nachteil: Gewebe kann zerstört werden.

\r\n\r\n

Implantat über dem Muskel

\r\n\r\n

Das Brustimplantat sitzt über der Muskulatur, unter dem Brustgewebe. Funktioniert bei Frauen mit größerer Brust.

\r\n\r\n

Implantat unter dem Muskel

\r\n\r\n

Der Chirurg bildet unter der Muskulatur eine Tasche für das Brustimplantat. Oft wird nur ein Teil der Silikon-Einlage darunter gesteckt. Ist dadurch seltener spürbar.

\r\n\r\n

Das Ergebnis einer Brustvergrößerung wird erst nach einigen Wochen sichtbar. Wenn die Schwellungen der Schönheitsoperation zurückgegangen sind, kann die Frau ihre neuen Brüste anschauen. Erst dann lässt sich sagen, ob der Eingriff das gewünschte Ergebnis gebracht hat.

\r\n\r\n

Risiken einer Brustvergrößerung

\r\n\r\n

Eine Schönheitsoperation, bei der die Brust verändert wird, ist nicht ohne Risiken zu haben. Neben den Operationsrisiken, wie beispielsweise Infektionen, kann es auch zu einer Verkapselung eines Implantats kommen. Dies wird Kapselfibrose genannt und kann dazu führen, dass das Implantat wieder entnommen werden muss.

\r\n\r\n

Fast jede fünfte Frau muss ein zweites Mal unter das Messer, weil das Implantat vom Körper nicht richtig angenommen worden ist oder ein anderes Problem vorliegt.

\r\n\r\n

Das Risiko kann minimiert werden, wenn die Operation von einem erfahrenen Chirurgen durchgeführt wird. Zudem ist es wichtig, erstklassige Materialien zu verwenden.

\r\n\r\n

Ein anderes Problem, dass ebenfalls eine Rolle spielt, ist die Ästhetik. Nicht jede Frau ist mit dem Ergebnis ihrer Brustoperation zufrieden. Da es nicht möglich ist, ganz exakt zu planen, wie die Brust später aussieht, muss die Patientin dem Arzt vertrauen.

\r\n\r\n

Die häufigsten Fragen über Brustvergrößerung – und ihre Antworten:

\r\n\r\n

brigens: Sonne oder Solarium schadet den Brustimplantaten nicht. Allerdings erwärmen sie sich und kühlen langsamer ab als der Rest des Körpers. Jedoch geht davon keine gesundheitliche Gefahr aus. Dafür können die Strahlen die Narben nach einer Brustvergrößerung verstärken und die Schnitte dunkler werden lassen.

\r\n\r\n

Tipp: Warten Sie nach der Brustvergrößerung mindestens ein Jahr, bis Sie sich wieder in der Sonne aalen.

\r\n\r\n

Generell sollten Sie bedenken: Schönheitsoperationen (wie z.B. auch eine Bruststraffung oder eine Nasenkorrektur) sind keine Kleinigkeit, denn jeder Eingriff birgt ein gewisses Risiko. Die Verbraucherzentrale Berlin rät dringend, sich vor einer ästhetischen OP umfassend über Risiken, Kosten und Operationsmethoden zu informieren und genau abzuwägen, ob aus Ihrer Sicht die Vorteile überwiegen.

\r\n\r\n

Brustvergrößerung mit Eigenfett

\r\n\r\n

Eine Alternative zu den gängigen Silikonimplantaten ist die Brustvergrößerung durch Eigenfett. Durch eine Fettabsaugung (Liposuktion) werden Fettzellen gewonnen, die aufbereitet und in die Brust eingespritzt werden.

\r\n\r\n

Da es sich um körpereigenes Gewebe handelt, sind Abstoßungsreaktionen nahezu ausgeschlossen. Frauen, die sich für die Eigenfett-Methode entscheiden, sollten keine familiäre Krebsvorgeschichte haben. Außerdem dürfen die Brüste nicht allzu sehr hängen und natürlich muss genügend Gewebe für die Fettabsaugung vorhanden sein.

\r\n","createDate":"2019-09-19T09:50:00","status":1,"picture":"https://cdn.clinicways.com/news/5a47abf3-665f-49ad-9677-6e706024fc92/Main.JPEG","guid":"5a47abf3-665f-49ad-9677-6e706024fc92","newsType":1,"seoUrl":"brustvergro-erung","author":null,"categoryid":7,"mainCategoryid":0,"categoryName":"Estetik Cerrahi","shortDescription":"Eine schönere Brust durch Implantate","tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-plastic","categorycolor":"673ab7","language":"En","newsList":[],"doctors":[]},{"newsid":20,"title":"30-prozentige Risikoreduktion: SGLT2-Hemmer Canagliflozin verlangsamt das Nierenversagen bei Patienten mit Typ-2-Diabetes","newsContent":"

ei Patienten mit Typ-2-Diabetes und chronischer Nierenerkrankung kann der SGLT2-Hemmer Canagliflozin ein Nierenversagen aufhalten und schützt zudem vor kardiovaskulären Ereignissen. Das zeigen Ergebnisse der CREDENCE-Studie mit 4.401 Patienten, die auf dem World Nephrology Congress in Melbourne präsentiert und im New England Journal of Medicine publiziert worden sind [1].

\r\n\r\n

„Unsere Resultate indizieren, dass eine Behandlung mit Canagliflozin Herz und Nieren von Patienten mit Typ-2-Diabetes und chronischer Nierenerkrankung effektiv schützen kann“, berichtet das internationale Forscherteam unter der Leitung von Prof. Dr. Vlado Perkovic, Leiter des George Institute for Global Health an der University of New South Wales, Sydney, Australien.

\r\n\r\n

Insgesamt kann die Bedeutung von CREDENCE, einer großen und hervorragend durchgeführten Studie, nicht überbewertet werden“, loben Dr. Julie R. Ingelfinger und Prof.Dr. Clifford J. Rosen, Tufts University School of Medicine, Boston, USA, in einem Editorial [2]. „Solche Erkenntnisse werden ganz sicher von Patienten mit Diabetes und chronischer Nierenerkrankung sowie den Ärzten, die sie behandeln, sehr begrüßt werden.“

\r\n\r\n

Nephroprotektion erfolgreich – Studie terminiert

\r\n\r\n

Die Phase-3-Studie mit renalen Endpunkten wurde nach der Randomisierung von 4.401 Patienten Mitte 2018 vorzeitig gestoppt, nachdem eine geplante Interimsanalyse nach durchschnittlich 2,62 Jahren Follow-up eine 30%ige Reduzierung des primären Studienendpunks in der Canagliflozin-Gruppe versus Placebo ergeben hatte. Primärer Endpunkt der Studie war eine Kombination aus terminaler Niereninsuffizienz, mindestens 30 Tage anhaltender Verdopplung des Serum-Kreatinins im Vergleich zum initialen Wert oder Tod aufgrund renaler oder kardiovaskulärer Erkrankungen.

\r\n\r\n

Bereits früher haben die 3 großen kardiologischen Endpunktstudien EMPA-REG OUTCOME, CANVAS und DECLARE-TIMI 58 auf eine mögliche Verbesserung renaler Endpunkte durch diese Blutzuckersenker bei Patienten mit Typ-2-Diabetes hingedeutet.

\r\n\r\n

„Beeindruckt hat mich die Konsistenz der Befunde von CREDENCE im Vergleich zu den Ergebnissen der Progressionsverzögerung der diabetischen Nierenerkrankung in den 3 großen kardiovaskulären Endpunktstudien“, sagt Prof. Dr. Christoph Wanner, Leiter der Nephrologie am Universitätsklinikum Würzburg und Co-Autor der EMPA-REG-Studie. Vor allem sei die Risikoreduktion auch im Stadium 3 der chronischen Nierenerkrankung prominent nachweisbar gewesen; „ein Befund, der bisher nur auf sehr kleinen Zahlen in den vorherigen Studien beruhte“.

\r\n\r\n

Länger leben ohne Dialyse

\r\n\r\n

Die randomisierte Doppelblind-Studie CREDENCE (Canagliflocin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation) hat einen nephroprotektiven Effekt von Canagliflozin (Tagesdosis: 100 mg) gegenüber Placebo bei 4.401 Patienten mit Typ-2-Diabetes und chronischer Niereninsuffizienz untersucht.

\r\n\r\n

Die mittlere glomeruläre Filtrationsrate (GFR) der Patienten (Durchschnittsalter: 63 Jahre) betrug 56,2 ml/Minute/1,73 m2, der mittlere Albumin-Kreatin-Quotient lag bei 927. Bei rund 60% lag die GFR unter 60 ml/Minute/1,73 m2. Alle Teilnehmer wurden mit einem Renin-Angiotensin-System (RAS)-Blocker behandelt, dem aktuell einzigen für die Nephroprotektion bei Typ-2-Diabetes zugelassenen Medikament.

\r\n\r\n

Nach einem mittleren Follow-up von 2,62 Jahren lag das relative Risiko für den primären Endpunkt in der Canagliflozin-Gruppe um 30% unter dem der Kontrollgruppe; bei einer Beschränkung auf die renale Komponente des primären Endpunkts betrug die relative Risikoreduktion sogar 34%.

\r\n\r\n

Auch beim sekundären Endpunkt, kardiovaskulärer Tod oder Hospitalisierung aufgrund einer Herzinsuffizienz profitierten die Patienten in der Interventionsgruppe (-31%).

\r\n\r\n

„Diese Effekte wurden deutlich, obwohl sich die Gruppen nur geringfügig unterschieden hinsichtlich Blutzuckerspiegel, Gewicht und Blutdruck“, schreiben die Autoren. Das suggeriere, dass der Mechanismus, der dem nephroprotektiven Effekt des SGLT2-Hemmers zugrunde liege, nicht durch den Glukosespiegel beeinflusst werde, sondern sich aus einer Minderung des intraglomerulären Drucks ergeben könnte, vermuten sie.

\r\n\r\n

Erhöhtes Amputationsrisiko nicht bestätigt

\r\n\r\n

Hinsichtlich Komplikationen bestand kein Unterschied zwischen den beiden Gruppen; auch nicht bei Amputationen der unteren Extremitäten oder Frakturen. Das sei „beruhigend und stimme mit anderen Studien zu SGLT2-Hemmern überein, nicht jedoch mit dem CANVAS Programm“. Unter der Therapie mit Canagliflozin hatte sich in dieser Studie ein erhöhtes Amputationsrisiko gezeigt.

\r\n\r\n

Insgesamt sei der nephroprotektive Effekt von Canagliflozin erwartbar gewesen, sagt Wanner. Man sei von einer geplanten Behandlungsindikation für die diabetische Nierenerkrankung (DKD) im Stadium 3 mit einer glomerulären Filtrationsrate im Bereich von 30-60 ml/min/1,73m2 ausgegangen.

\r\n\r\n

„Diese Indikation wird nur auf der Basis von sehr soliden Daten gewährt. Insofern musste CREDENCE derart positive Ergebnisse aufzeigen.“ Unklarheit bestand lediglich hinsichtlich potenzieller Nebenwirkungen wie Fußamputationen. „Diese Bedenken wurden durch CREDENCE nicht bestärkt“, so der Experte.

\r\n\r\n

Nachhaltig verändern werde sich durch die zusätzliche Gabe von Canagliflozin zur Standard-Therapie mit einem RAS-Blocker vor allem die Dialysepflichtigkeit, die in der Studie um rund ein Drittel gesenkt werden konnte, sagt Wanner.

\r\n\r\n

Als Diabetes-Medikament habe der SGLT2-Hemmer bei einer Nierenfunktion unter 60 ml/min/1,73m2 keinen Stellenwert, da die HbA1c-Absenkung mit rund 0,3% zu gering sei, um therapeutisch genutzt zu werden. „Ich sage sogar voraus, dass bei progredienter diabetischer Nierenerkrankung mit Albuminurie ein SGLT2-Hemmer eingesetzt werden wird, ohne den HbA1c-Wert zu kontrollieren“, so seine Prognose.

\r\n\r\n

EMPA-KIDNEY-Studie dauert noch an

\r\n\r\n

Unter Wanners Leitung läuft derzeit noch eine multizentrische, internationale, randomisierte, doppelblinde Placebo-kontrollierte Studie eines SGLT2-Hemmers mit renalen Endpunkten. In der ereignisgesteuerten EMPA-KIDNEY-Studie wird Empagliflozin bei rund 5.000 Patienten mit chronischer Nierenerkrankung mit und ohne Diabetes getestet.

\r\n\r\n

Die Frage sei nämlich, ob auch Nicht-Diabetiker von einer Therapie mit einem SGLT2-Hemmer profitieren. „Da sich der tubulo-glomeruläre Feedback-Mechanismus eventuell auch bei Nicht-Diabetikern durch einen SGLT2-Hemmer aktivieren lässt, wurde die Hypothese aufgestellt, dass auch nicht-diabetische Nierenerkrankungen behandelt werden können z.B. Glomerulonephritis“, sagt Wanner. Das werde derzeit in Studien mit mehreren SGLT2-Hemmern – Dapagliflozin, Empagliflozin und Sotagliflozin – untersucht.

\r\n\r\n

\r\n","createDate":"2019-09-12T13:42:00","status":1,"picture":"https://cdn.clinicways.com/news/9339b5e6-56e8-474b-acd2-12bf4c813b02/Main.JPEG","guid":"9339b5e6-56e8-474b-acd2-12bf4c813b02","newsType":1,"seoUrl":"30-prozentige-risikoreduktion-sglt2-hemmer-canagliflozin-verlangsamt-das-nieren","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":null,"tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":17,"title":"Wie SGLT2-Inhibitoren das Herz und die Nieren schützen – die aktuellsten Erkenntnisse","newsContent":"

Die Natrium-/Glukose-Co-Transporter-2(SGLT2)-Inhibitoren Empagliflozin und Canagliflozin waren die ersten Antidiabetika, für die in großen Endpunktstudien gezeigt worden ist, dass sie vor kardiovaskulären Erkrankungen schützen (primärer Studien-Endpunkt Herzinfarkt, Schlaganfall oder kardiovaskulärer Tod) und – im Fall von Empagliflozin – sogar die kardiovaskuläre und die Gesamtmortalität senken. Auch Klinikeinweisungen wegen Herzinsuffizienz (als sekundärer Studienendpunkt) nahmen ab.

\r\n\r\n

Darüber hinaus sind SGLT2-Inhibitoren offenbar in der Lage, renale Endpunkte wie Nierenfunktionsverlust, Notwendigkeit einer Nierenersatz-Therapie oder Tod durch Nierenerkrankung zu reduzieren. Doch woher kommt der kardiovaskuläre und renale Schutzeffekt der eigentlich als Blutzuckersenker entwickelten Wirkstoffklasse?

\r\n\r\n

In einem State-of-the-Art-Review im Journal of the American College of Cardiology (JACC) geben Dr. Thomas A. Zelniker von der Cardiovascular Division am Brigham and Women’s Hospital in Boston und Prof. Dr. Eugene Braunwald von der Harvard Medical School in Boston einen Überblick über die möglichen kardiovaskulären Wirkmechanismen, „die anders als die hypoglykämischen Effekte der SGLT2-Inhibitoren noch nicht komplett verstanden sind“ [1].

\r\n\r\n

Blutdrucksenkung

\r\n\r\n

Zu den bekannten kardiovaskulären Wirkungen zählt die Blutdrucksenkung durch die SGLT2-Hemmer: So nimmt der systolische Druck um 4 bis 6 mmHg und der diastolische um 1 bis 2 mmHg ab. Die Herzfrequenz bleibt unbeeinflusst. Für die Blutdrucksenkung wird auf kurze Sicht die durch die Substanzklasse verursachte Diurese verantwortlich gemacht. Es zeigte sich aber, dass das Urinzeitvolumen nach 12 Wochen Behandlung wieder auf den Ausgangswert zurückkehrt, während die Blutdrucksenkung bestehen bleibt.

\r\n\r\n

Die Diurese scheint somit nicht der einzige Mechanismus zu sein, über den SGLT2-Inhibitoren den Blutdruck senken. Andere mögliche Mechanismen seien ein Remodeling der Nephronen, eine Verbesserung der Endothelfunktion, eine Reduktion der arteriellen Steifheit oder der glukosurie-bedingte Verlust an Körpergewicht, schreiben Zelniker und Braunwald.

\r\n\r\n

Reduktion von Vor- und Nachlast

\r\n\r\n

Die durch die SGLT2-Inhibition ausgelöste Ausscheidung von Glukose und Natrium im Harn reduziert das Plasmavolumen und senkt die kardiale Vorlast. Die Senkung des arteriellen Druckes und der arteriellen Steifheit wiederum tragen zu einer Reduktion der Nachlast bei.

\r\n\r\n

In diesem Kontext hatte eine exploratorische Analyse der EMPA-REG OUCOME-Studie gezeigt, dass es vor allem Veränderungen von Plasmavolumen-Markern wie Hämatokrit und Hämoglobin sind, die eng mit der Reduktion der kardiovaskulären Mortalität assoziiert sind. Allerdings sei zu bedenken, dass solche retrospektiven Analysen keinen Beweis für einen kausalen Zusammenhang lieferten, schränken Zelniker und Braunwald ein.

\r\n\r\n

Verbesserung der mitochondrialen Effizienz

\r\n\r\n

Auffallend war, dass in der EMPA-REG-Outcome-Studie schon relativ rasch nach Therapiebeginn die kardiovaskuläre Mortalität unter Empagliflozin abnahm. Dafür könnten hämodynamische Effekte verantwortlich sein, so die Überlegung der beiden Autoren. Und die verbesserte Hämodynamik wiederum könnte auf eine verbesserte Mitochondrien-Funktion in den Myokardzellen und damit eine optimierte Herzleistung zurückzuführen sein.

\r\n\r\n

Für die SGLT2-Inhibitoren Empagliflozin, Canagliflozin und Dapagliflozin wurde gezeigt, dass sie den kardialen Na+/H+-Austauscher (ein Membranprotein, das Na+ in die Zelle schleust und im Austausch H+ hinaus) hemmen. Dies führt zu einer niedrigeren Na+-Konzentration im Zytosol und beeinflusst, da Calcium die Herzmuskelzelle über Austausch mit Natrium verlässt, auch die Calcium-Konzentrationen: Ca2+ nimmt im Zytosol ebenfalls ab, doch die Ca2+-Konzentration in den Mitochondrien steigt.

\r\n\r\n

Diese Veränderungen könnten kardioprotektiv wirken, da sowohl eine erhöhte intrazelluläre Na+-Konzentration als auch ein verstärkter Na+-/H+-Austausch mit Arrhythmien, myokardialer Hypertrophie und einer Verschlechterung einer bestehenden Herzinsuffizienz im Zusammenhang stehen“, erklären Zelniker und Braunwald.

\r\n\r\n

Fett als Substrat

\r\n\r\n

SGLT2-Inhibitoren verursachen außerdem rasch hormonelle Veränderungen des Glukose-Stoffwechsels. Nach längerer Behandlung mit den Substanzen nimmt die Oxidation freier Fettsäuren zu, dies stimuliert die Bildung von Ketonkörpern und verstärkt die Nutzung von Fett als Substrat für die Energieproduktion. „Die daraus resultierende verstärkte Verstoffwechslung von Beta-Hydroxy-Butansäure im Herzen könnte zu einer Verbesserung der Mitochondrienfunktion und damit der Myokardleistung beitragen“, schreiben die Autoren.

\r\n\r\n

Reduktion des epikardialen Fettgewebes

\r\n\r\n

Eine erst dieses Jahr veröffentlichte Studie aus Japan zeigt zudem, dass SGLT2-Inhibitoren das epikardiale Fett reduzieren. Diese Fetteinlagerungen zwischen Myokard und viszeraler Schicht des Perikards sind biologisch aktiv. Es wird spekuliert, dass eine Verringerung des epikardialen Fettgewebes die Konzentration schädlicher Stimuli, wie Leptin und Komponenten des Renin-Angiotensin-Aldosteron-Systems (RAAS), die an Entzündungen und fibrotischen Prozessen in Herz und Gefäßen beteiligt sind, reduzieren könnten.

\r\n\r\n

SGLT2-Inhibition in der Niere

\r\n\r\n

Kardiovaskuläre Erkrankungen sind die Haupttodesursache bei Typ-2-Diabetes. Doch mikrovaskuläre Veränderungen tragen zur Entstehung diabetischer Nierenerkrankungen bei, die oft zu terminaler Niereninsuffizienz führen und eine Nierenersatz-Therapie notwendig machen.

\r\n\r\n

„Herz- und Nierenfunktion beeinflussen sich gegenseitig“, betonen Zelniker und Braunwald, „durch systemische Hypertonie, neurohormonelle Aktivierung, Endothel-Dysfunktion und systemische Entzündung“. Insgesamt deute alles auf einen „Teufelskreis aus Typ-2-Diabetes, Herzinsuffizienz und chronischem Nierenversagen“ hin, der durch SGLT2-Inhibitoren möglicherweise durchbrochen wird.

\r\n\r\n

An der Pathogenese der diabetischen Nierenerkrankung sind ein erhöhter intraglomerulärer Druck, glomeruläre Hyperfiltration und fibrotische Prozesse beteiligt. Klinisch zeigt sie sich durch eine Abnahme der glomerulären Filtrationsrate (GFR) und/oder durch zunehmende Albuminurie.

\r\n\r\n

Wie genau die Inhibition von SGLT2 protektiv auf die intrarenale Hämodynamik wirkt – obwohl die GFR nach Behandlungsbeginn sogar leicht abnimmt – ist den beiden Autoren zufolge nicht eindeutig geklärt.

\r\n\r\n

Veränderungen des tubulo-glomerulären Feedbacks – ein Feedback-Mechanismus des renalen Tubulussystems, der die GFR der tubulären Resorption anpasst – könnten eine Rolle bei der neurohumoralen Aktivierung, der Aufrechterhaltung des Flüssigkeitsvolumens und der extrazellulären Elektrolyt-Homöostase spielen, so Zelniker und Braunwald.

\r\n\r\n

Feedback-Effekte oder natriuretisches Peptid

\r\n\r\n

Ein durch die SGLT2-Inhibitoren bedingter Anstieg der Natriumchlorid-Konzentration in der Tubulus-Flüssigkeit könnte aber auch eine Kaskade auslösen, die die GFR durch Verengung der efferenten Glomerulus-Arteriolen senkt. Das tubulo-glomeruläre Feedback supprimiert außerdem die Sekretion von Renin und dadurch die Produktion von Angiotensin 2.

\r\n\r\n

Und es kann zur Erweiterung der efferenten Glomerulus-Arteriolen beitragen, was den hydrostatischen Druck in den Glomeruli und die GFR noch weiter reduziert. Bei Patienten, die mit ACE-Hemmern oder Angiotensin-Rezeptor-Blockern behandelt werden, spielt letzterer Mechanismus allerdings wahrscheinlich eine untergeordnete Rolle, vermuten die beiden Autoren.

\r\n\r\n

Möglicherweise verringere die durch SGLT2-Inhibitoren bedingte Diurese und Natriurese auch die Konzentration an freiem natriuretischem Peptid, auch davon sei eine Verengung der afferenten Tubulus-Arteriolen zu erwarten, so Zelniker und Braunwald.

\r\n\r\n

Schutz trotz leichter GFR-Abnahme

\r\n\r\n

Beide Hypothesen – Veränderungen des tubulo-glomerulären Feedback und Verringerung der Konzentration an freiem natriuretischem Peptid – gehen davon aus, dass die SGLT2-Inhibition anfangs zu einer leichten Abnahme der GFR führt, die Reduktion von Hyperfiltration und intraglomerulärem Druck aber nierenschützend wirkt und so hilft, die Nierenfunktion zu erhalten.

\r\n\r\n

Bei hypovolämischen Patienten sollten SGLT2-Inhibitoren dennoch mit Vorsicht eingesetzt bzw. abgesetzt werden, um eine Verschlechterung der Nierenfunktion zu vermeiden, schränken Zelniker und Braunwald ein.

\r\n","createDate":"2019-09-12T13:41:00","status":1,"picture":"https://cdn.clinicways.com/news/d583cadc-df57-44a6-85bf-7fe89b0e528a/Main.JPEG","guid":"d583cadc-df57-44a6-85bf-7fe89b0e528a","newsType":1,"seoUrl":"wie-sglt2-inhibitoren-das-herz-und-die-nieren-schutzen-die-aktuellsten-erkennt","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":null,"tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":14,"title":"Studie der Superlative bei Typ-2-Diabetes: Dapagliflozin punktet bei Herzinsuffizienz, erfüllt aber nicht alle Erwartungen","newsContent":"

Vorläufige Ergebnisse der bislang größten, längsten und umfassendsten kardiovaskulären Endpunkt-Studie mit einem Medikament gegen Typ-2-Diabetes zeigen, dass der Hemmstoff des Sodium-Glukose Co-Transporters vom Typ 2 (SGLT2) Dapagliflozin (Forxiga®/Farxiga®, AstraZeneca) kardiovaskuläre Endpunkte günstig beeinflusst – dies aber augenscheinlich nur über eine Besserung bei Herzinsuffizienzen.

\r\n\r\n

AstraZeneca hat am Dienstag die Hauptergebnisse ihrer Studie DECLARE-TIMI 58 bekanntgegeben. Die Studie hat den Effekt von Dapagliflozin versus Placebo auf kardiovaskuläre Endpunkte getestet – dies über einen Zeitraum von bis zu 5 Jahren in 33 Ländern bei mehr als 17.000 Erwachsenen mit Typ 2 Diabetes mit mehreren kardiovaskulären Risikofaktoren oder etablierter kardiovaskulärer Erkrankung. Die endgültigen Ergebnisse sollen im November bei den American Heart Association (AHA) Scientific Sessions 2018 in Chicago, USA, vorgestellt werden.

\r\n\r\n

DECLARE ist einzigartig, weil es die erste kardiovaskuläre Endpunkt-Studie mit 2 co-primären Wirksamkeitsendpunkten ist. Und ein großer Prozentsatz der eingeschlossenen Patienten mit Typ-2-Diabetes – rund 60% – galten als Primärprävention, da sie keine offenkundige kardiovaskuläre Erkrankung hatten, sondern nur Risikofaktoren dafür.

\r\n\r\n

Dapagliflozin hat in der Studie den primären Sicherheitsendpunkt erreicht – die Nicht-Unterlegenheit bezüglich schwerer kardiovaskulärer Ereignisse (Major Adverse Cardiovascular Events = MACE) – und reduzierte zudem signifikant den zusammengesetzten Endpunkt aus Hospitalisierung wegen Herzinsuffizienz oder kardiovaskulären Tod, was einer der 2 primären Wirksamkeitsendpunkte war.

\r\n\r\n

Aber obwohl unter Dapagliflozin weniger MACE auftraten, erreichte der Unterschied zu Placebo in diesem Endpunkt (der der 2. Wirksamkeitsendpunkt war) keine statistische Signifikanz, heißt es in der Pressemitteilung des Unternehmens.

\r\n\r\n

Unterscheiden sich die DECLARE Ergebnisse, weil sich die Patientenpopulationen unterscheiden?

\r\n\r\n

Die DECLARE-TIMI 58 Ergebnisse stehen in einigen Aspekten im Kontrast zu denjenigen mit anderen SGLT2-Inhibitoren, etwa EMPA-REG OUTCOME mit Empagliflozin (Jardiance, Boehringer Ingelheim) und rund 7.000 Patienten und Canagliflozin Cardiovascular Assessment Study (CANVAS) mit Canagliflozin (Invokana, Vokanamet, Janssen) mit 10.000 Patienten.

\r\n\r\n

Beide SGLT2-Hemmer, Empagliflozin und Canagliflozin, senkten jeweils die MACE-Rate in ihren Studien – und mit Empagliflozin nahmen sogar die kardiovaskulär bedingten Todesfälle ab. In der Folge sind auch die Produktinformationen der beiden Antidiabetika in der EU geändert worden.

\r\n\r\n

Aber EMPA-REG umfasste fast ausschließlich Typ-2-Patienten in der kardiovaskulären Sekundärprävention (weniger als 1% hatten nur Risikofaktoren) während in CANVAS mehr als 60% der Patienten in der Sekundärprävention waren.

\r\n","createDate":"2019-09-12T12:22:00","status":1,"picture":"https://cdn.clinicways.com/news/e6a5d1a3-f723-4a0a-a2c1-d646dc3e7413/Main.JPEG","guid":"e6a5d1a3-f723-4a0a-a2c1-d646dc3e7413","newsType":1,"seoUrl":"studie-der-superlative-bei-typ-2-diabetes-dapagliflozin-punktet-bei-herzinsuffi","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":null,"tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]},{"newsid":11,"title":"Herzschutz bei Typ-2-Diabetes: ESC-Leitlinie setzt auf SGLT2-Hemmer und GLP-1-Agonisten – Metformin nicht mehr Firstline für alle","newsContent":"

Paris – Die European Society of Cardiology (ESC) hat in Zusammenarbeit mit der European Association for the Study of Diabetes (EASD) eine neue Leitlinie zum Management und zur Prävention der kardiovaskulären Erkrankungen (cardiovascular disease, CVD) bei Patienten mit Diabetes oder Prädiabetes veröffentlicht.

\r\n\r\n

Die Empfehlungen spiegeln die jüngsten positiven Ergebnisse großer kardiovaskulärer Outcome-Studien (CVOT) mit den neuen Diabetes-Wirkstoffen sowie andere neue Entwicklungen wider.

\r\n\r\n

Die Leitlinie ist eine Aktualisierung der Version von 2013: Neben den Hinweisen rund um die neuen Antidiabetika auf der Basis wegweisender Endpunktstudien wird auch Metformin nicht länger als Firstline-Therapie für alle aufgelistet. Und: Primär- und Sekundärprävention sind out, stattdessen soll das kardiovaskuläre Risiko der Patienten in „mittel“, „hoch“ und „sehr hoch“ klassifiziert werden.

\r\n\r\n

Welche Neuerungen gibt es?

\r\n\r\n

„In den vergangenen 5 Jahre erlebten wir die aufregendste Zeit seit Beginn der Diabetesforschung“, sagte Cosentino, „weil wir zum ersten Mal in der Geschichte des Typ-2-Diabetes Daten aus mehreren Endpunktstudien vorliegen haben, die darauf hindeuten, dass der Einsatz von Glukose-senkenden Medikamenten bei Patienten mit kardiovaskulären Erkrankungen oder mit sehr hohem/hohem kardiovaskulärem Risiko einen Nutzen für diese Erkrankungen hat.“

\r\n\r\n

Die Leitlinien stützen sich auf Evidenzen aus den Studien zu SGLT2-Hemmern und GLP-1-Agonisten:

\r\n\r\n

\r\n\t
SGLT2-Hemmer: EMPA-REG-OUTCOME-Studie mit Empagliflozin (Jardiance®, Boehringer Ingelheim/Lilly), CANVAS-Studie mit Canagliflozin (Invokana®, Janssen), DECLARE-TIMI-58-Studie mit Dapagliflozin (Farxiga®, AstraZeneca)
\r\n\t
\r\n\t
GLP-1-Agonisten: LEADER-Studie mit Liraglutid (Victoza®, Novo Nordisk), SUSTAIN-6-Studie mit Semaglutid, Harmony-Outcomes-Studie mit Albiglutid, REWIND-Studie mit Dulaglutid (Trulicity®, Lilly), PIONEER-6-Studie mit Semaglutid, CREDENCE-Studie mit Canagliflozin.
\r\n\t

\r\n\r\n

Ein wesentlicher Punkt der Leitlinie sei es, dass die kardiovaskulären Risiken bei Diabetikern auf der Grundlage von Komorbiditäten und Krankheitsdauer neu klassifiziert wurden, anstatt alles nur als Primär- oder Sekundärprävention kardiovaskulärer Erkrankungen in einen Topf zu werfen.

\r\n\r\n

Nach den Leitlinien werden Diabetiker jetzt wie folgt klassifiziert:

\r\n\r\n

\r\n\t
mittleres kardiovaskuläres Risiko bei jungen Diabetikern ohne weitere kardiovaskuläre Risikofaktoren und noch keine 10 Jahre an Diabetes erkrankt
\r\n\t
\r\n\t
hohes kardiovaskuläres Risiko, wenn der Diabetes länger als 10 Jahre besteht und mindestens ein weiterer Risikofaktor vorliegt, ohne dass Schädigungen an den Zielorganen nachzuweisen wären
\r\n\t
\r\n\t
sehr hohes kardiovaskuläres Risiko, wenn eine kardiovaskuläre Erkrankung oder eine Zielorganschädigung vorliegt oder seit über 20 Jahren ein Typ-1-Diabetes besteht.
\r\n\t

\r\n\r\n

Wir stehen wirklich vor einem großen Paradigmenwechsel. Prof. Dr. Francesco Cosentino

\r\n\r\n

Die Studienresultate legen nahe, dass diese neuen Medikamente für Patienten mit Typ-2-Diabetes und kardiovaskulären Erkrankungen oder sehr hohen/hohen kardiovaskulären Risiken empfohlen werden sollten. Das gilt etwa für Patienten mit Zielorgan-Schädigung oder mehreren kardiovaskulären Risikofaktoren, unabhängig davon, ob sie noch unbehandelt sind oder bereits Metformin erhalten.

\r\n\r\n

„Wir stehen wirklich vor einem großen Paradigmenwechsel“, sagte Cosentino und bezog sich dabei auf die Verwendung von Metformin. Denn: Für Patienten mit Typ-2-Diabetes und manifester kardiovaskulärer Erkrankung, also Hochrisiko-Patienten, empfiehlt die Leitlinie die sofortige Therapieeinleitung mit einem SGLT-2-Hemmer oder einem GLP-1-Agonisten oder eine Ergänzung der bestehenden Metformintherapie.

\r\n\r\n

„Das ist wichtig“, erklärte Grant in einer E-Mail gegenüber Medscape, „denn bisher haben alle Leitlinien Metformin als Erstlinientherapie in allen Fällen von Typ-2-Diabetes empfohlen. Die Evidenzen zeigen jedoch, dass dies nicht mehr die beste Strategie ist.“

\r\n\r\n

Die Leitlinie stellt auch fest, dass der Benefit einer GLP-1-Agonisten-Medikation „höchstwahrscheinlich durch die Reduktion arteriosklerose-bedingter Ereignisse zustande kommt“, während SGLT2-Hemmer eher die Endpunkte im Zusammenhang mit einer Herzinsuffizienz zu reduzieren scheinen.

\r\n\r\n

Die „enormen Veränderungen der letzten 5 Jahre im Diabetesmanagement sind wahrscheinlich die größten Erfolge seit der Entdeckung des Insulins im Jahr 1924“, so Grant.

\r\n\r\n

Die enormen Veränderungen der letzten 5 Jahre im Diabetesmanagement sind wahrscheinlich die größten Erfolge seit der Entdeckung des Insulins im Jahr 1924. Dr. Peter J. Grant

\r\n\r\n

Im Anschluss wies er auf die folgenden wichtigen Aktualisierungen in der aktuellen Leitlinie hin:

\r\n\r\n

\r\n\t
„Wir sollten nicht mehr von Primär- und Sekundärprävention sprechen, sondern Patienten mit Diabetes als Patienten mit mittlerem, hohem oder sehr hohem kardiovaskulären Risiko einstufen.“
\r\n\t
\r\n\t
Eine neue Endpunktstudie zu ASS (ASCEND) bei Diabetikern mit mittlerem kardiovaskulärem Risiko ist der Grund, dass ASS nicht mehr bei Patienten mit mittlerem Risiko empfohlen wird, sondern die Anwendung auf Patienten mit hohem und sehr hohem Risiko auf individueller Basis beschränkt wird.
\r\n\t
\r\n\t
Zwei Studien mit PCSK9-Hemmern – darunter eine Diabetes-Teilstudie – führten dazu, diese bei Hochrisikopatienten mit anhaltend hohen LDL-Werten unter maximaler Statin- und Ezetimib-Behandlung oder bei Statin-Intoleranz zu empfehlen.
\r\n\t
\r\n\t
Die COMPASS-Studie mit Rivaroxaban plus ASS bei Patienten mit stabiler KHK führte zu der Empfehlung, diese duale Therapie zur längerfristigen Prävention kardiovaskulärer Erkrankungen zu empfehlen.
\r\n\t

\r\n\r\n

Gleichzeitig sollte die „glykämische Kontrolle nicht vergessen werden“, warnte Grant, denn sie trage dazu bei, mikroangiopathischen Komplikationen an Augen, Nerven und Nieren vorzubeugen.

\r\n\r\n

Die Leitlinien empfehlen, einen HbA1c-Spiegel von unter 7% anzustreben, insbesondere bei jungen Erwachsenen, die noch nicht lange Diabetiker sind.

\r\n\r\n

Aufgenommen wurden auch LDL-Ziele von 2,5 mmol/l, 1,8 mmol/l und unter 1,4 mmol/l (100/70/55 mg/dl) für Patienten mit Diabetes, die ein mittleres, hohes bzw. sehr hohes Risiko für kardiovaskuläre Erkrankungen haben.

\r\n\r\n

Darüber hinaus wird darauf hingewiesen, dass PCSK9-Hemmer bei Patienten mit Diabetes, die als Hochrisikogruppe für kardiovaskuläre Ereignisse angesehen werden, eindeutig erforderlich sind und dass ASS für diese Patientengruppe in Betracht gezogen werden kann – allerdings nicht mehr bei Patienten mit nur einem mittleren kardiovaskulären Risiko.

\r\n\r\n

Disziplinübergreifende Leitlinien

\r\n\r\n

Dr. Robert H. Eckel von der University of Colorado in Denver – zwischen 2005 und 2006 Präsident der American Heart Association (AHA) und ab Januar 2020 Co-Präsident der American Diabetes Association (ADA) – wurde von Medscape um eine Stellungnahme gebeten und schrieb in einer Mail, dass sich die ambulant tätigen Ärzte im Allgemeinen an die „Standards of Medical Care“ der ADA/EASD für das Diabetesmanagement sowie an die Leitlinien und die Stellungnahmen der AHA und des American College of Cardiology in kardiologischen Fragen hielten.

\r\n\r\n

Diese Version der ESC/EASD-Leitlinien für Diabetiker und kardiovaskulär Erkrankte betone die Bedeutung der SGLT2-Hemmer und GLP-1-Agonisten. „Das schließt die Positionierung als Primärtherapie gegenüber dem Metformin bei Patienten mit hohem oder sehr hohem kardiovaskulären Risiko ein, was eine neue Art der Patientenklassifizierung ist im Vergleich zu der bisherigen therapeutischen Zuordnung in Primär- oder Sekundärpräventionsgruppen kardiovaskulärer Erkrankungen“, sagte Eckel.

\r\n\r\n

\r\n","createDate":"2019-09-10T18:23:00","status":1,"picture":"https://cdn.clinicways.com/news/794008f0-f041-4135-a55c-f363f1177c4d/Main.JPEG","guid":"794008f0-f041-4135-a55c-f363f1177c4d","newsType":1,"seoUrl":"herzschutz-bei-typ-2-diabetes-esc-leitlinie-setzt-auf-sglt2-hemmer-und-glp-1-ag","author":null,"categoryid":9,"mainCategoryid":0,"categoryName":"Obezite ve Metabolik Cerrahi","shortDescription":null,"tag":null,"categorySeo":null,"parentid":0,"referanceWebsite":null,"categoryicon":"category-icon-obesity","categorycolor":"3c989b","language":"En","newsList":[],"doctors":[]}]

The current situation in Turkey

\r\nEntry form and corona test

\r\n1. New infections

2. Dead, recovered, active cases

3. 7 day incidence

4. R value

5. Intensive care bed occupancy in Germany

Japan relied on citizens' sense of responsibility

New infections reported daily skyrocketed

Experts warn of overloading the health system

Previously: Infectious up to ten days after the onset of symptoms

From day 9 no living virus was detected

Study director suggests shorter isolation periods

Social and health problems are inevitable

When the food suddenly tastes boring

Early diagnosis is important

\r\nIncorporating walnuts into your diet reduces inflammation

\r\n How does LCN2 work?

LCN2 in mice and monkeys

The evidence so far

Why is Obesity a Risk Factor?

Missing BMI data

1) Consume too many calories

2) Lead a sedentary lifestyle

3) Not getting enough sleep

4) Endocrine Disruptors

5) Medication and weight gain

6) Is Obesity Self-Persistent?

7) Obesity gene

European governments set priorities for gender equality

Lower life satisfaction among girls

High rates of violence against women

Gender inequalities for women in the workforce

Many years lived in ill health

What causes bad breath? And what can you do about it?

Tips to improve bad breath

Gender Medicine: The science of the "little difference"

How do women deal with their health?

Heart attack is not just for men

The risk increases after the menopause

Men or women - who is more stressed?

1.Enjoy food diversity

2.Vegetables and fruit – take ‘5 a day’

3.Favour whole-grain foods

4.Complete the choice with animal-based foods

6.Reduce sugar and salt intake

7. Water is the best choice

8.Prepare carefully cooked dishes

9. Mindful eating and enjoying

10.Watch your weight and stay active

Obesity and its root causes

1.Obesity is a disease with different causes,

2. A Surgery is no wonder.

3. The aftercare process is as important as the surgical success of the surgeon you are operated on.

4. Answer the opinions of your family and friends appropriately.

5. Remember that you have to change your old habits together with your old life.

6. You are not alone. \r\n

7. If you are unsure, postpone the operation.

8 . Get ready for a new life and not for a lifelong diet.

9. Don't be afraid. \r\n

10. Make sure you get your information from the right source.

Arts and health throughout life

Arts in health care

Policy considerations

Definition of “arts”

Consequences of severe obesity

Link between breastfeeding and obesity

Why do skin sagging?

What are the factors of skin sagging?

\r\n1. Ask the question correctly

\r\n2. Examine the science of answers

\r\n3. Consult your doctor first

Structure of human hair

\r\nHair Growth Cycle

How to identify hair loss

\r\nSub-items on hair loss

Do a puzzle or two.

Get your olive oil fix.

Have more fish.

Eat more salad.

6. You are not alone.
\r\n

9. Don't be afraid.
\r\n

2. Asking often what the main point is

3. Asking if you can interrupt them

5. Telling them you have no time

6. Agreeing on a specific talk time

Tip 1: Repeatedly stop yourself from thinking about it.

Tip 2: Change the context.

Tip 3: Make a stronger memory.

Tip 4: Distract your mind with a positive aspect.

Tip 5: Change the perspective.

Exercise can make you as happy as a 

More exercise is not always better